International Journal of Clinical Endocrinology and Metabolism Submit Manuscript

    Introduction

    • Volume/IssueClick here
    • Review ProcessDouble Blind
      • Publication lead time3 - 4 weeks
      • Indexing statusYes; Purview
      • Manuscript Processing ChargesClick here
      • Submission ChargesNo
      • Waiver policy for APCYes
      • Language of Full TextEnglish
      • Full-text formats availablePDF, HTML
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    • Articles digitally archived in PORTICO
    • Permanent article identifierDOI (Digital Object Identifier) We provide DOI to all published papers to facilitate higher citation and classification of articles.
      Peertechz Publisher ID: 10.17352
    • Type of LicenseCreative Commons
      • Open AccessYes; Policy
      • Does the author retain unrestricted copyright?Yes
      • Does the author retain publishing rights?Yes
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    Editor-in-Chief

    Malgorzata Gabriela WASNIEWSKA

    Malgorzata Gabriela WASNIEWSKA
    University of Messina, Italy
    Email: [email protected]
    Tel: +393286522425
    Fax: +390902212134

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    Executive Editors

    Sze May Ng
    Consultant Paaediatric Endocrinologist , Honorary Senior Lecturer
    Southport and Ormskirk Hospitals NHS Trust
    University of Liverpool
    United Kingdom
    IJCEM

    Dr May Ng MBBS (Hons) FHEA FRCPCH MSc LLM PhD

    Dr May Ng holds a dual accreditation specialist qualification in General Paediatrics and Paediatric Endocrinology & Diabetes. She is based in Southport and Ormskirk NHS Trust and is the Associate Medical Director. She was previously Clinical Director for Paediatrics from 2012-2016.  She has an Honorary Senior Lecturer position at the Institute of Translational Medicine, University of Liverpool. She completed her undergraduate degree under full scholarship in Sydney, Australia and undertook her paediatric training in Australia and in the United Kingdom (UK). She was the recipient of the UK Medical Research Council Fellowship in 2006 and completed further training to obtain a Masters and PhD degree in paediatric endocrinology and diabetes. Dr Ng also holds a Master of Laws degree and is active in medicolegal work.

    Dr Ng has held over £300,000 in research grants and is an active researcher in paediatric endocrinology and diabetes. She has produced a book chapter and over 100+ publications (50 peer reviewed research papers, 45 as first/senior author) including three Cochrane reviews and has presented at more than 100+ scientific meetings.

    Research Interest: puberty, thyroid, diabetes , adrenal

    URL: www.paedsdoc.co.uk

    PROFESSIONAL MEMBERSHIPS AND ROLES:

    Fellow of the Royal College of Paediatrics and Child Health (FRCPCH)

    Fellow of the Higher Education Academy (FHEA)

    Member of the European Society of Paediatric Endocrinology (ESPE)

    Committee member of European Society of Paediatric Endocrinology Online Learning

    Member of the National Institute of Clinical Excellence (NICE) Adoption and Impact Programme Reference Panel

    Member of the National Steering Group for Children and Young People’s Diabetes Peer Review

    Diabetes Officer of the British Society of Paediatric Endocrinology and Diabetes (BSPED)

    Assessor for the Royal College of Paediatrics and Child Health ST7/START

    Committee Member of the RCPCH Paediatricians in Medical Management

    RCPCH CSAC Training Advisor for Endocrinology and Diabetes


    PROFESSIONAL QUALIFICATIONS:

    CCST, Certificate of Completion of Specialist Training: (1) General Paediatrics and (2) Paediatric Endocrinology and Diabetes, General Medical Council UK

    FRCPCH, Royal College of Paediatrics and Child Health, UK

    DCH, Royal College of Paediatrics and Child Health, UK

    FHEA, Fellow of the Higher Education Academy, UK

    MBBS (Honours) University of Sydney, Australia

    Master of Medical Science (Child Health, Diabetes and Endocrinology) University of Liverpool

    PhD (Child Health) University of Liverpool

    Master in Laws , University of Liverpool</xml> <

    Grant details:

    Winner of 2015 Diabetes Quality in Care (QiC) award
    Finalist Commended 2017 Diabetes Team of the year Diabetes Quality in Care (QiC) award
    Pride Awards 2015 Team of the Year Southport & Ormskirk NHS Trust
    Highly Commended Diabetes Team of the Year 2015 BMJ awards
    Finalist HSJ Clinical Leader of the year 2015
    Finalist in the UK Asian Woman of Achievement Award
    Newborn Appeal Grant 2011
    Best Research Abstract Award 2010 BSPED UK
    Newborn Appeal Grant 2007
    MRC Fellowship 2006 Medical Research Council, UK
    University Prize for Paediatrics,    University of Sydney, Australia

    Number of Publications: 50

    1.    Ng SM, Turner MA, Avula S. Ultrasound measurements of thyroid gland volume at 36 weeks corrected gestational age in extreme preterm infants born before 28 weeks gestation. European Thyroid Journal 2017.

