International Journal of Clinical Endocrinology and Metabolism Submit Manuscript

    Introduction

    • Volume/IssueClick here
    • Review ProcessDouble Blind
      • Publication lead time3 - 4 weeks
      • Indexing statusYes; Purview
      • Manuscript Processing ChargesClick here
      • Submission ChargesNo
      • Waiver policy for APCYes
      • Language of Full TextEnglish
      • Full-text formats availablePDF, HTML
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    • Articles digitally archived in PORTICO
    • Permanent article identifierDOI (Digital Object Identifier) We provide DOI to all published papers to facilitate higher citation and classification of articles.
      Peertechz Publisher ID: 10.17352
    • Type of LicenseCreative Commons
      • Open AccessYes; Policy
      • Does the author retain unrestricted copyright?Yes
      • Does the author retain publishing rights?Yes
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    Editor-in-Chief

    Malgorzata Gabriela WASNIEWSKA

    Malgorzata Gabriela WASNIEWSKA
    University of Messina, Italy
    Email: [email protected]
    Tel: +393286522425
    Fax: +390902212134

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    Executive Editors

    Sze May Ng
    Consultant Paaediatric Endocrinologist , Honorary Senior Lecturer
    Southport and Ormskirk Hospitals NHS Trust
    University of Liverpool
    United Kingdom
    IJCEM

    Dr May Ng MBBS (Hons) FHEA FRCPCH MSc LLM PhD

    Dr May Ng holds a dual accreditation specialist qualification in General Paediatrics and Paediatric Endocrinology & Diabetes. She is based in Southport and Ormskirk NHS Trust and is the Associate Medical Director. She was previously Clinical Director for Paediatrics from 2012-2016.  She has an Honorary Senior Lecturer position at the Institute of Translational Medicine, University of Liverpool. She completed her undergraduate degree under full scholarship in Sydney, Australia and undertook her paediatric training in Australia and in the United Kingdom (UK). She was the recipient of the UK Medical Research Council Fellowship in 2006 and completed further training to obtain a Masters and PhD degree in paediatric endocrinology and diabetes. Dr Ng also holds a Master of Laws degree and is active in medicolegal work.

    Dr Ng has held over £300,000 in research grants and is an active researcher in paediatric endocrinology and diabetes. She has produced a book chapter and over 100+ publications (50 peer reviewed research papers, 45 as first/senior author) including three Cochrane reviews and has presented at more than 100+ scientific meetings.

    Research Interest: puberty, thyroid, diabetes , adrenal

    URL: www.paedsdoc.co.uk

    PROFESSIONAL MEMBERSHIPS AND ROLES:

    Fellow of the Royal College of Paediatrics and Child Health (FRCPCH)

    Fellow of the Higher Education Academy (FHEA)

    Member of the European Society of Paediatric Endocrinology (ESPE)

    Committee member of European Society of Paediatric Endocrinology Online Learning

    Member of the National Institute of Clinical Excellence (NICE) Adoption and Impact Programme Reference Panel

    Member of the National Steering Group for Children and Young People’s Diabetes Peer Review

    Diabetes Officer of the British Society of Paediatric Endocrinology and Diabetes (BSPED)

    Assessor for the Royal College of Paediatrics and Child Health ST7/START

    Committee Member of the RCPCH Paediatricians in Medical Management

    RCPCH CSAC Training Advisor for Endocrinology and Diabetes


    PROFESSIONAL QUALIFICATIONS:

    CCST, Certificate of Completion of Specialist Training: (1) General Paediatrics and (2) Paediatric Endocrinology and Diabetes, General Medical Council UK

    FRCPCH, Royal College of Paediatrics and Child Health, UK

    DCH, Royal College of Paediatrics and Child Health, UK

    FHEA, Fellow of the Higher Education Academy, UK

    MBBS (Honours) University of Sydney, Australia

    Master of Medical Science (Child Health, Diabetes and Endocrinology) University of Liverpool

    PhD (Child Health) University of Liverpool

    Master in Laws , University of Liverpool</xml> <

    Grant details:

    Winner of 2015 Diabetes Quality in Care (QiC) award
    Finalist Commended 2017 Diabetes Team of the year Diabetes Quality in Care (QiC) award
    Pride Awards 2015 Team of the Year Southport & Ormskirk NHS Trust
    Highly Commended Diabetes Team of the Year 2015 BMJ awards
    Finalist HSJ Clinical Leader of the year 2015
    Finalist in the UK Asian Woman of Achievement Award
    Newborn Appeal Grant 2011
    Best Research Abstract Award 2010 BSPED UK
    Newborn Appeal Grant 2007
    MRC Fellowship 2006 Medical Research Council, UK
    University Prize for Paediatrics,    University of Sydney, Australia

    Number of Publications: 50

    1.    Ng SM, Turner MA, Avula S. Ultrasound measurements of thyroid gland volume at 36 weeks corrected gestational age in extreme preterm infants born before 28 weeks gestation. European Thyroid Journal 2017.

