Research Interest: Cardiovascular diseases, Endothelial function, Hypertension, Diabetes, Renin-angiotensin-system

Research Interest: Her Clinical and Research Interest Focuses on Diabetes Management, Cardiovascular Risk, Flow Cytometry-Based Study of Endothelial Dysfunction, Novel Therapy for Type 2 Diabetes, Clinical Nutrition and Mediterranean Diet

Research Interest: Dietetics Applied to Bariatric Ssurgery; Clinical Impact of Bariatric Surgery on Patient’s Body Composition (Fat Mass and Fat-Free Mass) and Resting Metabolic Rate; Pre- and Post-Operative Treatment of Micronutrient Deficiencies in Patients that Underwent Bariatric Surgery.

Research Interest: Metabolomics Studies, Particularly on the Fetal-Neonatal Nutrition and Prevention of Chronic Diseases in Adults such as Obesity, Diabetes and Metabolic Syndrome.

Research Interest: Clinical Cardiology; Clinical Pharmacology; Cardiovascular Physiology; Arterial Hypertension; Blood Pressure Monitoring; Telemedicine.

2 Parati G, Ravogli A, Bragato R, OMBONI S, Mutti E, Mancia G. Clinical and hemodynamic effects of celiprolol in essential hypertension. J Cardiovasc Pharmacol 1989;7:S14-21.
3 Mancia G, Groppelli A, Casadei R, OMBONI S, Mutti E, Parati G. Cardiovascular effects of smoking. Clin Exp Hypertens A 1990;5:917-29.
4 Parati G, Castiglioni P, Di Rienzo M, OMBONI S, Pedotti A, Mancia G. Sequential spectral analysis of 24-hour blood pressure and pulse interval in humans. Hypertension 1990;4:414-21.
5 Groppelli A, OMBONI S, Parati G, Mancia G. Blood pressure and heart rate response to repeated smoking before and after beta-blockade and selective alpha 1 inhibition. J Hypertens Suppl 1990;5:S35-40.
6 Mutti E, Trazzi S, OMBONI S, Parati G, Mancia G. Effect of placebo on 24-h non-invasive ambulatory blood pressure. J Hypertens 1991;4:361-4.
7 Parati G, Trazzi S, Ravogli A, Casadei R, OMBONI S, Mancia G. Methodological problems in evaluation of cardiovascular effects of stress in humans. Hypertension 1991;4 Suppl:III50-5.
8 Groppelli A, OMBONI S, Ravogli A, Villani A, Parati G, Mancia G. Validation of the SpaceLabs 90202 and 90207 devices for ambulatory blood pressure monitoring by comparison with intra-arterial resting and ambulatory measurements. J Hypertens Suppl 1991;6:S334-5.
9 Trazzi S, OMBONI S, Mutti E, Parati G, Zanchetti A, Mancia G. Acute modulation of arterial compliance in mild essential hypertension. J Hypertens Suppl 1991;6:S110-1.
10 Zito M, Parati G, OMBONI S, Cervone C, Ulian L, D'Aviero M, Abate G, Mancia G. Effect of ageing on blood pressure variability. J Hypertens Suppl 1991;6:S328-9.
11 OMBONI S, Ravogli A, Parati G, Zanchetti A, Mancia G. Prognostic value of ambulatory blood pressure monitoring. J Hypertens Suppl 1991;3:S25-8.
12 Parati G, Groppelli A, OMBONI S, Trazzi S, Frattola A, Mancia G. Testing the accuracy of blood pressure monitoring devices in ambulatory conditions. J Hypertens Suppl 1991;8:S7-9.
13 Di Rienzo M, Parati G, Castiglioni P, OMBONI S, Ferrari AU, Ramirez AJ, Pedotti A, Mancia G. Role of sinoaortic afferents in modulating BP and pulse-interval spectral characteristics in unanesthetized cats. Am J Physiol 1991;6 Pt 2:H1811-8.
14 Groppelli A, Giorgi DM, OMBONI S, Parati G, Mancia G. Persistent blood pressure increase induced by heavy smoking. J Hypertens 1992;5:495-9.
15 Giannattasio C, Cattaneo BM, OMBONI S, Seravalle G, Bolla G, Turolo L, Morganti A, Grassi G, Zanchetti A, Mancia G. Sympathomoderating influence of benazepril in essential hypertension. J Hypertens 1992;4:373-8.
16 Mancia G, OMBONI S, Parati G, Trazzi S. Twenty-four hour blood pressure monitoring and end-organ damage. Blood Press Suppl 1992;1:38-41.
17 Mancia G, Frattola A, OMBONI S, Parati G, Rarogli A. Twenty-four-hour blood pressure and antihypertensive treatment. Blood Press Suppl 1992;1:44-5.
18 Parati G, OMBONI S, Di Rienzo M, Frattola A, Albini F, Mancia G. Twenty-four hour blood pressure variability:clinical implications. Kidney Int Suppl 1992;37:S24-8.
19 Groppelli A, OMBONI S, Parati G, Mancia G. Evaluation of noninvasive blood pressure monitoring devices Spacelabs 90202 and 90207 versus resting and ambulatory 24-hour intra-arterial blood pressure. Hypertension 1992;2:227-32.
20 Trazzi S, OMBONI S, Santucciu C, Parati G, Mancia G. Variability in arterial diameter and compliance:compliance modulation reserve. J Hypertens Suppl 1992;6:S41-3.
21 Villani A, Parati G, Groppelli A, OMBONI S, Di Rienzo M, Mancia G. Noninvasive automatic blood pressure monitoring does not attenuate nighttime hypotension. Evidence from 24 h intraarterial blood pressure monitoring. Am J Hypertens 1992;10:744-7.
22 Mancia G, OMBONI S, Ravogli A, Frattola A, Villani A. Ambulatory blood pressure monitoring. Drugs 1992;1:17-22.
23 OMBONI S, Frattola A, Parati G, Ravogli A, Mancia G. Clinical value of blood pressure measurements:focus on ambulatory blood pressures. Am J Cardiol. 1992;12:4D-8D.
24 Mancia G, OMBONI S, Parati G, Trazzi S, Mutti E. Limited reproducibility of hourly blood pressure values obtained by ambulatory blood pressure monitoring:implications for studies on antihypertensive drugs. J Hypertens 1992;12:1531-5.
25 OMBONI S, Ravogli A, Mancia G. Ambulatory blood pressure monitoring and antihypertensive treatment. J Hum Hypertens 1992;2:S9-13.
26 Mancia G, Giannattasio C, OMBONI S. Ambulatory blood pressure monitoring and antihypertensive treatment. Eur Heart J 1992;G:43-7.
27 Mancia G, De Cesaris R, Fogari R, Lattuada S, Montemurro G, Palombo C, Porcellati C, Ranieri G, Tettamanti F, Verdecchia P, Marelli C, OMBONI S, Ravogli A, Zanchetti A, for the Italian Trandolapril Study Group. Evaluation of the antihypertensive effect of once-a-day trandolapril by 24-hour ambulatory blood pressure monitoring. The Italian Trandolapril Study Group. Am J Cardiol 1992;70:60D-66D.
28 Laurent S, Hayoz D, Trazzi S, Boutouyrie P, Waeber B, OMBONI S, Brunner HR, Mancia G, Safar M. Isobaric compliance of the radial artery is increased in patients with essential hypertension. J Hypertens 1993;1:89-98.
29 Mancia G, OMBONI S, Parati G, Santucciu C, Trazzi S, Ulian L. Clinical value of ambulatory blood pressure monitoring. Am J Hypertens 1993;3 Pt 2:9S-13S.
30 Parati G, di Rienzo M, OMBONI S, Castiglioni P, Frattola A, Mancia G. Spectral analysis of 24 h blood pressure recordings. Am J Hypertens 1993;6 Pt 2:188S-193S.
31 Mancia G, OMBONI S, Parati G, Sega R, Trazzi S. Ambulatory blood pressure monitoring in the design of studies on antihypertensive drug efficacy. Am J Hypertens 1993;6 Pt 2:233S-235S.
32 OMBONI S, Parati G, Frattola A, Mutti E, Di Rienzo M, Castiglioni P, Mancia G. Spectral and sequence analysis of finger blood pressure variability. Comparison with analysis of intra-arterial recordings. Hypertension. 1993;1:26-33.

