Research Interest: clinical and genetics of metabolic bone diseases; clinical and genetics of familial and sporadic neuroendocrine tumors.

Grants: • 1992 Grant Meeting: "International Conferences On Calcium Regulating Hormones, Florence, 24 to 29 April 1992. Awarded by the Scientific Program Committee and Executive Committee.

• 2009: Lifetime Career Achievement Award of the Italian Society of Osteoporosis and Mineral Metabolism and Disease of the Skeleton, Torino, November 20, 2009.

URL: ORCID ID https://orcid.org/0000-0002-6739-4417;

List of Publications:
PUBBLICAZIONI SU RIVISTE INTERNAZIONALI

1.    de Leonardis V., De Scalzi M., Falchetti A., Cinelli P., Croppi E., Livi R., Scarpelli L., Scarpelli P.T.: Echocardiographic evaluation of children with and without family hystory of essential hypertension. Am. J. Hypert. 1:305-308, 1988. [IF 3.496; 2005]

2.    de Leonardis V., De Scalzi M., Perrin A., Falchetti A., Cinelli P.: Systolic time intervals and their relationship to arterial blood pressure. J. Hypert. 4 (suppl. 5): S319-S321, 1986. [IF 5.218; 2005]

3.    Friedman E, Sakaguchi K., Bale A.E., Falchetti A., Streeten E., Zimering M., Weinstein L., Mc Bride W.O., Nakamura Y., Brandi M. L., Norton J. A., Aurbach G. D., Spiegel A. M., Marx S. J.: Parathyroid tumors in familial multiple endocrine neoplasia type 1 and in sporadic adenomas show clonal losses of alleles within chromosome 11. New Engl. J. Med. 321, 213, 1989. [44.016; 2005]

4.    Falchetti A., Bale A. E., Amorosi A., Bordi C., Cicchi P., Bandini S., Marx S. J., Brandi M. L.: Progression of uremic hyperparathyroidism involves allelic loss on chromosome 11. J. Clin. End. Metab. 76: 139, 1993. [6.02, 2005]

5.    Brandi M.L., Weber G., Svensson A., Falchetti A., Tonelli F., Castello R., Furlani L., Scappaticci S., Fraccaro M., Larsson C. Homozygotes for the autosomal dominant neoplasia syndrome (MEN I). Am J Hum Genet. 53:1167-1172, 1993. [12.649; 2005]

6.    Bani Sacchi T., Bani D., Brandi M.L., Falchetti A., Bigazzi M. Relaxin influences growth, differentiation and cell-cell adhesion of human breast-cancer cells in culture. Int J Cancer. 57:129-134, 1994. [4.7; 2005]

7.    Bordi C., Falchetti A., Buffa R., Azzoni C., D’Adda T., Caruana P., Rindi G., Brandi M. L. Production of Basic Fibroblast Growth Factor by Gastric Carcinoid Tumors and Their Putative Cells of Origin. Hum Pathol. 25(2):175-180, 1994. [2.55; 2005]

8.    Falchetti A., Morelli A., Brandi M.L. Allelic loss on chromosome 11q12-13 in visceral lipoma and intestinal carcinoid from two patients with Multiple Endocrine Neoplasia Type 1. J Endocrinol Invest. 17(Suppl. 2 al #3):77, 1994. [1.496; 2005]

9.    Amorosi A., Nesi G., Spini S., Tonelli F., Falchetti A., Brandi M.L. Histologic Features of Parathyroid Hyperplasia in Multiple Endocrine Neoplasia Type I (MEN I). Diagnostic and Surgical Implications. Acta Chir. Austriaca, 26 (Suppl. 112); 13-15, 1994.

10.    Tonelli F. Spini S., Gabbrielli G., Falchetti A., Brandi M. L. The surgical treatment of hyperparathyroidism in multiple endocrine neoplasia type 1 (MEN 1) syndrome. Acta Chir. Austriaca, 26 (Suppl. 112); 26-28, 1994.

11.    Bordi C., Falchetti A., Azzoni T. et al. Lack of allelic loss at the men 1 gene locus in a non-endocrine adenocarcinoma of a patient with men 1 syndrome. Virchows Archiv. 426: 203-208, 1995. [2.224; 2005]

12.    Morelli A., Falchetti A., Weinstein L. et al. RFLPs analysis of human chromosome 11 region q13 in multiple symmetric lipomatosis and multiple endocrine neoplasia type 1-associated lipomas. Biochem Biophys Res Comm. 207(1):363-368, 1995. [3.0; 2005]

13.    Morelli A., Falchetti A., Castello R., et al. Genetic screening to identify the gene carrier in italian and german kindreds affected by multiple endocrine neoplasia type 1 (MEN 1) syndrome. J Endocrinol Invest. 18:329-335, 1995. [1.496; 2005]

14.    Fiorelli G., Gori F., Frediani U., Morelli A., Falchetti A., Benvenuti S., Masi L., Brandi M. L. Evidence for bioeffects of LY 139478 on the human preosteoclastic cell line FLG 29.1. Biochem Biophys Res Comm. 211(3):857-863, 1995. [3.0; 2005]

15.    Falchetti A., Tonelli F., Brandi M.L. Genetic aspects of molecular basis of parathyroid tissue growth. Italian J Min Electrolyte Metab. 9:73-78, 1995.

16.    Brandi M. L., Falchetti A., Tonelli F., Bordi C. Editorial: Are allelic losses at 11q13 universal in MEN 1 tumors? J. Clin. Endocrinol. Metab. 81(9):3162-3163, 1996. [6.02, 2005]

17.    Forti G., Falchetti A., Santoro S., Davis D. L., Wilson J. D., Russell D. W. Steroid 5à-reductase 2 deficiency: virilization in early infancy may be due to partial function of mutant enzyme. Clin. Endocrinol. 44:477-482, 1996. [3.412, 2005]

18.    Fiorelli G., Formigli L., Zecchi Orlandini S., Gori F., Falchetti A., Morelli A., Tanini A., Benvenuti S., Brandi M. L. Characterization and function of the receptor for IGF-1 in human preosteoclastic cells. Bone 18(3):269-276, 1996. [3.939, 2005]

19.    Morelli A., Falchetti A., Amorosi A., Tonelli F., Bearzi I., Ranaldi R., Tomassetti P., Brandi M. L. Clonal analysis by chromosome 11 microsatellite-PCR of microdissected parathyroid tumors from MEN 1 patients. Biochem. Biophys. Res. Comm., 227:736-742, 1996. [3.0, 2005]

20.    Bordi C., Falchetti A., Azzoni C., D’Adda T., Canavese G., Guariglia A., Santini D., Tomassetti P., Brandi M. L. Aggressive forms of gastric neuroendocrine tumors in multiple endocrine neoplasia type 1. Am. J. Surg. Pathol. 21(9) :1075-1082, 1997. [4.377 2005]

21.    Benvenuti S., Masi L., Falchetti A., Mancini L., Formigli L., Zecchi S., Amorosi A., Tonelli F., Brandi M. L. HPE cells: A clonal endothelial cell line established from human parathyroid tissue (Human Parathyroid Cell Line). Endothelium 5:37-49, 1997. [2.343, 2005]

22.    Falchetti A., Morelli A., Amorosi A., Tonelli F., Fabiani S., Martineti V., Brandi M. L. Allelic loss in parathyroid tumors from MEN 1 homozygotes. J. Clin. Endocrinol. Metab. 82(7) :2278-2282, 1997. [6.02, 2005]

23.    Giorgi L., Fanfani E., Trovati F., Falchetti A., Novelli GP. Immediate-early genes expression in spinal cord as related to acute noxious stimulus. Int J Clin Pharmacol Res. 17(2-3): 59-61, 1997. [1.057, 2005]

24.    Falchetti A., Brandi M. L. Genetic testing for multiple endocrine neoplasias. Endocrine Related Cancer, 5:37, 1998. [4.905, 2005]

25.    Masi L., Becherini L., Gennari L., Colli E., Mansani R., Falchetti A., Cepollaro C., Gonnelli S., Tanini A., Brandi M.L.: Allelic variants of human calcitonin receptor: distribution and association with bone mass in postmenopausal Italian women. Bioch Bioph Res Comm 245:622, 1998. [3.0, 2005]

26.    L. Masi, L. Becherini, E. Colli, L. Gennari, R. Mansani, A. Falchetti, A.M. Becorpi, C. Cepollaro, S. Gonnelli, A. Tanini, M.L. Brandi: Polymorphisms of the calcitonin receptor gene are associated with bone mineral density in postmenopausal Italian women. Biochem Biophys Res Comm, 248: 190, 1998. [3.0, 2005]

27.    L. Gennari, L. Becherini, R. Mansani, L. Masi, A. Falchetti, A.M. Morelli, E. Colli, S. Gonnelli, C. Cepollaro, M.L. Brandi: Fok I polymorphhism of the vitamin D receptor gene, bone mineral density and osteoporotic fractures in postmenopausal Italian women. J Bone Min Res. 14(8):1379-86, 1999. [6.527, 2005]

28.    Falchetti A, Becherini Lucia, Martineti Valentina, Morelli Annamaria, Benvenuti Susanna, Picariello Lucia, Gennari Luigi, Lampugnani Rinaldo, Bordi Cesare, Brandi Maria Luisa. Telomerase Repeat Amplification Protocol (Trap): A New Molecular Marker For Parathyroid Carcinoma. Biochem Biophys Res Comm. 26(5):252-5, 1999. [3.0, 2005]

29.    Morelli A., Falchetti A., Martineti V., Becherini L., Mark M., Friedman E., Brandi M. L. MEN1 gene mutation analysis in Italian patients affected by Multiple Endocrine Neoplasia type 1 syndrome. Eur J Endocrinol. 142(2):131-137, 2000. [2.962, 2005]

30.    Becherini L., Gennari L., Masi L., Mansani R. Massart F., Morelli A., Falchetti A., Gonnelli S., Fiorelli G., Tanini A., Brandi M. L. Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor alfa gene and their relationship to bone mass variation in postmenopausal women. Human Molecular Genetics 9(12):2043-2050, 2000. [7.764, 2005]

31.    Picariello L., Benvenuti S., Recenti R., Formigli L., Falchetti A., Morelli A., Masi L., Cicchi P., Tonelli F., Brandi M.L. Microencapsulation of human parathyroid cells: an “in vitro” study. Journal of Surgical Research 96(1):81-89, 2001. [1.956, 2005]

32.    Masi L., Becherini L., Gennari L., Amedei A., Colli E., Falchetti A., Farci M., Silvestri S., Gonnelli S., Brandi M. L. Polymorphism of the Aromatase gene in postmenopausal women: distribution and correlation with bone mass and fracture risk. J. Clin. Endocrinol. Metab, 86(5): 2263-2269, 2001. [6.02, 2005]

33.    Mark M., Morelli A., Brandi M. L., Falchetti A., Olchovski D., Arnaldi G., Mantero F., Friedman E. Somatic mutation analysis of the MEN1 gene in adrenocrotical tumors using denaturing gradient gel electrophoresis (DGGE). Journal of Endocrine Genetics, 2:21-27, 2001.