    2.    Apperley L, Ng SM. Socioeconomic Deprivation, Household Education and Employment are Associated With Increased Hospital Admissions and Poor Glycemic Control in Children With Type 1 Diabetes Mellitus. Review of Diabetic Studies 2017

    3.    Ng SM. Digital Footprints: Steps towards transformation in paediatric diabetes. Journal of MHealth 2017, March ow.ly/g6Um30aYCZU

    4.    Ng SM, Stepien K. Glucocorticoid replacement regimens in the treatment of 21-hydroxylase deficiency congenital adrenal hyperplasia (Protocol) published Cochrane Database of Systematic Reviews 2017, Issue 1. Art. No CD012517. DOI: 10.1002/14651858.CD012517

    5.    Ng SM, Edge J. Hyperglycaemic Hyperosmolar State (HHS) in children: A practical guide to management. Paediatrics and Child Health Journal 2017 http://dx.doi.org/10.1016/j.paed.2017.01.002

    6.    Ng SM, Soni A, Didi M. Neonatal Pituitary-Thyroid Axis Dysregulation with Combined Thyroid Hormone and Thyrotropin Resistance in Infant with Trisomy 21 and Maternal Subclinical Hypothyroidism. J Neonatal Biol 2016 5:4 DOI: 10.4172/2167-0897.1000243

    7.     Ng SM, Agwu JC, Dwan K. A systematic review and meta-analysis of Synacthen tests for assessing hypothalamic-pituitary-adrenal insufficiency in children. Arch Dis Child 2016 :1–7. doi:10.1136/archdischild-2015-308925

    8.    Ng SM, Turner M. The Importance of Risk Stratification and Management of Newborn Babies of Women with a History of Graves’ disease. Int J Clin Endocrinol Metab 2016, 2(1): 001-004
    9.    Soni A, Agwu JC, Kershaw M, Edge J, Wright N, Ng SM. Management of children with type 1 diabetes during illness: a national survey. Postgrad Med J 2015 doi:10.1136/postgradmedj-2015-133786

    10.    Ng SM, Vizard M. The great enabler: how technology is helping to improve patient outcomes in paediatric diabetes. British Journal of Diabetes and Vascular Disease 2015;15:86-88

    11.    Soni A, Ng SM. Type 1 and Type 2 diabetes in children and young people: updated NICE guidance. Practical Diabetes 2015;32:281-282

    12.    Ng SM. Improving patient outcomes with technology and social media in paediatric diabetes. BMJ Quality Improvement Reports 2015; 4(1) DOI:10.1136/bmjquality.u209396.w3846 (1)

    13.    Ng SM, Watson G, Turner MA, Newland P and Weindling AM. Do maternal factors influence neonatal thyroid status in the extreme premature infant? The Journal of Maternal-Fetal & Neonatal Medicine 2014:26:1-11.

    14.    Agwu C, Ng SM, Edge DA, Wright. Care of children and young people with diabetes who require surgery. Diabetes Care for Children and Young People 2014:3:106-110

    15.    Ng SM, Soni A. Intensive diabetes management and goal setting are key aspects of improving metabolic control in children and young people with Type 1 diabetes mellitus. World Journal of Diabetes 2014: 5(6): 877-881 DOI: http://dx.doi. org/10.4239/wjd.v5.i6.877

    16.    Ng SM, Finnigan L, Connellan L, Caitriona Kerinan, Coward S. Improving paediatric diabetes care with the use of an integrated paediatric electronic diabetes information management system and routine uploading of blood glucose meters and insulin pumps in outpatient clinics. Archive of Disease in Childhood 2014; 99:1059 doi:10.1136/archdischild-2014-307021

    17.    Ng SM, Mariguddi S, Coward S, Middleton H. Successful implementation of a paediatric community home nursing service as a model of service delivery in acute paediatric care. British Journal of Nursing 2014: 23 (4):209-212.