    2.    Apperley L, Ng SM. Socioeconomic Deprivation, Household Education and Employment are Associated With Increased Hospital Admissions and Poor Glycemic Control in Children With Type 1 Diabetes Mellitus. Review of Diabetic Studies 2017

    3.    Ng SM. Digital Footprints: Steps towards transformation in paediatric diabetes. Journal of MHealth 2017, March ow.ly/g6Um30aYCZU

    4.    Ng SM, Stepien K. Glucocorticoid replacement regimens in the treatment of 21-hydroxylase deficiency congenital adrenal hyperplasia (Protocol) published Cochrane Database of Systematic Reviews 2017, Issue 1. Art. No CD012517. DOI: 10.1002/14651858.CD012517

    5.    Ng SM, Edge J. Hyperglycaemic Hyperosmolar State (HHS) in children: A practical guide to management. Paediatrics and Child Health Journal 2017 http://dx.doi.org/10.1016/j.paed.2017.01.002

    6.    Ng SM, Soni A, Didi M. Neonatal Pituitary-Thyroid Axis Dysregulation with Combined Thyroid Hormone and Thyrotropin Resistance in Infant with Trisomy 21 and Maternal Subclinical Hypothyroidism. J Neonatal Biol 2016 5:4 DOI: 10.4172/2167-0897.1000243

    7.     Ng SM, Agwu JC, Dwan K. A systematic review and meta-analysis of Synacthen tests for assessing hypothalamic-pituitary-adrenal insufficiency in children. Arch Dis Child 2016 :1–7. doi:10.1136/archdischild-2015-308925

    8.    Ng SM, Turner M. The Importance of Risk Stratification and Management of Newborn Babies of Women with a History of Graves’ disease. Int J Clin Endocrinol Metab 2016, 2(1): 001-004
    9.    Soni A, Agwu JC, Kershaw M, Edge J, Wright N, Ng SM. Management of children with type 1 diabetes during illness: a national survey. Postgrad Med J 2015 doi:10.1136/postgradmedj-2015-133786

    10.    Ng SM, Vizard M. The great enabler: how technology is helping to improve patient outcomes in paediatric diabetes. British Journal of Diabetes and Vascular Disease 2015;15:86-88

    11.    Soni A, Ng SM. Type 1 and Type 2 diabetes in children and young people: updated NICE guidance. Practical Diabetes 2015;32:281-282

    12.    Ng SM. Improving patient outcomes with technology and social media in paediatric diabetes. BMJ Quality Improvement Reports 2015; 4(1) DOI:10.1136/bmjquality.u209396.w3846 (1)

    13.    Ng SM, Watson G, Turner MA, Newland P and Weindling AM. Do maternal factors influence neonatal thyroid status in the extreme premature infant? The Journal of Maternal-Fetal & Neonatal Medicine 2014:26:1-11.

    14.    Agwu C, Ng SM, Edge DA, Wright. Care of children and young people with diabetes who require surgery. Diabetes Care for Children and Young People 2014:3:106-110

    15.    Ng SM, Soni A. Intensive diabetes management and goal setting are key aspects of improving metabolic control in children and young people with Type 1 diabetes mellitus. World Journal of Diabetes 2014: 5(6): 877-881 DOI: http://dx.doi. org/10.4239/wjd.v5.i6.877

    16.    Ng SM, Finnigan L, Connellan L, Caitriona Kerinan, Coward S. Improving paediatric diabetes care with the use of an integrated paediatric electronic diabetes information management system and routine uploading of blood glucose meters and insulin pumps in outpatient clinics. Archive of Disease in Childhood 2014; 99:1059 doi:10.1136/archdischild-2014-307021

    17.    Ng SM, Mariguddi S, Coward S, Middleton H. Successful implementation of a paediatric community home nursing service as a model of service delivery in acute paediatric care. British Journal of Nursing 2014: 23 (4):209-212.