34.    Brandi ML., Gennari L., Matucci Cerinic M., Becherini L., Falchetti A., Masi L., Gennari C., Reginster JY. Genetic markers of osteoarticular disorders: facts and hopes. Arthritis Research, 3:270-280, 2001. [2.965, 2005]

35.    Morelli A., Falchetti A., Brandi ML. Gene mutations in Multiple Endocrine Neoplasia type 1. Topical Endocrinology, 18:6-9, July 2001.

36.    L. Gennari, L. Becherini, A. Falchetti, L., Masi, F. Massart, Brandi M.L. Genetics of osteoporosis: role of steroid hormone receptor gene polymorphisms. Journal of Steroid Biochemistry & Molecular Biology 81(1):1-24, 2002. [2.866, 2005]

37.    Brandi ML, Gagel RF, Angeli A, Bilezikian JP, Beck-Peccoz P, Bordi C, Conte-Devolx B, Falchetti A, Gheri RG, Libroia A, Lips CJ, Lombardi G, Mannelli M, Pacini F, Ponder BA, Raue F, Skogseid B, Tamburrano G, Thakker RV, Thompson NW, Tomassetti P, Tonelli F, Wells SA Jr, Marx SJ. Guidelines for diagnosis and therapy of MEN type 1 and type 2. J Clin Endocrinol Metab 2001 Dec;86(12):5658-71. [6.02, 2005]

38.    Falchetti A. Genetics of osteoarticular disorders, Florence, Italy, 22-23 February 2002. Arthritis Res 4(5):326-31, 2002. [2.965, 2005]

39.    Vezzoli G, Tanini A, Ferrucci L, Soldati L, Bianchin C, Franceschelli F, Malentacchi C, Porfirio B, Adamo D, Terranegra A, Falchetti A, Cusi D, Bianchi G, Brandi ML. Influence of calcium-sensing receptor gene on urinary calcium excretion in stone-forming patients. J Am Soc Nephrol 13(10):2517-23, 2002. [7.240, 2005]

40.    Massart F, Becherini L, Marini F, Noci I, Piciocchi L, Del Monte F, Masi L, Falchetti A, Tanini A, Scarselli G, Brandi L. Analysis of estrogen receptor (ERa and ERb) and progesterone receptor (PR) polymorphisms in uterine leiomyomas. Med Sci Monit 9(1):BR25-30, 2003.

41.    Cioppi F, Falchetti A, Masi L, Brandi ML. Dynamic investigation for evaluation of calcium metabolism and parathyroid function. J Endocrinol Invest. 2003;26(7 Suppl):83-91. [1.496, 2005]

42.    Falchetti A., M. Di Stefano, F. Marini, F. Del Monte, C. Mavilia, D. Strigoli, M. L. De Feo, G. Isaia, L. Masi, A. Amedei, F. Cioppi, V. Ghinoi, S. Maddali Bongi, G. Di Fede, C. Sferrazza, G. B. Rini, D. Melchiorre, M. Matucci-Cerinic and M. L. Brandi. Two novel mutations at exon 8 of Sequestosome 1 gene (SQSTM1) in an Italian series of patients affected by Paget’s disease of bone (PDB). Journal of Bone and Mineral Research 19(6):1013-7, 2004. [6.527, 2005]

43.    Falchetti A. "Calcium agonists in hyperparathyroidism" Invited review Expert Opin Investig Drugs. 2004 Mar;13(3):229-44. [3.267, 2005]

44.    Brandi ML, Falchetti A. Genetics of primary hyperparathyroidism. Urol Int. 2004;72 Suppl 1:11-6. [0.585, 2005]

45.    Gennari L, Masi L, Merlotti D, Picariello L, Falchetti A, Tanini A, Mavilia C, Del Monte F, Gonnelli S, Lucani B, Gennari C, Brandi ML. A Polymorphic CYP19 TTTA Repeat Influences Aromatase Activity and Estrogen Levels in Elderly Men: Effects on Bone Metabolism. J Clin Endocrinol Metab. 2004 Jun;89(6):2803-10. [6.02, 2005]

46.    Falchetti A., Vezzosi G., Gambaro G. Genetics of primary hypercalciuria. Clinical Cases in Mineral and Bone Metabolism. 2004, 1:27-34.

47.    Croppi E., Vitale C., Bevilacqua M., Borghi L., Caudarella R., Falchetti A., Gambero G., Marangella M., Trinchieri A., Vezzosi G., Brandi ML. Consensus statement on diagnosis of primary hypercalciuria. Clinical Cases in Mineral and Bone Metabolism. 2004, 1:73-75.

48.    Lucia Bacciottini, Annalisa Tanini, Alberto Falchetti, Laura Masi, Francesco Franceschelli, Barbara Pampaloni, Gianluca Giorgi, Maria Luisa Brandi. Calcium bioavailability from a calcium-rich mineral water, with some observations on method. J Clin Gastroenterol. 2004; 38(9):761-6. [2.258, 2005]

49.    Tonelli F, Fratini G, Falchetti A, Nesi G, Brandi ML. Surgery for gastroenteropancreatic tumours in multiple endocrine neoplasia type 1: review and personal experience. J Intern Med. 2005 Jan;257(1):38-49. [4.04, 2005]

50.    Falchetti A, Marini F, Masi L, Brandi ML Genetic aspects of Paget’s disease of bone. Clinical Cases in Mineral and Bone Metabolism. 2004, I(3):191-202.

51.    Ferolla P, Falchetti A, Filosso P, Tomassetti P, Tamburrano G, Avenia N, Daddi G, Puma F, Ribacchi R, Santeusanio F, Angeletti G, Brandi ML. Thymic Neuroendocrine Carcinoma (Carcinoid) in MEN1 Syndrome: the Italian series. J Clin Endocrinol Metab. 2005 May;90(5):2603-9. [6.02, 2005]

52.    Ulivieri FM, Falchetti A, Marini F, Brandi ML, Piodi LP, Crespi A, Verdoia C, Gerundini P. A familial case of Paget’s disease of bone with mutation at exon 8 of the sequestosome 1 (SQSTM1/p62) gene. Clinical Cases in Mineral and Bone Metabolism 2004, I(3): 231-33.

53.    Falchetti A, Franchi A, Bordi C, Mavilia C, Masi L, Cioppi F, Recenti R, Picariello L, Marini F, Del Monte F, Ghinoi V, Martineti V, Tanini A, Brandi ML. Azidothymidine induces apoptosis and inhibits cell growth and telomerase activity of human parathyroid cancer cells in culture. J Bone Miner Res. 2005 Mar;20(3):410-8. [6.527, 2005]

54.    V Martineti, L Picariello§, I Tognarini, S Carbonell Sala, A Gozzini, C Azzari, C Mavilia, A Tanini, A Falchetti, G Fiorelli, F Tonelli And M L Brandi. ERb is a potent inhibitor of cell proliferation in HCT8 human colon cancer cell line through regulation of cell cycle components. Endocr Rel Cancer 12(2):455-69, 2005. [4.905, 2005]

55.    Falchetti A., Marini F., Tonelli F, Brandi M. L. Lessons from genes mutated in multiple endocrine neoplasia (MEN) syndromes. Ann. Endocrinol 2005; 66, 3:195-205. [0.506, 2005]

56.    Falchetti A., Di Stefano M., Marini F., Del Monte F., Gozzini A., Masi L., Tanini A., Amedei A., Carossino A., Isaia G. and. Brandi M. L. Segregation of M404V mutation of p62/sequestosome 1 (p62/SQSTM1) gene with polyostotic Paget’s disease of bone in an Italian family. Arthritis Res. & Therapies 2005; 7(6):R1289-95. [2.965, 2005]

57.    A. Falchetti, F. Marini, F. Del Monte et al. Results of a national survey on multiple endocrine neoplasia syndrome type 1 in Italy: a macroaggregate analysis. Clinical Cases in Mineral and Bone Metabolism 2005, II(1): 29-35.

58.    L Gennari, A. Falchetti, Bandini S. et al. Genetic polymorphisms of vitamin D receptor amd calcium sensing receptor gene in uremic secondary hyperparathyroidism: a multicentric Italian study. Clinical Cases in Mineral and Bone Metabolism 2005, II(1): 37-41.

59.    A. Falchetti, Gozzini A., Masi L et al. Allelic loss at the vitamin D receptor (VDR) locus in parathryoid tissue from one patient affected by refractory uremic. Clinical Cases in Mineral and Bone Metabolism 2005, II(1): 53-55.

60.    Francesco Tonelli, Geri Fratini., Gabriella Nesi, Maria Silvia Tommasi., Giacomo Batignani, Alberto Falchetti, and Maria Luisa Brandi. Pancreatectomy in Multiple Endocrine Neoplasia type 1-related gastrinomas and pancreatic endocrine neoplasias. Annals of Surgery 257(1):38-49, 2005. [6.328, 2005]

61.    Carbonell Sala S, Masi L, Marini F, Del Monte F, Falchetti A, Franceschelli F, Brandi ML. Genetics and pharmacogenetics of osteoporosis. J Endocrinol Invest. 2005;28(10 Suppl):2-7. [1.496, 2005]

62.    Ralston SH, Uitterlinden AG, Brandi ML, Balcells S, Langdahl BL, Lips P, Lorenc R, Obermayer-Pietsch B, Scollen S, Bustamante M, Husted LB, Carey AH, Diez-Perez A, Dunning AM, Falchetti A, Karczmarewicz E, Kruk M, Leeuwen JP, Meurs JB, Mangion J, McGuigan FE, Mellibovsky L, Monte FD, Pols HA, Reeve J, Reid DM, Renner W, Rivadeneira F, Schoor NM, Sherlock RE, Ioannidis JP. Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study. PLoS Med. 2006 Feb 21;3(4): e90. [13.800, 2006]

63.    Nuzzo V, Tauchmanova L, Falchetti A, Faggiano A, Marini F, Piantadosi S, Brandi ML, Leopaldi L, Colao A. MEN1 family with a novel frameshift mutation. J Endocrinol Invest. 2006 May; 29(5):450-6. [1.496, 2005]

64.    Tonelli F, Fratini G, Nesi G, Tommasi MS, Batignani G, Falchetti A, Brandi ML. Pancreatectomy in Multiple Endocrine Neoplasia Type 1-Related Gastrinomas and Pancreatic Endocrine Neoplasias. Ann Surg. 2006 Jul; 244(1):61-70. [6.328, 2005]

65.    G. Rindi, G. Klöppel, H. Alhman, M. Caplin, A. Couvelard, W. W. der Herder, B. Erikssson, A. Falchetti, M. Falconi, P. Komminoth, M. Körner, J.M. Lopes, A-M. McNicol, O. Nilsson, A. Perren, A. Scarpa, J-Y. Scoazec, B. Wiedenmann and all other Frascati Consensus Conference participants. TNM STAGING OF FOREGUT (NEURO)ENDOCRINE TUMORS: a consensus proposal including a grading system. Virchows Arch. 449(4):395-401, 2006. [2.224, 2005]

66.    Marini F, Falchetti A, Del Monte F, Carbonell Sala S, Gozzini A, Luzi E, Brandi ML. Multiple Endocrine Neoplasia Type 1. Orphanet J Rare Dis. 2006 Oct 2;1(1):38 [Epub ahead of print]. [1.030, 2006]

67.    Marini F, Falchetti A, Del Monte F, Carbonell Sala S, Tognarini I, Luzi E, Brandi ML. Multiple Endocrine Neoplasia Type 2. Orphanet J Rare Dis. 2006 Nov 14:1-45 [Epub ahead of print]. [1.030, 2006]

68.    Falchetti A. and Maria Luisa Brandi. Hereditary Hyperparathyroidism. Clinical Cases in Mineral and Bone Metabolism, 2006; 3(2):141-149.