    18.    Ng SM, Turner MA, Watson G, Victor S, Isherwood DM, Newland P, Didi M and Weindling AM. Is dopamine an iatrogenic disruptor of thyroid and cortisol function in the extremely premature infant? Advances in Endocrinology 2014; DOI:http://dx.doi.org/10.1155/2014/973184

    19.    Soni A, Shaw EJ, Natarajan A, Ng SM. Children with Type 1 Diabetes mellitus developing concurrent autoimmune disease are not at risk of worsening metabolic control or growth impairment. Practical Diabetes 2014: 31(6):243-246

    20.    Ng SM, Turner MA, Didi M, Parkes L, Tietze A, Atkinson J, Sluming V and Weindling AM. Effect of thyroxine on brain microstructure in extremely premature babies: magnetic resonance imaging findings from the TIPIT study. Pediatric Radiology 2014:44 (8):987-96

    21.    Ng SM, Balmuri S. Review of insulin treatment in stress related hyperglycaemia in children without pre-existing diabetes. Acta Paediatrica 2013 doi:10.1111/apa.12442
    22.    Ng SM, Turner MA, Victor S, M Didi, C Gamble, D Manning, R Gupta, P Settle. P Newland and Weindling AM. An explanatory randomised placebo-controlled trial of thyroxine supplementation in extreme preterm Infants < 28>
    23.    Murphy A, Martin P, Jukka C, Menon A, Ng SM. Recurrent primary paediatric herpetic whitlow of the big toe. BMJ Case Reports 2013 doi:10.1136/bcr-2013-008598

    24.    Murphy C and Ng SM. Institution of multiple daily insulin regimen compared with twice daily pre-mixed insulin regimen for children with Type 1 Diabetes Mellitus. American Journal of Clinical Medicine Research 2013  1 (1). doi: 10.12691/ajcmr-1-1-2

    25.    Ng SM, Drury JA, Turner MA, M Didi, Victor S, Paul Newland, Weindling AM. A Novel Method of Collection of Saliva for Estimation of Steroid Levels in Extremely Premature Infants. Acta Paediatrica 2013:102 (4): 356-9

    26.    Gangadharan A, Hanumanthaiah H, Ng SM.  The Use of Iodine as First Line Therapy in Graves' Disease Complicated with Neutropenia at First Presentation in a Paediatric Patient. British Journal of Medicine and Medical Research, 3(2): 324-328, 2013

    27.    Hanumanthaiah H, Gangadharan A, Ng SM. Continuous insulin infusion therapy for acute stress hyperglycemia secondary to asthma exacerbation in a paediatric patient. Journal of Diabetes Research and Clinical Metabolism 2012: http://dx.doi.org/10.7243/2050-0866-1-19

    28.    Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M.  Multivariate analysis of factors that affect neonatal screening thyrdois stimulating hormone. Journal of Pediatric Endocrinology and Metabolism 2011, 24: 727-732

    29.    Hussain M, Cheri J, Khalid M, Matouk Z, Ng SM, Chanderasekaran S, Didi M, Blair J. Growth monitoring still has a place in selected populations of children. BMJ Case Reports 2011; doi:10.1136/bcr.01.2010.2640

    30.    Ng SM, Weindling MA. The impact of networks on clinical trials in the United Kingdom . Trials 2009, 10:100

    31.    Ng SM, Turner MA, Gamble C, M Didi, Victor S, Malamateniou C, Parkes L, Tietze A, Gregory L,Sluming V, Abernethy L and Weindling AM. TIPIT: A Randomised Controlled Trial of Thyroxine in Preterm Infants under 28 weeks Gestation: Magnetic Resonance Imaging and Magnetic Resonance Angiography Protocol. BMC Pediatrics 2008, 8:26

    32.    Ng SM. Hypothyroxinemia of prematurity: cause, diagnosis and management. Expert Review of Endocrinology & Metabolism 2008, 3: 453-462

    33.    Ng SM, Dhullipala A, Weindling AM. High versus low dose of initial thyroid hormone replacement for congenital hypothyroidism. Cochrane Database of Systemic Reviews 2008, Issue 1

    34.    Ng SM, Turner MA, Gamble, Didi M, Victor S, Weindling AM. TIPIT: A Randomised controlled trial of thyroxine in preterm infants born under 28 weeks gestation. Trials 2008, 9: 17

    35.    Ng SM, Wong SC, Isherwood DM, Didi M. Biochemical severity of thyroid ectopia in congenital hypothyroidism demonstrates sexual dimorphism. European Journal of Endocrinology 2007, 156: 49-53

    36.    Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M.  There is a delay in screening premature infants for congenital hypoithyroidism. Archives of Disease in Childhood Fetal Neonatal Ed 2006, 91: F465-466

    37.    Ng SM, May JE, Emmerson AJB. Continuous insulin infusion in hyperglycemic ELBW infants: An evaluation of treatment response. Biology of the Neonate 2005, 4: 269-272