    18.    Ng SM, Turner MA, Watson G, Victor S, Isherwood DM, Newland P, Didi M and Weindling AM. Is dopamine an iatrogenic disruptor of thyroid and cortisol function in the extremely premature infant? Advances in Endocrinology 2014; DOI:http://dx.doi.org/10.1155/2014/973184

    19.    Soni A, Shaw EJ, Natarajan A, Ng SM. Children with Type 1 Diabetes mellitus developing concurrent autoimmune disease are not at risk of worsening metabolic control or growth impairment. Practical Diabetes 2014: 31(6):243-246

    20.    Ng SM, Turner MA, Didi M, Parkes L, Tietze A, Atkinson J, Sluming V and Weindling AM. Effect of thyroxine on brain microstructure in extremely premature babies: magnetic resonance imaging findings from the TIPIT study. Pediatric Radiology 2014:44 (8):987-96

    21.    Ng SM, Balmuri S. Review of insulin treatment in stress related hyperglycaemia in children without pre-existing diabetes. Acta Paediatrica 2013 doi:10.1111/apa.12442
    22.    Ng SM, Turner MA, Victor S, M Didi, C Gamble, D Manning, R Gupta, P Settle. P Newland and Weindling AM. An explanatory randomised placebo-controlled trial of thyroxine supplementation in extreme preterm Infants < 28>
    23.    Murphy A, Martin P, Jukka C, Menon A, Ng SM. Recurrent primary paediatric herpetic whitlow of the big toe. BMJ Case Reports 2013 doi:10.1136/bcr-2013-008598

    24.    Murphy C and Ng SM. Institution of multiple daily insulin regimen compared with twice daily pre-mixed insulin regimen for children with Type 1 Diabetes Mellitus. American Journal of Clinical Medicine Research 2013  1 (1). doi: 10.12691/ajcmr-1-1-2

    25.    Ng SM, Drury JA, Turner MA, M Didi, Victor S, Paul Newland, Weindling AM. A Novel Method of Collection of Saliva for Estimation of Steroid Levels in Extremely Premature Infants. Acta Paediatrica 2013:102 (4): 356-9

    26.    Gangadharan A, Hanumanthaiah H, Ng SM.  The Use of Iodine as First Line Therapy in Graves' Disease Complicated with Neutropenia at First Presentation in a Paediatric Patient. British Journal of Medicine and Medical Research, 3(2): 324-328, 2013

    27.    Hanumanthaiah H, Gangadharan A, Ng SM. Continuous insulin infusion therapy for acute stress hyperglycemia secondary to asthma exacerbation in a paediatric patient. Journal of Diabetes Research and Clinical Metabolism 2012: http://dx.doi.org/10.7243/2050-0866-1-19

    28.    Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M.  Multivariate analysis of factors that affect neonatal screening thyrdois stimulating hormone. Journal of Pediatric Endocrinology and Metabolism 2011, 24: 727-732

    29.    Hussain M, Cheri J, Khalid M, Matouk Z, Ng SM, Chanderasekaran S, Didi M, Blair J. Growth monitoring still has a place in selected populations of children. BMJ Case Reports 2011; doi:10.1136/bcr.01.2010.2640

    30.    Ng SM, Weindling MA. The impact of networks on clinical trials in the United Kingdom . Trials 2009, 10:100

    31.    Ng SM, Turner MA, Gamble C, M Didi, Victor S, Malamateniou C, Parkes L, Tietze A, Gregory L,Sluming V, Abernethy L and Weindling AM. TIPIT: A Randomised Controlled Trial of Thyroxine in Preterm Infants under 28 weeks Gestation: Magnetic Resonance Imaging and Magnetic Resonance Angiography Protocol. BMC Pediatrics 2008, 8:26

    32.    Ng SM. Hypothyroxinemia of prematurity: cause, diagnosis and management. Expert Review of Endocrinology & Metabolism 2008, 3: 453-462

    33.    Ng SM, Dhullipala A, Weindling AM. High versus low dose of initial thyroid hormone replacement for congenital hypothyroidism. Cochrane Database of Systemic Reviews 2008, Issue 1

    34.    Ng SM, Turner MA, Gamble, Didi M, Victor S, Weindling AM. TIPIT: A Randomised controlled trial of thyroxine in preterm infants born under 28 weeks gestation. Trials 2008, 9: 17

    35.    Ng SM, Wong SC, Isherwood DM, Didi M. Biochemical severity of thyroid ectopia in congenital hypothyroidism demonstrates sexual dimorphism. European Journal of Endocrinology 2007, 156: 49-53