69.    Brandi ML and Falchetti A. What is the relationship between Paget's disease of bone and hyperparathyroidism? Journal of Bone and Mineral Research 2006 Dec;21 Suppl 2:P69-74. [6.527, 2005]

70.    A. Falchetti, C. Sferrazza, C. Cepollaro, A. Gozzini, F. Del Monte, L. Masi, N. Napoli, G. Di Fede, V. Cannone, G. Cusumano, M. C. Pandolfo, G. B. Rini, A. Tanini and M. L. Brandi. FokI polymorphism of vitamin d receptor gene correlates with dual x-ray absorptiometry, quantitative ultrasound and bone turnover markers in an italian female population from Lampedusa island. Calcif Tissue Int. 2007 Jan;80(1):15-20. [2.487, 2005]

71.    Cepollaro C, Lauretani F, Gozzini A, Masi L, Falchetti A, Del Monte F, Carbonell-Sala S, Tanini A, Corsi AM, Bandinelli S, Ferrucci L, Brandi ML. Relationship of Volumetric Bone Mineral Density and Structural Parameters with ERalpha Gene Polymorphisms. Calcif Tissue Int. 2007 May;80(5):307-15. Epub 2007 May 16. [2.487, 2005]

72.    Adami S, Bartolozzi P, Brandi ML, Falchetti A, Filipponi P, Gonnelli S, Bianchi G, Isaia GC, Nuti R. Italian guidelines for the diagnosis and treatment of Paget's disease of bone. Reumatismo. 2007 Apr-Jun;59(2):153-68.

73.    Masi L, Falchetti A, Brandi ML. Osteonecrosis in genetic disorders. Clinical Cases in Mineral and Bone Metabolism, 2007; 4(1):27-29.

74.    Falchetti A, Masi L, Brandi ML. Thiazolidinediones and bone. Clinical Cases in Mineral and Bone Metabolism, 2007; 4(2):103-105.

75.    Bacciottini L, Falchetti A, Pampaloni B, Bartolini E, Carossino A, Brandi ML. Phytoestrogens: food or drug? Clinical Cases in Mineral and Bone Metabolism, 2007; 4(2):123-130.

76.    Masi L, Del Monte F, Gozzini A., De Feo ML, Gheri RG, Neri A, Falchetti A, Amedei A, Imbraco R, Mavilia C, Tanini A, Brandi ML. A novel polymorphism at the GNAS1 gene associated with low circulating calcium levels. Clinical Cases in Mineral and Bone Metabolism, 2007; 4(2):139-145.

77.    Masi L, Maddali Bongi S, Angotti C, Del Monte F, Carbonell Sala S, Basetti A, Amedei A, Falchetti A, Brandi ML. The role of osteoprotegerin (OPG) and estrogen receptor (ER-a) gene polymorphisms in rheumatoid arthritis. Clinical Cases in Mineral and Bone Metabolism, 2007; 4(2):156-160.

78.    F Tonelli, T Marcucci; G Fratini; MS Tommasi; A Falchetti, ML Brandi. Is total parathyroidectomy the treatment of choice for hyperparathyroidism in multiple endocrine neoplasia type 1? Ann Surg. 2007 Dec;246(6):1075-82. [6.328, 2005]

79.    Laura Masi, Francesca Del Monte, Alessia Gozzini, Maria Laura De Feo, Riccardo Gionata Gheri, Annasilvia Neri, Alberto Falchetti, Antonietta Amedei, Rosario Imbriaco, Carmelo Mavilia, Annalisa Tanini, Maria Luisa Brandi. A novel polymorphism at the GNAS1 gene associated with low circulating calcium levels. Clinical Cases in Mineral and Bone Metabolism 2007; 4(2): 139-145.

80.    Lucia Bacciottini, Alberto Falchetti, Barbara Pampaloni, Elisa Bartolini, Anna Maria Carossino, Maria Luisa Brandi. Phytoestrogens: food or drug? Clinical Cases in Mineral and Bone Metabolism 2007; 4(2): 123-130.

81.    Laura Masi, Susanna Maddali Bongi, Chiara Angotti, Francesca Del Monte, Silvia Carbonell Sala, Massimo Basetti, Antonietta Amedei, Alberto Falchetti, Maria Luisa Brandi. The role of osteoprotegerin (OPG) and estrogen receptor (ER-α) gene polymorphisms in rheumatoid arthritis. Clinical Cases in Mineral and Bone Metabolism 2007; 4(2): 156-160.

82.    Langdahl BL, Uitterlinden AG, Ralston SH, Trikalinos TA, Balcells S, Brandi ML, Scollen S, Lips P, Lorenc R, Obermayer-Pietsch B, Reid DM, Armas JB, Arp PP, Bassiti A, Bustamante M, Husted LB, Carey AH, Pérez Cano R, Dobnig H, Dunning AM, Fahrleitner-Pammer A, Falchetti A, Karczmarewicz E, Kruk M, van Leeuwen JP, Masi L, van Meurs JB, Mangion J, McGuigan FE, Mellibovsky L, Mosekilde L, Nogués X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Ioannidis JP; APOSS investigators; DOPS investigators; EPOS investigators; EPOLOS investigators; FAMOS investigators; LASA investigators; ERGO investigators; GENOMOS Study. Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study. Bone. 2008 May;42(5):969-81. [3.939, 2005]

83.    Villa C, Magri F, Morbini P, Falchetti A, Scagnelli P, Lovati E, Locatelli D, Canevari FR, Necchi V, Gabellieri E, Guabello G, Chiovato L, Solcia E. Silent Familial Isolated Pituitary Adenomas: Histopathological and Clinical Case Report. Endocr Pathol. 2008 Mar 4. [Epub ahead of print]. [1.099, 2005]

84.    Falchetti A, Marini F, Luzi E, Tonelli F, Brandi ML. Multiple endocrine neoplasms. Best Pract Res Clin Rheumatol. 2008 Mar;22(1):149-63. [1.904, 2005]

85.    van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, Benevolenskaya LI, Ferrari SL, Hallmans G, Hofman A, Husted LB, Kruk M, Kaptoge S, Karasik D, Karlsson MK, Lorentzon M, Masi L, McGuigan FE, Mellström D, Mosekilde L, Nogues X, Pols HA, Reeve J, Renner W, Rivadeneira F, van Schoor NM, Weber K, Ioannidis JP, Uitterlinden AG; GENOMOS Study. Collaborators Falchetti A et al. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA. 2008 Mar 19;299(11):1277-90. [23.332, 2005]

86.    Falchetti A, Cilotti A, Vaggelli L, Masi L, Amedei A, Cioppi F, Tonelli F, Brandi ML. A patient with MEN1-associated hyperparathyroidism, responsive to cinacalcet. Nat Clin Pract Endocrinol Metab. 2008 Jun;4(6):351-7. [3.678, 2007]

87.    Marini F, Falchetti A, Silvestri S, Bagger Y, Luzi E, Tanini A, Christiansen C, Brandi ML. Modulatory effect of farnesyl pyrophosphate synthase (FDPS) rs2297480 polymorphism on the response to long-term amino-bisphosphonate treatment in postmenopausal osteoporosis. Curr Med Res Opin. 2008 Sep;24(9):2609-15. [2.945, 2005]

88.    F. Marini, S. Carbonell Sala, A. Falchetti, D. Caramelli, M.L. Brandi. The genetic ascertainment of multiple endocrine neoplasia type 1 (MEN1) syndrome by ancient DNA analysis. J Endocrinol Invest. 2008 Oct;31(10):905-9. [1.496, 2005]

89.    D Najat, T Garner, T Hagen, B Shaw, PW Sheppard, A Falchetti, F Marini, ML Brandi, JE Long, JR Cavey, MS Searle, R Layfield. Characterisation of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone. J Bone Miner Res. 2008 Dec 2, 24(4):632-42. [6.527, 2005]

90.    Falchetti A, Di Stefano M, Marini F, Ortolani S, Ulivieri FM, Bergui S, Masi L, Cepollaro C, Benucci M, Di Munno O, Rossini M, Adami S, Del Puente A, Isaia G, Torricelli F, Brandi ML, on behalf of the GenePage Project. Genetic epidemiology of Paget’s disease of bone in Italy: sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial Italian cases of Paget’s disease of bone. Calcif Tissue Int. 2009 Jan;84(1):20-37. [2.487, 2005]

91.    Falchetti A., Marini F., Giusti F., Cavalli L., Cavalli T., Brandi M. L. DNA-based Test: When and Why to apply it to Primary Hyperparathyroidism Clinical Phenotypes. J Intern Med. 2009 Jul;266(1):69-83. [4.04, 2009]

92.    Alberto Falchetti and Maria Luisa Brandi. MEN1-related states, MEN1 variants, MEN1 phenocopies: are they only a nosologic issue? J Clin Endocrinol Metab. 2009 May; 94(5):1518-20. [6.02, 2008]

93.    Masi L, Gozzini A, Franchi A, Campanacci D, Amedei A, Falchetti A, Franceschelli F, Marcucci G, Tanini A, Capanna R, Brandi ML. A novel recessive mutation of fibroblast growth factor-23 in tumoral calcinosis. J Bone Joint Surg Am. 2009 May;91(5):1190-8. [2.444, 2006]

94.    Tonelli F, Marcucci T, Giudici F, Falchetti A, Brandi ML. Surgical Approach in Hereditary Hyperparathyroidism. Endocr J. 2009;56(7):827-41. [1.600, 2008]

95.    Laura Papi, Domenico Palli, Laura Masi, Anna Laura Putignano, Caterina Congregati, Ines Zanna, Francesca Marini, Francesca Giusti, Ettore Luzi, Francesco Tonelli, Maurizio Genuardi, Maria Luisa Brandi, Alberto Falchetti. Germline mutations in MEN1 and BRCA1 genes in a female subject with familial Multiple Endocrine Neoplasia type 1 and inherited breast/ovarian cancer syndromes: a case report. Cancer Genet Cytogenet. 2009 Nov;195(1):75-9. [1.529, 2003]

96.    Falchetti Alberto, Marini Francesca, Luzi Ettore, Giusti Francesca, Cavalli Loredana, Cavalli Tiziana, Brandi Maria Luisa. Multiple Endocrine Neoplasia Type 1 (MEN1): not only inherited endocrine tumors. Genet Med. 2009 Dec;11(12):825-35. [3.716, 2008]

97.    Antonio Cilotti, Alberto Falchetti. Male osteoporosis and androgenic therapy: from testosterone to SARMs. Clinical Cases in Mineral and Bone Metabolism 2009; 6(3): 229-233.