    38.    Ng SM, Kumar Y, Cody D, Didi M and Smith CS. The gonadotrophins response to GnRH test is not a predictor of neurological lesion in girls with central precocious puberty. Journal of Pediatric Endocrinology and Metabolism 2005, 18: 849-852

    39.    Ng SM, Wong SC, Isherwood DM, Smith CS, Didi M. Multivariate analysis on factors affecting suppression of thyroid stimulating hormone in treated congenital hypothyroidism. Hormone Research 2004, 20: 245-251

    40.    Wong SC, Ng SM, Didi M. Children with congenital hypothyroidism are at risk of adult obesity due to early adiposity rebound. Clinical Endocrinology 2004, 61: 441-6

    41.    Ng SM, Wong SC, Didi M. Head circumference and linear growth during the first 3 years in treated congenital hypothyroidism in relation to aetiology and initial biochemical severity. Clinical Endocrinology 2004, 61: 155-9

    42.    Chalameau M, Hadjiaathanasiou C, Ng SM, Cassio A, Mul D, Cisternino M, Partsch CJ, Theodoris C, Didi M, Cacciari E, Oostdijk W, Borghesi A, Sippell WG, Breart G, Brauner R. How to select girls with precocious puberty for brain imaging? An evidence based approach: EUROPUB study. A multicentre trial. Journal of Pediatrics 2003, 143: 445-450

    43.    Ng SM, Jones AP. Drug therapies for reducing gastric acidity in people with cystic fibrosis. Cochrane Collaboration, Cochrane Library 2003, Issue 2

    44.    Ng SM, Kumar Y, Cody D, Didi M and Smith CS. Cranial MRI scans are indicated in all girls with central precocious puberty. Archives of Disease in Childhood 2003, 88:  414-418

    45.    Cody D, Ng SM, Didi M and Smith CS. The differing outcomes of hyperthyrotropinemia. Journal of Paediatric Endocrinology and Metabolism 2003, 16: 375-378

    46.    Ng SM, Khurana R, Hughes U, Manning D. Is prolonged use of computer games a risk factor for deep venous thrombosis in children? Clinical Medicine 2003, 6: 593-594

    47.    Ng SM, Toh EM and Sherrington CA. Clinical predictors of abnormal computed tomography scans in paediatric head injury. Journal of Paediatrics and Child Health 2002, 38: 388-392

    48.    Ng SM, Ariffin WA, Lin HP, Chan LL and Chin YM. Clinical features and treatment outcome of children with myeloid antigen coexpression in B-lineage acute lymphoblastic leukemia. Journal of Tropical Paediatrics 2000, 46: 73-78

    49.    Ng SM, Lin HP, Ariffin WA, Lam SK and Chan LL. Age, sex, hemoglobin and white cell count at diagnosis are important prognostic factors in children with acute lymphoblastic leukemia treated with BFM-type protocol. Journal of Tropical Paediatrics 2000, 46:  338-343

    50.    Ng SM, Ariffin WA, Lin HP and Chan LL. Presenting features and treatment outcome of 78 Malaysian children with neuroblastoma. Southeast Asian Journal of Tropical Medicine and Public Health 1999, 30: 149-153



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    Editorial Board

    Kamoi Kyuzi
    Medical Doctor
    Educator and Administration Birth information
    Japan
    IJCEM

    Research Interest: Reproductive science, Antioxidant potential of some peptides: oxytocin, melatonin, kisspeptin, Neurosicence, Ischemia/reperfusion injury, Reproductive science, Antioxidant potential of some peptides: oxytocin, melatonin, kisspeptin, NeurosicenceIschemia/reperfusion injury

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    Dorota Szydlarska
    Ph.D
    Department of Family Medicine
    Medical University of Warsaw
    Poland
    IJCEM

    I was born in 1980 in Minsk Mazowiecki, I graduated from high school in 1999, and started at the medical school in the same year. In 2005, I obtained my medical degree. In 2012, I obtained the title of doctor of medical sciences, defending my doctoral thesis in the field of endocrinology. In 2013, I obtained the title of specialist in internal medicine, in 2016 in the field of nuclear medicine, in 2019 in the field of family medicine, then in 2021 in the field of endocrinology. I also completed postgraduate studies in organization and management in health care. I also work at Warsaw Medical University in Department of Family Medicine and I has been educating medical students since 2007. Since 2011, I have been associated with one medical facility, initially starting as an assistant, currently holding a managerial position. I actively participate in Polish and international meetings and conferences. I am constantly increasing my publication output and am currently involved in several medical projects. In the coming year I hope to publish three books in the field of endocrinology and family medicine. I participated in the research programs LanroNET, a non-interventional, prospective study to assess the resource utilization and cost of lanreotide autogel 120 mg in Polish patients with neuroendocrine tumors – results of interim analysis and Lipidogram 2015 & Lipidogen 2016.