    36.    Ng SM, Wong SC, Chakkrapani E, Rahman F, Newland P, Isherwood DM, Didi M.  There is a delay in screening premature infants for congenital hypoithyroidism. Archives of Disease in Childhood Fetal Neonatal Ed 2006, 91: F465-466

    37.    Ng SM, May JE, Emmerson AJB. Continuous insulin infusion in hyperglycemic ELBW infants: An evaluation of treatment response. Biology of the Neonate 2005, 4: 269-272

    38.    Ng SM, Kumar Y, Cody D, Didi M and Smith CS. The gonadotrophins response to GnRH test is not a predictor of neurological lesion in girls with central precocious puberty. Journal of Pediatric Endocrinology and Metabolism 2005, 18: 849-852

    39.    Ng SM, Wong SC, Isherwood DM, Smith CS, Didi M. Multivariate analysis on factors affecting suppression of thyroid stimulating hormone in treated congenital hypothyroidism. Hormone Research 2004, 20: 245-251

    40.    Wong SC, Ng SM, Didi M. Children with congenital hypothyroidism are at risk of adult obesity due to early adiposity rebound. Clinical Endocrinology 2004, 61: 441-6

    41.    Ng SM, Wong SC, Didi M. Head circumference and linear growth during the first 3 years in treated congenital hypothyroidism in relation to aetiology and initial biochemical severity. Clinical Endocrinology 2004, 61: 155-9

    42.    Chalameau M, Hadjiaathanasiou C, Ng SM, Cassio A, Mul D, Cisternino M, Partsch CJ, Theodoris C, Didi M, Cacciari E, Oostdijk W, Borghesi A, Sippell WG, Breart G, Brauner R. How to select girls with precocious puberty for brain imaging? An evidence based approach: EUROPUB study. A multicentre trial. Journal of Pediatrics 2003, 143: 445-450

    43.    Ng SM, Jones AP. Drug therapies for reducing gastric acidity in people with cystic fibrosis. Cochrane Collaboration, Cochrane Library 2003, Issue 2

    44.    Ng SM, Kumar Y, Cody D, Didi M and Smith CS. Cranial MRI scans are indicated in all girls with central precocious puberty. Archives of Disease in Childhood 2003, 88:  414-418

    45.    Cody D, Ng SM, Didi M and Smith CS. The differing outcomes of hyperthyrotropinemia. Journal of Paediatric Endocrinology and Metabolism 2003, 16: 375-378

    46.    Ng SM, Khurana R, Hughes U, Manning D. Is prolonged use of computer games a risk factor for deep venous thrombosis in children? Clinical Medicine 2003, 6: 593-594

    47.    Ng SM, Toh EM and Sherrington CA. Clinical predictors of abnormal computed tomography scans in paediatric head injury. Journal of Paediatrics and Child Health 2002, 38: 388-392

    48.    Ng SM, Ariffin WA, Lin HP, Chan LL and Chin YM. Clinical features and treatment outcome of children with myeloid antigen coexpression in B-lineage acute lymphoblastic leukemia. Journal of Tropical Paediatrics 2000, 46: 73-78

    49.    Ng SM, Lin HP, Ariffin WA, Lam SK and Chan LL. Age, sex, hemoglobin and white cell count at diagnosis are important prognostic factors in children with acute lymphoblastic leukemia treated with BFM-type protocol. Journal of Tropical Paediatrics 2000, 46:  338-343

    50.    Ng SM, Ariffin WA, Lin HP and Chan LL. Presenting features and treatment outcome of 78 Malaysian children with neuroblastoma. Southeast Asian Journal of Tropical Medicine and Public Health 1999, 30: 149-153



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    Editorial Board

    Zhenyi Su
    Department of Biochemistry and Molecular Biology
    Southeast University
    China
    IJCEM

    Research Interest: The novel functions of calcineurin B subunit (CnB) in the activation of innate immunity and in cancer treatment. We have identified the integrin αM as a new receptor of CnB on macrophage and revealed how this receptor mediates CnB-triggered anti-tumor activity. We also showed that CnB protein can synergize with inteferon-γ to skew tumor-associated macrophages (TAMs) to an anti-tumor phenotype (M1 phenotype) and to enhance inteferon-γ- mediated tumoricidal activity. So far, I mainly focus on the molecular mechanisms of necroptosis (a new form of programmed cell death). We are trying to reveal new modulators in the regulation of necroptotic pathway, and to reveal the roles and mechanisms of necroptosis in tumorgenisis and metastasis