98.    Loredana Cavalli, Tiziana Cavalli, Gemma Marcucci, Alberto Falchetti, Laura Masi, Maria Luisa Brandi. Biological effects of various regimes of 25-hydroxyvitamin D3 (calcidiol) administration on bone mineral metabolism in postmenopausal women. Clinical Cases in Mineral and Bone Metabolism 2009; 6(2): 169-173.

99.    Edwin Jobany Parra Prada, Khodr Haidar Hassan, Maria Luisa Brandi, Alberto Falchetti. Polyostotic form of fibrous dysplasia in a 13 years old Colombian girl showing clinical and biochemical response to neridronate intravenous therapy. Clinical Cases in Mineral and Bone Metabolism 2009; 6(3): 264-265.

100.    Vincenzo Nuzzo, T. Ferrara, Alfonso Zuccoli, Raffaella Brunetti-Pierri, Roberto De Rosa, Alberto Falchetti, R. Franco, and Nicola Brunetti-Pierri. Infiltrating giant cell tumor in a case of Paget’s disease of bone. Arch Osteoporos. 2009 December; 4(1-2): 91–94.

101.    Francesca Giusti, Alberto Falchetti, Francesco Franceschelli, Francesca Marini, Annalisa Tanini and Maria Luisa Brandi Thyroid Cancer: Current Molecular Perspectives. J Oncol. 2010; 2010:351679.

102.    Romei C, Mariotti S, Fugazzola L, Taccaliti A, Pacini F, Opocher G, Mian C, Castellano M, degli Uberti E, Ceccherini I, Cremonini N, Seregni E, Orlandi F, Ferolla P, Puxeddu E, Giorgino F, Colao A, Loli P, Bondi F, Cosci B, Bottici V, Cappai A, Pinna G, Persani L, Verga U, Boscaro M, Castagna MG, Cappelli C, Zatelli MC, Faggiano A, Francia G, Brandi ML, Falchetti A, Pinchera A, Elisei R; ItaMEN network. Multiple endocrine neoplasia type 2 syndromes (MEN 2): results from the ItaMEN network analysis on the prevalence of different genotypes and phenotypes. Eur J Endocrinol. 2010 August; 163(2):301-8. [3.539, 2009]

103.    Falchetti A, Masi L, Brandi ML. Paget's disease of bone: there's more than the affected skeletal--a clinical review and suggestions for the clinical practice. Curr Opin Rheumatol. 2010 Jul;22(4):410-23. [4.600, 2010]

104.    Maria Giovanna Filippella, Antongiulio Faggiano, Alberto Falchetti, Annamaria Colao, Carlo Rosa, Carlo Poti, Corrado Musso, Giulio Doveri, and Maria Luisa Brandi. Risk of fractures and bone abnormalities in postmenopausal women with type 2 diabetes mellitus. Clin Cases Miner Bone Metab. 2010 May–Aug; 7(2): 126–129.

105.    Roberta Cosso, Vincenzo Nuzzo, Alfonso Zuccoli, Maria Luisa Brandi, and Alberto Falchetti. Giant cell tumor in a case of Paget's disease of bone: an aggressive benign tumor exhibiting a quick response to an innovative therapeutic agent. Clin Cases Miner Bone Metab. 2010 May–Aug; 7(2): 145–152.

106.    Genetic aspects of the Paget's disease of bone: concerns on the introduction of DNA-based tests in the clinical practice. Advantages and disadvantages of its application. Falchetti A, Marini F, Masi L, Amedei A, Brandi ML. Eur J Clin Invest. 2010 Jul;40(7):655-67. [2.643, 2009]

107.    Ribozyme-mediated compensatory induction of menin-oncosuppressor function in primary fibroblasts from MEN1 patients. Luzi E, Marini F, Tognarini I, Carbonell Sala S, Galli G, Falchetti A, Brandi ML. Cancer Gene Ther. 2010 Nov;17(11):814-25. [3.126, 2009]

108.    Genetic screening for multiple endocrine neoplasia syndrome type 1 (MEN-1): when and how. Falchetti A. F1000 Med Rep. 2010 Feb 24;2. pii: 14.

109.    LRP5 gene polymorphism and cortical bone. Lauretani F, Cepollaro C, Bandinelli S, Cherubini A, Gozzini A, Masi L, Falchetti A, Del Monte F, Carbonell-Sala S, Marini F, Tanini A, Corsi AM, Ceda GP, Brandi ML, Ferrucci L. Aging Clin Exp Res. 2010 Aug;22(4):281-8. [1.26, 2009].

110.    Pharmacogenetics of bisphosphonate-associated osteonecrosis of the jaw. Marini F, Tonelli P, Cavalli L, Cavalli T, Masi L, Falchetti A, Brandi ML. Front Biosci (Elite Ed). 2011 Jan 1;3364-70. [3.603, 2009]

111.    MEN syndromes. Falchetti A. Tumori. 2010 Sep-Oct;96(5):823-6. [0.86, 2009]

112.    Bargellini T, Cantelli G, Bruscino A, Falchetti A, Giusti F, Brandi ML, Valeri A. Left laparoscopic adrenalectomy for pheochromocytoma in MEN 2B: case report. G Chir. 2011 Mar;32(3):132-4.

113.    The Genetic Determinants of Paget's Disease (GDPD) Consortium, Albagha OM, Wani SE, Visconti MR, Alonso N, Goodman K, Brandi ML, Cundy T, Chung PY, Dargie R, Devogelaer JP, Falchetti A, Fraser WD, Gennari L, Gianfrancesco F, Hooper MJ, Van Hul W, Isaia G, Nicholson GC, Nuti R, Papapoulos S, Montes JD, Ratajczak T, Rea SL, Rendina D, Gonzalez-Sarmiento R, Di Stefano M, Ward LC, Walsh JP, Ralston SH. Genome-wide association identifies three new susceptibility loci for Paget's disease of bone. Nat Genet. 2011 May 29;43(7):685-9. [34.284, 2010].

114.    Falchetti A, Cavalli L, Cavalli T, Giusti F, Marcucci G, Marini F, Brandi ML. Molecular diagnosis of parathyroid carcinoma: a reality in the near future. Expert Opin Med Diagn. 2012 Jan;6(1):27-37.

115.    Falchetti A, Gozzini A, Terranegra A, Soldati L, Vezzoli G, Leoncini G, Giusti F, Franceschelli F, Masi L, Tanini A, Cavalli L, Brandi ML. A novel germline inactivating mutation in the CaSR gene in an italian kindred affected by Familial Hypocalciuric Hypercalcemia. Eur J Endocrinol. 2012 Feb 7. [Epub ahead of print]. [3.9, 2010].

116.    Ettore Luzi, Francesca Marini, Isabella Tognarini, Gianna Galli, Alberto Falchetti and Maria Luisa Brandi. The regulatory network menin-microRNA 26a as possible target for a RNA-based therapy of bone diseases. Nucleic Acid Ther. 2012 Apr;22(2):103-8. [2.9, 2010].

117.    Malavolta N, Rossi E, Buffa A, Falchetti A. Fragility fractures: clinical and therapeutic aspects. J Biol Regul Homeost Agents. 2015 Oct-Dec;29(4):761-9. [2.04, 2016].

118.    Roberta Cosso & Alberto Falchetti (2016): Vitamin K and bone metabolism: the myth and the truth, Expert Review of Precision Medicine and Drug Development, DOI: 10.1080/23808993.2016.1174061.

119.    Falchetti A. Genetics of multiple endocrine neoplasia type 1 syndrome: what's new and what's old. F1000Res. 2017, Jan 24;6.

120.    Eller-Vainicher C, Palmieri S, Cairoli E, Goggi G, Scillitani A, Arosio M, Falchetti A, Chiodini I. Protective Effect of Denosumab on Bone in Older Women with Primary Hyperparathyroidism. J Am Geriatr Soc. 2018 Jan 24. doi: 10.1111/jgs.15250. [Epub ahead of print] [4.388, 2017].

121.Roberto Cesareo, Roberto Attanasio, Marco Caputo, Roberto Castello, Iacopo Chiodini, Alberto Falchetti, Rinaldo Guglielmi, Enrico Papini, Assunta Santonati, Alfredo Scillitani, Vincenzo Toscano, Vincenzo Triggiani, Fabio Vescini, Michele Zini and on behalf of AME and Italian AACE Chapter. Italian Association of Clinical Endocrinologists (AME) and Italian Chapter of the American Association of Clinical Endocrinologists (AACE) Position Statement: Clinical Management of Vitamin D Deficiency in Adults. Nutrients 2018, 10, 546; doi:10.3390/nu10050546. [I. F. 4,187].

122. Cosso Roberta and Falchetti Alberto. Mitochondriopathies and bone health. Journal of Trends in Biomedical Research 2018 Volume 1(1): 1-7. doi:10.15761/JTBR.1000101.

123. Alberto Falchetti and Roberta Cosso. The interaction between vitamin C and bone health: a narrative review. Expert Review of Precision Medicine and Drug Development https://doi.org/10.1080/23808993.2018.1482211.