    Research Interest: endocrinology, family medicine

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    Anna Ciampolillo
    Department of Emergency and Organ Transplantation
    University of Bari
    Italy
    IJCEM

    Research Interest: Role of autoimmunity in the pathogenesis of thyroid diseases. Growth factors and thyroid cancer. Prevention of endemic goiter

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    Paola Di Carlo
    Department of Infectious Disease
    University of Palermo Palermo
    Italy
    IJCEM

    Research Interest: Tuberculosis, hospital infections, HIV, pediatric infectious Disease

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    Domenico Rubello
    Professor
    Department of Nuclear Medicine
    University of Padua
    Italy
    IJCEM

    Research Interest: Molecular Imaging in Oncology with SPECT/CT, PET/CT and PET/MR.

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    Dubravka Jurisic-Erzen
    Professor
    University of Rijeka
    Croatia
    IJCEM

    Research Interest: Diabetes type 1 and 2, insulin resistance, skeletela muscle, cardiovascular risk in diabetes

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    Mathias Z Strowski
    Professor
    Department of Internal Medicine
    Elbland Clinic
    Germany
    IJCEM

    Research Interest: Diabetes experimental and clinical and gastroenterology and neuroendocrine tumors

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    Wellerson Rodrigo Scarano
    Associate Professor
    Department of Human Embriology
    Sao Paulo State University
    Brazil
    IJCEM

    Research Interest: Environmental toxins and prostate development,  Endocrine disruptors and urogenital development, Carcinogenesis rodent models for prostate cancer, Chemoprevention in rodent models of prostate carcinogenesis and human cancer cells (in vitro) – AKT pathway evaluation, Reproductive Endocrinology and Infertility, Effects of endocrine disruptors in human Sertoli cells (in vitro) with focus in adhesion molecules, AR pathway and DNA methylation

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    GianLuca Colussi
    Department of Experimental and Clinical Medical Sciences
    University of Udine
    Italy
    IJCEM

    Research Interest: His particular interests are in clinical research methodology, data science, and genomic medicine, also having published, as co-author, several papers in scientific journals such as JAMA, Archives of Internal Medicine, Hypertension, Diabetes Care, Journal of Clinical Endocrinology and Metabolism

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    Dasheng Lin
    Orthopaedic Center of Peoples Liberation Army
    Xiamen University
    China
    IJCEM

    Research Interest: Osteoporosis, Autophagy, Osteocyte, Mechanism.

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    Behrouz D Salehian
    Associate Professor
    Department of Diabetes, Endocrinology and Metabolism
    Beckman Research Institute
    USA
    IJCEM

    Research Interest: Diabetes- obesity-Inflammation, thyroid cancer and Neuroendocrine Tumors

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    Chandra Miryala
    Wayne State University
    USA
    IJCEM

    Research Interest: Endocrinology, endocrine disorders, developmental endocrinology, endocrine pathophysiology/issues, endocrine disorders complications treatment/management.

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    Rene Rodriguez Gutierrez
    Professor
    Department of Medicine
    Autonomous University of New Leon
    Mexico
    IJCEM

    Research Interest: Diabetes, Adrenal Insufficiency, Evidence-Based Medicine in Endocrinology

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    Erika Patricia A Vega
    Researcher
    Nuclear Research National Institute
    Mexico
    IJCEM

    Research Interest: Understand the role of stroma in tumorigenesis: Studying the molecular mechanisms and signaling transduction induced by the interaction with the extracellular matrix components. Effect of tumoral fibrosis on the effect and distribution of radiopharmaceuticals. Analysis of the integrin activation mechanisms and its relation with cell differentiation

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    Zhenyi Su
    Department of Biochemistry and Molecular Biology
    Southeast University
    China
    IJCEM

    Research Interest: The novel functions of calcineurin B subunit (CnB) in the activation of innate immunity and in cancer treatment. We have identified the integrin αM as a new receptor of CnB on macrophage and revealed how this receptor mediates CnB-triggered anti-tumor activity. We also showed that CnB protein can synergize with inteferon-γ to skew tumor-associated macrophages (TAMs) to an anti-tumor phenotype (M1 phenotype) and to enhance inteferon-γ- mediated tumoricidal activity. So far, I mainly focus on the molecular mechanisms of necroptosis (a new form of programmed cell death). We are trying to reveal new modulators in the regulation of necroptotic pathway, and to reveal the roles and mechanisms of necroptosis in tumorgenisis and metastasis

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    DOI Logo 10.17352/ijcem.000066

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