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    Raluca Mihaela Bercea
    Pulmonologist specialist
    Helse Fonna Hospital
    Norway
    IJCEM

    Research Interest: Sleep apnea research, but especially in sleep apnea related with endocrine disorders, testosterone disorders in sleep apnea patients

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    Sabrina Grassiolli
    Professor
    Department of Biological Sciences
    Ponta Grossa State University
    Brazil
    IJCEM

    Research Interest: General Physiology, Endocrine Physiology, Neuroendocrine Regulation of Body Weight, Epidemiology of Obesity and Diabetes, Endocrinology, Exercise Effect Evaluation

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    Przemysław Witek
    Department of Endocrinology and Diabetes
    Military Institute of Medicine
    Poland
    IJCEM
    More Info.
    Rodrigo Mello Gomes
    Department of Cell Biology and Genetics
    Garden Universitario
    Brazil
    IJCEM

    Research Interest: Obesity and diabetes mainly involving the early stages of life (pregnancy and lactation), research is related to the concept DoHAD (Developmental Origins of Health and Disease, areas of metabolic diseases and physical exercise.

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    Júlio Cezar de Oliveira
    Professor
    Department of Human Physiology
    Universidade Federal de Mato Grosso
    Brazil
    IJCEM

    Research Interest: Have expertise in the field of Endocrine Physiology and Metabolism, more specifically working with metabolic programming in critical stages of life development and its consequences on the body weight composition and pancreatic islets function. Actually, the field of studies is undernutrition in early life and the development of obesity and type 2 diabetes later in life.

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    Dominik Rachon
    Head
    Department of Clinical and Experimental Endocrinology
    Medical University Of Gdansk
    Poland
    IJCEM

    Research Interest: Menopause and oestrogen replacement therapy (ERT) Metabolic syndrome and metabolic effects of estrogens Phytoestrogens, SERM and Endocrine Disruptors Polycystic ovary syndrome (PCOS) Polymorphisms of the oestrogen receptor geneAnti-inflammatory and anti-atherogenic properties of estrogens

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    Beatriz Puisac Uriol
    Professor
    Department of Physiology
    University of Zaragoza
    Spain
    IJCEM

    Research Interest: Genetic disorder, splicing mutations, Cornelia de Lange Syndrome, HMG-CoA lyase deficiency, HMG-CoA synthase deficiency

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    Domenico Rubello
    Professor
    Department of Nuclear Medicine
    University of Padua
    Italy
    IJCEM

    Research Interest: Molecular Imaging in Oncology with SPECT/CT, PET/CT and PET/MR.

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    Alexandra Kautzky-Willer
    Professor
    Department of Internal Medicine
    Medical University of Vienna
    Austria
    IJCEM

    Research Interest: Gestational diabetes and fetal programming, Gender aspects of obesity Gender aspects of metabolic syndrome, Gender aspects of type 2 diabetes, Gender aspects of type 1 diabetes/autoimmunity, Gender aspects of insulin resistance and beta cell function: Changes in pathogenesis of and interaction with different disease processes, Gender aspects of inflammation, adipokines, endothelial dysfunction

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    Francesco Latrofa
    Assistant Professor
    Department of Endocrinology
    University of Pisa
    Italy
    IJCEM

    Research Interest: Autoimmunity, autoimmune thyroid disease, thyrotropin receptor, thyrotropin autoantibodies, thyroglobulin autoantibodies, thyroperoxidase autoantibodies.

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    Efstratios Moralidis
    Department of Nuclear Medicine
    Aristotle University Medical School
    Greece
    IJCEM

    Research Interest: An ongoing study on the assessment of renal function in the course of diabetes mellitus

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    Dasheng Lin
    Orthopaedic Center of Peoples Liberation Army
    Xiamen University
    China
    IJCEM

    Research Interest: Osteoporosis, Autophagy, Osteocyte, Mechanism.

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    GianLuca Colussi
    Department of Experimental and Clinical Medical Sciences
    University of Udine
    Italy
    IJCEM

    Research Interest: His particular interests are in clinical research methodology, data science, and genomic medicine, also having published, as co-author, several papers in scientific journals such as JAMA, Archives of Internal Medicine, Hypertension, Diabetes Care, Journal of Clinical Endocrinology and Metabolism

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    Sai Prasad Pydi
    Research Assistant
    Department of Bioorganic Chemistry
    National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    USA
    IJCEM
    Department of Bioorganic  Chemistry,
    Diabetes, Obesity,
    Receptor Pharmacology Gpcrs and Metabolism
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