124. Palermo A, Capoluongo E, Del Toro R, Manfrini S, Pozzilli P, Maggi D, Defeudis G, Pantano F, Coppola R, Di Matteo FM, Raffaelli M, Concolino P, Falchetti A. A novel germline mutation at exon 10 of MEN1 gene: a clinical survey and positive genotype-phenotype analysis of a MEN1 Italian family, including monozygotic twins. Hormones (Athens). 2018 Sep;17(3):427-435. [I. F. 1,237].

125. Falchetti A. Genetics of parathyroids disorders: overview. Best Practice & Research Clinical Endocrinology & Metabolism (accepted for publication). [I. F. 4,791].

126. Eller-Vainicher C, Falchetti A. Management of familial Hyperparathyroid syndromes: MEN1, MEN2, HPT-Jaw tumour, FHH, neonatal severe hyperparathyroidism, familial isolated hyperparathyroidism. Best Practice & Research Clinical Endocrinology & Metabolism (accepted for publication). [I. F. 4,791].

127. Vescini F, Falchetti A, Tonelli V, Carpentieri M, Cipri C, Cosso R, Kara E, Triggiani V, Grimaldi F. Mazabraud's Syndrome: A Case Report And Up-To-Date Literature Review. Endocr Metab Immune Disord Drug Targets. 2018 Dec 25. doi: 10.2174/1871530319666181226103700 [I. F. 2.013].

128. Gennari L, Rendina D, Falchetti A, Merlotti D. Paget's Disease of Bone. Calcif Tissue Int. 2019 Jan 23. doi: 10.1007/s00223-019-00522-3. [I. F. 3,293].

129. Merlotti D, Falchetti A, Chiodini I, Gennari L. Efficacy and safety of abaloparatide for the treatment of post-menopausal osteoporosis. Expert Opin Pharmacother. 2019 Mar 11:1-7. [I. F. 3.469].

130. Eller-Vainicher C, Falchetti A, Gennari L, Cairoli E, Bertoldo F, Vescini F, Scillitani A, Chiodini I. DIAGNOSIS OF ENDOCRINE DISEASE: Evaluation of bone fragility in endocrine disorders. Eur J Endocrinol. 2019 Apr 1. pii: EJE-18-0991.R1. [I. F. 4,333]

131. Cesareo R, Falchetti A, Attanasio R, Tabacco G, Naciu AM, Palermo A. Hypovitaminosis D: Is It Time to Consider the Use of Calcifediol? Nutrients. 2019 May 6;11(5). pii: E1016. [I. F. 4,196]

132. Chiodini I, Gaudio A, Eller-Vainicher C, Morelli V, Aresta C, Zhukouskaya VV, Merlotti D, Orsi E, Barbieri AM, Fustinoni S, Polledri E, Gennari L, Falchetti A, Carnevale V, Persani L, Scillitani A. Cortisol secretion, sensitivity, and activity are associated with hypertension in postmenopausal eucortisolemic women. J Clin Endocrinol Metab. 2019 May 21. pii: jc.2019-00037. doi: 10.1210/jc.2019-00037. [I. F. 59255]

19 October 1998 medical specialization in surgical pathology in Federico II university- Faculty of medicine- Naples- Italy;

28 July 1993 Degree in medicine in Federico II University- Faculty of medicine- Naples- Italy; FROM NOVEMBER 1999 TO NOWDAYS : MEDICAL DOCTOR  SPECIALIZED IN SURGICAL PATHOLOGY IN CASALE MONFERRATO HOSPITAL (PIEDIMONT, ITALY); AZIENDAL RESPONSIBLE OF PERINATAL PATHOLOGY

 AZIENDAL RESPONSIBLE OF CYTOPATHOLOGY (FNAC PATHOLOGY OF BREAST, THYROID, SALIVARY GLANDS, GASTROENTERIC MASS, URINARY PATHOLOGY , THIN PREP SLIDES)

Research Interest: perinatal pathology; cytopathology; pulmonar pathology; gastroenteric neoplasia

publications:
  Mixed Mullerian Tumor Primitive of Peritoneum: Report of a Case . Stefania Erra, Simone Lo Mastro, Ennio Nano. International Journal of Applied Pharmaceutical Sciences and Research Volume 4 issue 1 January-March, 2019

Early Miscarriage: Morphological Data Useful to Clinical and Nosographic Classification.
Stefania Erra, Chiara Merlo. International Journal of Applied Pharmaceutical Sciences and Research Vol 4 Issue 2 April-June, 2019

A Rare Case of Male Breast Metastasis from Previously Removed Renal Cell Carcinoma.
Stefania Erra, Simone Lo Mastro, Silvio Modena International Journal of Applied Pharmaceutical Sciences and Research Vol 3 Issue 4 October-December, 2018

The appropriateness of pathological reports. S.Erra  MOJ Anatomy & Physiology, Volume 5 Issue 3 - 2018

On a Case of Inflammatory Myofibroblastic Tumor of the Urinary Bladder: An
Unexpected Diagnosis. Erra S* and Zambello L, Journal of Molecular Sciences Vol.2 No.2:8

Gastric Adenocarcinoma: Study of the Immunophenotypic Profile in View of the Latest Molecular Knowledge on Carcinogenesis. E. Guercio, S. Erra, Human Journals March 2018 Vol.:11, Issue:4

Placental Mesenchymal Dysplasia: report of a case and review of the literature.
S. Erra, A. Frigeri, A. Picozzi., Int. J. Adv. Res. 6(2), 342-347

Application of the PARIS SYSTEM in Thin-Prep urinary pathology report: Correlation with histology.
S. Erra, G. Campagnone, J. Rotella, M. Ferrari. Pathologica vol. 109 sept 2017, atti del congresso nazionale SIAPEC, poster

A novel approach towards FNAC with ultrasound guide and cytoassistance: utility of CYTOFOAM- CORE in differential diagnosis of nodular mass in parenchymatous superficial organs.
S. Erra, E. Mazzoni ,S. Modena, E. Carlon.  Pathologica vol. 109 sept 2017, atti del congresso SIAPEC, comunicazione orale

Perinatal Outcome and Multidisciplinary Management.
S. Erra. J Biomol Res Ther 2017, 6:2 DOI: 10.4172/2167-7956.1000e156

A Rare Case of Neck Metastasis from a Thyroid Papillary Carcinoma After Seventeen Years Diagnosed with US- Guided Fine Needle Aspiration Cytology.
S. Erra, A. Lancella, J Rotella, S. Ricotta, E. Mazzoni, E. Carlon. International Journal of Clinical Oncology and Cancer Research 2017; 2(5): 106-109 doi 10.11648/j.ijcocr.20170205

Strongyloides Stercoralis: an unexpected visitor in gastric mucosa.
S. Erra, M. Antoniolli, A. Delle Fave, E. Guercio, C. Gemme, International Journal of Recent Engineering Research and Development Volume No. 02 May 2017– Issue No. 05, ISSN: 2455-8761

A Novel Approach towards Fine Needle Aspiration Cytology with Ultrasound-Guide and Cyto-Assistance: Utility of Cytofoam- Core in Differential Diagnosis of Nodular Mass in Parenchymatous Superficial Organs. S.Erra. MOJ Anatomy & Physiology Volume 4 Issue 1 – 2017

Suspected Syndrome of Chromosome 22 Deletion in a Fetal Autopsy. S. Erra,  S. Ricotta, J.Rotella. Biomedical Sciences 2016; 2(6): 48-51 http://www.sciencepublishinggroup.com/j/bs
doi: 10.11648/j.bs.20160206.11

L’adenocarcinoma prostatico: un nuovo approccio diagnostico integrato finalizzato alla scelta terapeutica. A Delle Fave, S. Erra. Working Paper of Public Health nr. 06/2016 ISSN: 2279-9761


Ectopic Paratesticular Adrenal Gland in a Fetus: Fortuity or  Morphological Cues About the Cause of Death. S. Erra, S.Modena, G.Speranza International Journal of Clinical and Developmental Anatomy
2016; 2(2): 14-16 doi: 10.11648/j.ijcda.20160202.11 ISSN: 2469-7990 (Print); ISSN: 2469-8008 (Online)
   
Unusual pleural effusion from vulvar squamous cell carcinoma: report of a case and review of the literature. S. Erra, G. Patrucco, G. Speranza, S. Barbero, F. Brucculeri, G. Taverna. PATHOLOGICA 2016;108:148-150

Abrikossoff tumors with incorrect clinical diagnosis: report of two cases.
S. Erra, G. Speranza. Gazzetta Medica Italiana Archivio per le Scienze Mediche 2016 Marzo;175(3):118-20

Tumori stromali gastrointestinali: entità nosologica rara e modello esemplare per l’utilizzo di terapie personalizzate su base molecolare. C. Bettegazzi, S. Erra. Recenti Prog Med 2015; 106: 1-6

Standardized health educational project: a novel approach to improve formation in surgical pathology and cytopathology. S.Erra, S. Modena, V. Magnelli Pathologica Vol 106 sept 2014 poster atti congresso SIAPEC 

ll linfoma non Hodgkin primitivo a grandi cellule B del tratto genitale femminile: un caso clinico.
 S. Erra, F. Brucculeri, G. Taverna, S. Barbero.  NPT in oncologia 1/2014

Breast cancer metastatic in colonic mucosa: report of a case.
A Ortoleva, S. Erra. Working Paper of Public Health nr. 18/2013 ISSN: 2279-9761

ADENOCARCINOMA ACINARE PROSTATICO: valutazione dell’espressione di IGFR come possibile bersaglio per terapie molecolari mirate. A Sanzone, S. Erra. Working Paper of Public Health nr. 12/2013 ISSN: 2279-9761

A case of endocervical blue nevus. S. Erra, Working Paper of Public Health nr. 6/2013 ISSN: 2279-9761

Technical Options for inclusions in needle aspiration pathology and in selected serosal fluid.
S. Erra, S. Modena, E. Mazzoni, M. Butera. PATHOLOGICA, VOL. 104, GIUGNO 2012-07-23, comunicazione orale congresso SIAPEC

US Guided FINE NEEDLE ASPIRATION CYTOLOGY with Cyto-assistance  : experience of a peripheral hospital. S. Erra,  S.  Modena,  E.  Mazzoni,  N.  Manoiero,  S.  Barbero, L. Spagnolo, G.V. Salmaso
PATHOLOGICA, VOL. 104, GIUGNO 2012-07-23, comunicazione orale  congresso SIAPEC

Correlation between P16 immunopositivity and presence of  HPV-DNA  in selected PAP TESTS  with ASUS and LSIL diagnosis. M. PASTORMERLO, G. CAMPAGNONE, A. SANZONE, S. ROSSO, S. ERRA                                       PATHOLOGICA, VOL. 104, GIUGNO 2012-07-23, COMUNICAZIONE  CONGRESSO SIAPEC

BIOPSIA PLEURICA TC-GUIDATA CON AGO TRANCIANTE: ESPERIENZA DI UN CENTRO RADIODIAGNOSTICO IN UN’AREA AD ELEVATA INCIDENZA DI TUMORE RARO.
C. Tappero, S. Erra, E. Oppezzo, L. Spagnolo, G. Taverna, S. Barbero. 45- CONGRESSO NAZIONALE DI RADIOLOGIA MEDICA Jan-Feb 2012

Carcinoid in Meckel’s diverticulum: report of two case.  E. Ariotti, B. Fre, N. Manoiero, S. Erra .Farmaci, Vol. 10-n.5-6/2011 Sett-Dic. 2011

Serous cystadenofibroma of the Fallopian tube. Case report and literature review.
S. Erra, D. Costamagna. G. Chir. Vol.33-n.1/2, pp.31-33

Espressione dell’inibitore della protesi serinica mammario (Maspina) in casi selezionati di GIST: risultati e correlazione clinico-patologica.  S. Erra, M. Pastormerlo, M. Pavesi. Dante, Anno X, n.1 Aprile 2011

Breast cancer metastatic to the submandibular gland. Case report.
S. Erra, D. Costamagna. G Chir 2011Apr.32(4):194-8

GIST: DIFFERENTIAL DIAGNOSIS USING IMMUNOHISTOCHEMICAL PANEL OF ANTIBODIES IN SELECTED CASES.
S. Erra, S.Modena, M.Colombo ,E. Mazzoni, D. Costamagna, M. Pavesi.Pathologica vol.102(4) 2010, poster  congresso SIAPEC

Fine-needle cytology in nodular thyroid pathology. Cytopathologic and clinical correlations using SIAPEC recommended diagnostic categories. An italian peripheral hospital experience.
S. Erra, M. Colombo, S. Modena, C. Bocchio, M. Butera , M. Pastormerlo , M. Pavesi .Pathologica vol.102(4) 2010, comunicazione orale  congresso SIAPEC

Fine needle aspiration cytology for breast lesions and cytopathologic correlations. An Italian peripheral hospital experience of 440 cases (from 2000 to 2007). S. Erra, D, Costamagna. G Chir. 2010 Aug-Sep;31(8-9):404-408.

A rare case of extraskeletal osteosarcoma of the esophagus: an example of difficult diagnosis.
S. Erra, D. Costamagna, R. Durando.G Chir. 2010 Jan-Feb;31(1-2):24-27.

Acute abdomen in  the elderly. A peripheral general hospital experience.
D. COSTAMAGNA, N.S. PIPITONE FEDERICO, S. ERRA, M. TRIBOCCO, F. PONCINA, G. BOTTO, P. DEREGIBUS, A. ZULLO, G. SERVENTE, R. DURANDO. G Chir. 2009 Jun-Jul;30(6-7):315-322.

A case of leiomyoadenomatoid tumour of uterine serosa: speculations about differential diagnosis.
S. Erra, M. Pastormerlo, D. Costamagna, G. Gregori, M. Pavesi. BMJ Case Reports 25 Maggio 2009:bcr02.2009.1586

Intramuscular myxoma of the deltoid muscle : report of a case. D. Costamagna, S. Erra, R. Durando. BMJ 17 Marzo 2009:bcr08.2008.0678

Sporadic flat ileal adenocarcinoma: an intriguing challenge in the comprehension of a rare neoplasia and review of literature.
S. Erra, D. Costamagna, G. Botto, C. Gemme, R. Durando. G Chir. 2009 Mar; 30(3):87-92

Adenocarcinoma prostatico metastatico ai linfonodi del mesoretto. C. Gemme, S. Erra, D. Costamagna, N.S. Pipitone Federico, B. Demarchi, M. Pastormerlo. Questioni di clinica; esperienze cliniche in gastroenterologia sul territorio nazionale n.ro 1/2009 Mediprint s.r.l.

Correlazione citoistologica delle lesioni mammarie: casistica dell'Ospedale di Casale Monferrato.
S. Erra, M. Pastormerlo, D.Costamagna, R. Durando, M. Colombo, S. Modena, M. Pavesi. Pathologica Vol. 100-N.5, ottobre 2008, comunicazione orale a congresso SIAPEC

Small bowel intussusception secondary to inflammatory fibroid polyp of the ileum: report of a case.
D. Costamagna, S. Erra, A. Zullo, G. Servente, R. Durando. Chir Ital. 2008 Mar-Apr;60(2):323-7.

EGFR expression on surgical colorectal cancer specimens: clinical and histological features.
S. Erra, B. Demarchi, E. Mazzoni, F. Bresso, S. Modena, C. Bocchio, D. Costamagna, C. Gemme. Digestive and Liver disease vol.40 supl 1,marzo 2008 pagS120-12

Bravo capsule ph-metry: Technique of positioning.  B. Demarchi, S. Erra, M. Pastormerlo, M. Pavesi, C. Gemme.Digestive and Liver disease vol.38 supl 1,aprile 2006 pS52
   
Citologia su strato sottile dei versamenti. M. Pavesi, M. Pastormerlo, S. Erra. Pathologica vol.93(4) 2001, comunicazione orale a congresso SIAPEC

Neurocysticercosis: a case report. B. Carangelo, S. Erra, M.L. Del Basso De Caro, A. Bucciero, L. Vizioli, K. Panagiotopoulos, A. Cerillo J. Neurosurg. Sci. Vol. 45(1) 2001

Leiomyosarcoma of the maxilla: a case report. G. Savastano, M.D. Palombini, V. Muscariello, S. Erra J. Oral Maxillofacial Surg. Vol. 56(9) 1998

My name is Karthik Yadav Janga and I am currently working as Research Scientist in Novel Drug Delivery team at Bayer Pharmaceuticals (USA). I am writing this email in order to volunteer for joining the editorial board member and peer reviewer for your prestigious journal. I have published 23 research articles in renowned journals such as European Journal of Pharmaceutics and Biopharmaceutics and International Journal of Pharmaceutics etc, with over 273 citations. 8+ (academic and industrial) years research experiences in the field of pharmaceutics and drug delivery.

Research Interest: Drug delivery of NCEs, Protein, Peptides, Monoclonal antibodies

Grants: Research Scholar in NIH R01 grant

URL: https://scholar.google.com/citations?user=xZ4Z2wkAAAAJ&hl=en

List of Publications:

1.  Lipid nanoparticles of zaleplon for improved oral delivery by Box-Behnken design: optimization, in vitro and in vivo evaluation. N Dudhipala, KY Janga. Drug Dev Ind Pharm. 2017; 43(7): 1205-1214.

2.  Biopharmaceutical and Preclinical Studies of Zaleplon as Semisolid Dispersions with Self-emulsifying Lipid Surfactants for Oral Delivery. N Dudhipala, A Narala, D Suram, KY Janga. IJPSN. 2016; 9(1): 3102-3111. (Best Paper of the Year Award)

3.  Competence of raloxifene hydrochloride loaded liquisolid compacts for improved dissolution and intestinal permeation. DR Komala, KY Janga, R Jukanti, S Bandari, M Vijayagopal. J Drug Deliv Sci Technol. 2015; 30(A): 232-241. Main Author

4.  Gellan gum based sol-to-gel transforming system of natamycin transfersomes improves topical ocular delivery. KY Janga, A Tatke, N Dudhipala, SP Balguri, MM Ibrahim, DN Maria, MM Jablonski, S Majumdar. JPET. Mar 14, 2019. DOI: https://doi.org/10.1124/jpet.119.256446

5.  Ion-sensitive in situ hydrogels of natamycin bilosomes for enhanced and prolonged ocular pharmacotherapy: in vitro permeability, cytotoxicity and in vivo evaluation. KY Janga, A Tatke, SP Balguri, SP Lamichanne, MM Ibrahim, DN Maria, MM Jablonski, S Majumdar. Artif Cells Nanomed Biotechnol. 2018; 46(1): 1039-1050.

6.  Retina compatible interactions and effective modulation of blood ocular barrier P-gp activity by third-generation inhibitors improve the ocular penetration of loperamide. KY Janga, A Tatke, S Shukla, SP Lamichhane, B Avula, X Wang, MM Jablonski, IA Khan, S Majumdar. J Pharm Sci. 2018; 107(8): 2128-2135.

7.  Photostability Issues in Pharmaceutical Dosage Forms and Photostabilization. KY Janga, T King, N Ji, S Sarabu, G Shadambikar, S Sawant, P Xu, MA Repka, SN Murthy. AAPS PharmSciTech. 2018; 19(1): 48-59.

8.  P-glycoprotein restricts ocular penetration of loperamide across the blood-ocular barriers: a comparative study in Mdr1a knock-out and wild type sprague dawley rats. A Tatke, KY Janga, B Avula, X Wang, MM Jablonski, IA Khan, S Majumdar. AAPS PharmSciTech. 2018; 19(4): 1662-1671.

9.  In situ absorption and relative bioavailability studies of zaleplon loaded self-nanoemulsifying powders. KY Janga, R Jukanti, S Sunkavalli, A Velpula, S Bandari, P Kandadi, PR Veerareddy. J Microencapsul. 2013; 30(2): 161-172.

10.  Bioavailability enhancement of zaleplon via proliposomes: Role of surface charge. KY Janga, R Jukanti, A Velpula, S Sunkavalli, S Bandari, P Kandadi, PR Veerareddy. Eur J Pharm Biopharm. 2012; 80(2): 347-357.

11.  Melt-cast films significantly enhance triamcinolone acetonide delivery to the deeper ocular tissues. A Tatke, N Dudhipala, KY Janga, B Soneta, B Avula, S Majumdar. Pharmaceutics. 2019; 11(4): 158.

12.  In situ gel of triamcinolone acetonide-loaded solid lipid nanoparticles for improved topical ocular delivery: Tear kinetics and ocular disposition studies. A Tatke, N Dudhipala, KY Janga, SP Balguri, B Avula, M Jablonski, S Majumdar. Nanomaterials. 2019; 9(1): 33.

13. Comparative study of nisoldipine-loaded nanostructured lipid carriers and solid lipid nanoparticles for oral delivery: preparation, characterization, permeation and pharmacokinetic evaluation. N Dudhipala, KY Janga, T Gorre. Artif Cells Nanomed Biotechnol. 2018; 46(2): 616-625.

14. Micronized zaleplon delivery via orodispersible film and orodispersible tablets. P Manda, C Popescu, A Juluri, KY Janga, PR Kakulamarri, S Narishetty, SN Murthy, MA Repka. AAPS PharmSciTech. 2018; 19(3): 1358-1366.

15. Melt-cast noninvasive ocular inserts for posterior segment drug delivery. SP Balguri, GR Adelli, A Tatke, KY Janga, P Bhagav, S Majumdar. J Pharm Sci. 2017;106(12): 3515-3523.

16. Ocular disposition of ciprofloxacin from topical, PEGylated nanostructured lipid carriers: Effect of molecular weight and density of poly (ethylene) glycol. SP Balguri, GR Adelli, KY Janga, P Bhagav, S Majumdar. Int J Pharm. 2017; 529(1-2): 32-43.

17. Preparation and characterization of docetaxel self-nanoemulsifying powders (SNEPs): A strategy for improved oral delivery. S Sunkavalli, BB Eedara, KY Janga, A Velpula, R Jukanti, S Bandari. KOREAN J CHEM ENG. 2016; 33(3): 1115–1124.

18. Amoxycillin trihydrate floating-bioadhesive drug delivery system for eradication of Helicobacter pylori: Preparation, in vitro and ex vivo evaluation. N Dudhipala, A Narala, KY Janga, R Bomma. J Bioequiv Availab. 2016; 8(3): 118-124.

19. Enhanced dissolution efficiency of zaleplon solid dispersions via modified β-cyclodextrin molecular inclusion complexes. C Popescu, P Manda, A Juluri, KY Janga, M Cidda, SN Murthy. J. Pharm Pharm Scien. 2015; 1(1): 12-21.

20. Proliposome powders for enhanced intestinal absorption and bioavailability of raloxifene hydrochloride: effect of surface charge. A Velpula, R Jukanti, KY Janga, S Sunkavalli, S Bandari, P Kandadi, PR Veerareddy. Drug Dev Ind Pharm. 2013; 39(12): 1895-1906.

21. Enhanced intestinal absorption and bioavailability of raloxifene hydrochloride via lyophilized solid lipid nanoparticles. M Burraa, R Jukanti, KY Janga, S Sunkavalli, A Velpula, S Ampati, KN Jayaveera. ADV POWDER TECHNOL. 2013; 24(1): 393-402.

22. Development and characterization of ramipril loaded Solid self nanoemulsifying drug delivery system (SNEDDS) for improved oral delivery of lipophilic drugs. M Kasturi, S Agrawal, KY Janga. IJPBA. 2015; 6(6): 10-17.

23. Self nano emulsifying drug delivery system of ramipril: formulation and in vitro evaluation. M Kasturi, S Agrawal, KY Janga. Int J Pharm Pharm Sci. 2016; 8(4): 291-296.

In 2009, graduated from Tianjin Medical University with a Ph.D. in immunology. In the same year, began to work in the Institute of Ophthalmology of Tianjin Medical University, where worked as a basic researcher. In 2012, went to Germany for a one-year postdoctoral research. Up to now, has undertaken and completed three national and provincial-level projects, and published a total of 66 research papers.

Research Interest:

PSF signalling pathway

Ocular neovascularization disease

Experimental autoimmune uveitis (EAU)

Mesenchymal stem cell therapy

Dentritic cells maturation and migration

Grants:

•  as a project principal: PTB-associated splicing factor (PSF) functions as a repressor of HIF-1α-mediated VEGF gene transcription by recruitment of Hakai. (NSFC Granted NO. 81570872,2016-2019)

•  as a project principal: the molecular mechanism of transcriptional inhibitor PSF suppress Human retinal microvessal endothelial cells proliferation with IGF-1 stimulation. (NSFC Granted NO. 31100991,2012-2014)

•  as the participant :Identification the miRNAs related with the differentiation of ESCs into RPE cells and theit effect on JUN passway. (NSFC Granted NO. 30973255, 2011-2013)

List of Publications:

1.  Dong, L., Zhang, X., Fu, X., Zhang, X., Gao, X., Zhu, M., . . . Yang, J. (2011). PTB-associated splicing factor (PSF) functions as a repressor of STAT6-mediated Ig epsilon gene transcription by recruitment of HDAC1. J Biol Chem, 286(5), 3451-3459. doi:10.1074/jbc.M110.168377（co-first author）

2.  Liu, X., Dong, L., Zhang, X., Wang, B., Wang, X., Li, H., . . . Yang, J. (2011). Identification of p100 target promoters by chromatin immunoprecipitation-guided ligation and selection (ChIP-GLAS). Cell Mol Immunol, 8(1), 88-91. doi:10.1038/cmi.2010.47（co-first author）

3.  WB, L., MW, M., LJ, D., F, W., LX, C., biology, L. X. J. C., & therapy. (2011). MicroRNA-34a targets notch1 and inhibits cell proliferation in glioblastoma multiforme. 12(6), 477-483. (co-author)

4.  Li WB, Z. Y., Lu ZY,  Dong LJ,  Wang FE,  Dong R,  Li XR. (2012). Development of retinal pigment epi thelium from human parthenogenetic embryonic stem cells and microRNA signature. Invest. Ophthalmol. Vis. Sci., 53(9). doi:10.1167/iovs.12-8303  (co-author)

5.  LJ, Z., Y, Z., LJ, D., & ophthalmology, L. X. J. C. j. o. (2012). [Expression and function of microRNA in the eye]. 48(12), 1136-1140. (co-author)

6.  Tian, F., Dong, L., Zhou, Y., Shao, Y., Li, W., Zhang, H., & Wang, F. (2014). Rapamycin-Induced apoptosis in HGF-stimulated lens epithelial cells by AKT/mTOR, ERK and JAK2/STAT3 pathways. Int J Mol Sci, 15(8), 13833-13848. doi:10.3390/ijms150813833（co-first author）

7.   Wei, R., Dong, L., Xiao, Q., Sun, D., Li, X., & Nian, H. (2014). Engagement of Toll-like receptor 2 enhances interleukin (IL)-17(+) autoreactive T cell responses via p38 mitogen-activated protein kinase signalling in dendritic cells. Clin Exp Immunol, 178(2), 353-363. doi:10.1111/cei.12405（co-first author）

8.  Zhang, L., Dong, L., Liu, X., Jiang, Y., Zhang, L., Zhang, X., . . . Zhang, Y. (2014). alpha-Melanocyte-stimulating hormone protects retinal vascular endothelial cells from oxidative stress and apoptosis in a rat model of diabetes. PLoS One, 9(4), e93433. doi:10.1371/journal.pone.0093433 (co-author)

9.  Zhang, L., Zheng, H., Shao, H., Nian, H., Zhang, Y., Bai, L., . . . Zhang, X. (2014). Long-term therapeutic effects of mesenchymal stem cells compared to dexamethasone on recurrent experimental autoimmune uveitis of rats. Invest Ophthalmol Vis Sci, 55(9), 5561-5571. doi:10.1167/iovs.14-14788 (co-author)

10.  T, L., L, Z., B, Z., L, X., J, L., L, D., & reports, H. Y. J. O. (2015). Establishment and characterization of a cell line from human adenoid cystic carcinoma of the lacrimal glands and a nude mouse transplantable model. 33(6), 2797-2806. (co-author)

11.  Dong, L., Nian, H., Shao, Y., Zhang, Y., Li, Q., Yi, Y., . . . Li, X. (2015). PTB-associated splicing factor inhibits IGF-1-induced VEGF upregulation in a mouse model of oxygen-induced retinopathy. Cell Tissue Res, 360(2), 233-243. doi:10.1007/s00441-014-2104-5 (the first author)

12.  Shao, Y., Dong, L. J., Zhang, Y., Liu, H., Hu, B. J., Liu, J. P., & Li, X. R. (2015). Surgical induced astigmatism correlated with corneal pachymetry and intraocular pressure: transconjunctival sutureless 23-gauge versus 20-gauge sutured vitrectomy in diabetes mellitus. Int J Ophthalmol, 8(3), 528-533. doi:10.3980/j.issn.2222-3959.2015.03.16 （co-first author）

13.  Y, S., C, S., JT, W., B, D., LJ, D., AH, L., . . . medicine, e. (2015). Temporal and spatial changes in VEGF, αA- and αB-crystallin expression in a mouse model of oxygen-induced retinopathy. 8(3), 3349-3359. (co-author)

14.  PT, Z., LJ, Z., H, S., LL, B., B, Y., C, S., . . . ophthalmology, Z. X. J. I. j. o. (2016). Therapeutic effects of mesenchymal stem cells administered at later phase of recurrent experimental autoimmune uveitis. 9(10), 1381-1389. (co-author)

15.  W, L., L, D., M, M., B, H., Z, L., X, L., . . . therapy. (2016). Preliminary in vitro and in vivo assessment of a new targeted inhibitor for choroidal neovascularization in age-related macular degeneration. 10(undefined), 3415-3423.（co-first author）

16.  X, C., H, S., Y, Z., Q, X., C, S., L, D., . . . development. (2016). CD73 Pathway Contributes to the Immunosuppressive Ability of Mesenchymal Stem Cells in Intraocular Autoimmune Responses. 25(4), 337-346. (co-author)

17.  H, T., LY, H., F, T., LJ, D., & ophthalmology, Z. H. J. C. j. o. (2017). [Effects of SMP-30 overexpression on apoptosis of human lens epithelial cells induced by ultraviolet B irradiation]. 53(11), 835-841. (co-author)

18.  L, B., H, S., H, W., Z, Z., C, S., L, D., . . . reports, Z. X. J. S. (2017). Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis. 7(1), 4323. (co-author)

19.  X, W., Y, Z., L, Z., R, W., & vision, D. L. J. M. (2017). Comparison of fibrin glue and Vicryl sutures in conjunctival autografting for pterygium surgery. 23(undefined), 275-285. (co-author)

20.  L, D., X, C., H, S., L, B., X, L., & medicine, Z. X. J. C. m. (2018). Mesenchymal Stem Cells Inhibited Dendritic Cells Via the Regulation of STAT1 and STAT6 Phosphorylation in Experimental Autoimmune Uveitis. 17(7), 478-487. (the first author)

21.  T, M., LJ, D., XL, D., R, N., & ophthalmology, H. B. J. I. j. o. (2018). Research progress on the role of connective tissue growth factor in fibrosis of diabetic retinopathy. 11(9), 1550-1554.

22.  X, X., L, H., Y, L., X, L., R, S., X, L., & research, D. L. J. C. e. (2019). DL-3-n-butylphthalide Protected Retinal Müller Cells Dysfunction from Oxidative Stress. undefined(undefined), 1-9. (co-author)

23.  Y, S., LJ, D., Y, T., J, C., X, L., Q, C., . . . metabolism. (2019). miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy. 316(3), E443-E452. （co-first author）

24.  G, S., R, H., L, Z., X, S., K, H., L, D., . . . failure, K. Y. J. R. (2019). The effect of hemodialysis on ocular changes in patients with the end-stage renal disease. 41(1), 629-635. (co-author)

Research Interest: The nature of memory retained in the uterine myometrium that is responsible for recurrent loss of pregnancy ii. Regulation of small gproteins by oxidative and endoplasmic stress responses in pregnancies complicated by diabetes mellitus

Research Interest: My lab focuses on the involvement of the heme oxygenase (HO) system and nuclear receptors in metabolic diseases, which includes obesity and diabetes as well as cancer. The HO system maintains metabolic balance by signaling to biliverdin reductase that produces the antioxidant, bilirubin. My lab looks at the how HO, bilirubin, and nuclear receptors signal for balance in metabolic disorders. We are currently studying how bilirubin can aid the nutrient and lipid sensing nuclear receptors, the PPARs (PPAR alpha, PPAR gamma, and PPAR delta), in the maintenance of metabolic homeostasis. Other nuclear receptors are stress sensing, such as the glucocorticoid receptors (GRalpha and GR beta), which regulate the immune system balance and glucose production during times of stress. Altogether, we look at the PPARs and GRs regulation of the balance of lipids and glucose as well as maintain growth of cancer cells.

Research Interest: Diabetic foot, cutaneous complication of diabetes, lipodystrophy, cutaneous manifestation of thyroid diseases, Cushing disease, adrenal insufficiency, and adrenal hyperplasia.

Research Interest: Mineral metabolism and metabolic bone disease, in particular osteoporosis

Research Interest: Primary: Kidney (patho-)physiology Secondary: Diabetes mellitus, oxidative stress, ion transport

Research Interest: Endocrinology, endocrine disorders, developmental endocrinology, endocrine pathophysiology/issues, endocrine disorders complications treatment/management.

Research Interest: My research interests are to reveal the functional relevance of glucagon-like peptides (GLP-1/2) and receptors in the control of energy balance and glucose homeostasis

Research Interest: His research has concentrated on how physical, environmental, and emotional stress affects the hormonal responses of the endocrine system; in particular, focusing on dysfunctions and dis-regulations that develop in the system from stress exposure, that ultimately can compromise physiological responses and adaptations

Research Interest: Aldosterone, mineralocorticoids, mineralocorticoid receptor, gene expression, miRNAs, animal models, microarrays, renin-angiotensin system, steroid hormones, nuclear receptors, hypertension, intracellular signaling.

Research Interest: Diabetes- obesity-Inflammation, thyroid cancer and Neuroendocrine Tumors

Research Interest: Thyroid disease and in particular thyroid nodules and thyroid cancer, as well as postgraduate medical education..

Research Interest: Gestational diabetes and fetal programming, Gender aspects of obesity Gender aspects of metabolic syndrome, Gender aspects of type 2 diabetes, Gender aspects of type 1 diabetes/autoimmunity, Gender aspects of insulin resistance and beta cell function: Changes in pathogenesis of and interaction with different disease processes, Gender aspects of inflammation, adipokines, endothelial dysfunction

Research Interest: Diabetes type 1 and 2, insulin resistance, skeletela muscle, cardiovascular risk in diabetes

Research Interest: Research has been focused on the understanding of the mechanisms of the development of Peeclampsia, the most common cause of retarded fetal development.

Research Interest: An ongoing study on the assessment of renal function in the course of diabetes mellitus

Research Interest: Diabetes ,osteoporosis,thyroid ,and adrenal pathophysiology.

Research Interest: Diabetes experimental and clinical and gastroenterology and neuroendocrine tumors

Research Interest: Physiology and pharmacology of nociceptors by means of capsaicin to open new horizons for development nociceptor targeted analgesic/anti-inflammatory agents and to reveal sensory-efferent dual functions of capsaicin-sensitive nociceptors

Research Interest: Molecular imaging, receptor scintigraphies, SPECT-CT, PET-CT

Research Interest: Comparative endocrinology with focus on neuroendocrine regulation and signal transduction for pituitary hormone secretion and gene expression in fish models, especially for growth hormone, somatolactin and gonadotropinsFunctional interactions & underlying post-receptor signaling of adipokines (e.g., leptin & adiponectin) and novel feeding peptides (e.g., spexin & apelin) with pituitary hormones in fish pituitary cells

Research Interest: Molecular Imaging in Oncology with SPECT/CT, PET/CT and PET/MR.

He is a member of the European Society for Paediatric Endocrinology (ESPE) and the Società Italiana di Endocrinologia e Diabetologia Pediatrica (SIEDP), among others. research focus is the investigation of the pathophysiology of insulin resistance during childhood growth and development, the metabolic syndrome, and endocrinological disorders in children with rare diseases and genetic syndromes and disorders.

Research Interest: Andrological Sciences.

Research Interest: Tuberculosis, hospital infections, HIV, pediatric infectious Disease

Research Interest: Autoimmunity, autoimmune thyroid disease, thyrotropin receptor, thyrotropin autoantibodies, thyroglobulin autoantibodies, thyroperoxidase autoantibodies.

Research Interest: Role of autoimmunity in the pathogenesis of thyroid diseases. Growth factors and thyroid cancer. Prevention of endemic goiter

Research Interest: His particular interests are in clinical research methodology, data science, and genomic medicine, also having published, as co-author, several papers in scientific journals such as JAMA, Archives of Internal Medicine, Hypertension, Diabetes Care, Journal of Clinical Endocrinology and Metabolism

Research Interest: Hormone metabolism, Lipid metabolism, Bone and mineral metabolism Endocrine pharmacology, Cardiovascular endocrinology, Diabetes mellitus, Obesity and metabolic syndrome

Research Interest: Reproductive science, Antioxidant potential of some peptides: oxytocin, melatonin, kisspeptin, Neurosicence, Ischemia/reperfusion injury, Reproductive science, Antioxidant potential of some peptides: oxytocin, melatonin, kisspeptin, NeurosicenceIschemia/reperfusion injury

Research Interest: Sleep apnea research, but especially in sleep apnea related with endocrine disorders, testosterone disorders in sleep apnea patients

Research Interest: Endocrinology, diabetes, obesity, genetics, children

Health Sciences,Medicine,Immunology, Allergology and Rheumatology

Research Interest: Menopause and oestrogen replacement therapy (ERT) Metabolic syndrome and metabolic effects of estrogens Phytoestrogens, SERM and Endocrine Disruptors Polycystic ovary syndrome (PCOS) Polymorphisms of the oestrogen receptor geneAnti-inflammatory and anti-atherogenic properties of estrogens

Research Interest: Genetic disorder, splicing mutations, Cornelia de Lange Syndrome, HMG-CoA lyase deficiency, HMG-CoA synthase deficiency

Research Interest: Sports Injuries.,Sports and Health.,Sarcopenia.,Sports nutrition

Research Interest: Osteoporosis and obesity

Research Interest: Role of Sex Hormones in Various Pathophysiologies with specific relevance to Women’s Health,role of hormone metabolism in the pathophysiology of estrogen action

Research Interest: Prostate Cancer, Molecular Epidemiology, Pharmacogenomic studies, Metabolic syndrome, Endocrine-Related Cancer, Urolithiasis, Andrology, Male Erectile dysfunction

Research Interest: Angiotensin II effects on renal dopamine metabolism using in vitro models and different techniques like pharmacological approaches, kinetic studies, enzymatic activities and radiolabel markers. For my postdoctoral work, I expanded my research area and studied the relationship between atrial natriuretic peptide and renal dopamine system and its impact on sodium handling. For this purpose we employed an in vivo model to evaluate this interaction on urinary parameters and used molecular techniques to demonstrate the involvement of different tubular transports

Research Interest: Have expertise in the field of Endocrine Physiology and Metabolism, more specifically working with metabolic programming in critical stages of life development and its consequences on the body weight composition and pancreatic islets function. Actually, the field of studies is undernutrition in early life and the development of obesity and type 2 diabetes later in life.

Research Interest: Environmental toxins and prostate development,  Endocrine disruptors and urogenital development, Carcinogenesis rodent models for prostate cancer, Chemoprevention in rodent models of prostate carcinogenesis and human cancer cells (in vitro) – AKT pathway evaluation, Reproductive Endocrinology and Infertility, Effects of endocrine disruptors in human Sertoli cells (in vitro) with focus in adhesion molecules, AR pathway and DNA methylation

Research Interest: Pathophysiological mechanisms to cardiometabolic diseases.

Research Interest: General Physiology, Endocrine Physiology, Neuroendocrine Regulation of Body Weight, Epidemiology of Obesity and Diabetes, Endocrinology, Exercise Effect Evaluation

Research Interest: Obesity and diabetes mainly involving the early stages of life (pregnancy and lactation), research is related to the concept DoHAD (Developmental Origins of Health and Disease, areas of metabolic diseases and physical exercise.

Research Interest: Urologia, Urological Surgery, Andrologia, Clinical Medicine

Research Interest: Osteoporosis, Autophagy, Osteocyte, Mechanism.

Research Interest: Preparation and tissue fabrication of novel biomedical materials;Novel bioreactor technology and its application, Control of expansion and differentiation of stem cells, Construction, numerical simulation and optimization of dynamic culture systems, Regulation of active component of traditional Chinese medicine on proliferation and differentiation of stem cells

Research Interest: Thyroid,diabetes and other endocrine diseases

Research Interest: The novel functions of calcineurin B subunit (CnB) in the activation of innate immunity and in cancer treatment. We have identified the integrin αM as a new receptor of CnB on macrophage and revealed how this receptor mediates CnB-triggered anti-tumor activity. We also showed that CnB protein can synergize with inteferon-γ to skew tumor-associated macrophages (TAMs) to an anti-tumor phenotype (M1 phenotype) and to enhance inteferon-γ- mediated tumoricidal activity. So far, I mainly focus on the molecular mechanisms of necroptosis (a new form of programmed cell death). We are trying to reveal new modulators in the regulation of necroptotic pathway, and to reveal the roles and mechanisms of necroptosis in tumorgenisis and metastasis

Research Interest: Diabetes, Adrenal Insufficiency, Evidence-Based Medicine in Endocrinology

Research Interest: Understand the role of stroma in tumorigenesis: Studying the molecular mechanisms and signaling transduction induced by the interaction with the extracellular matrix components. Effect of tumoral fibrosis on the effect and distribution of radiopharmaceuticals. Analysis of the integrin activation mechanisms and its relation with cell differentiation

Research Interest: Biochemical aspects of endocrinology- biochemical aspects of bone metabolism- biochemical aspects of kidney diseases- lipid and lipoprotein metabolism- electrophoresis technique.

Research Interest: Diabetes,  transplantation,  pancreatic islets culture, influence of microorganism on onset of the diabetes, human microbiom.