Zanchetti A, Bianchi L, Amigoni S, OMBONI S, Villani A, Ravogli A. Antihypertensive effects of nifedipine gastrointestinal therapeutic system on clinic and ambulatory blood pressure in essential hypertensives. Italian GITS Study Group. J Hypertens Suppl 1993;5:S334-5.
34 Pomidossi G, Saino A, Perondi R, Gregorini L, Alessio P, Rimini A, OMBONI S, Zanchetti A, Mancia G. Impairment of the arterial baroreflex during symptomatic and silent myocardial ischemia in humans. J Am Coll Cardiol 1993;7:1866-72.
35 Ravogli A, OMBONI S, De Cesaris R, Fogari R, Lattuada S, Montemurro G, Palombo C, Porcellati C, Ranieri G, Tettamanti C. Twenty-four-hour ambulatory blood pressure monitoring and antihypertensive treatment:focus on ACE inhibitors. J Cardiovasc Pharmacol 1994;1:S15-9.
36 Mancia G, OMBONI S, Parati G, Ravogli A, Sega R, Ulian L. Ambulatory blood pressure monitoring in the diagnosis of hypertension and evaluation of antihypertensive drug efficacy. Blood Press Suppl 1994;2:20-2.
37 Mancia G, Frattola A, Groppelli A, OMBONI S, Parati G, Ulian L, Villani A. Blood pressure reduction and end-organ damage in hypertension. J Hypertens Suppl 1994;8:S35-41.
38 Parati G, Ravogli A, Mutti E, Santucciu C, OMBONI S, Mancia G. Ambulatory blood pressure monitoring in the evaluation of antihypertensive drugs. J Hypertens Suppl 1994;8:S9-15.
39 OMBONI S, Smit AA, Wieling W. Twenty four hour continuous non-invasive finger blood pressure monitoring:a novel approach to the evaluation of treatment in patients with autonomic failure. Br Heart J 1995;3:290-2.
40 Mancia G, OMBONI S, Parati G, Ravogli A, Villani A, Zanchetti A. Lack of placebo effect on ambulatory blood pressure. Am J Hypertens 1995;3:311-5.
41 Mancia G, OMBONI S, Ravogli A, Parati G, Zanchetti A. Ambulatory blood pressure monitoring in the evaluation of antihypertensive treatment:additional information from a large data base. Blood Press 1995;3:148-56.
42 Parati G, Di Rienzo M, OMBONI S, Ulian L, Mancia G. Blood pressure variability over 24 hours:its different components and its relationship to the arterial baroreflex. J Sleep Res 1995;S1:21-29.
43 Mancia G, Giannattasio C, Turrini D, Grassi G, OMBONI S. Structural cardiovascular alterations and blood pressure variability in human hypertension. J Hypertens Suppl 1995;2:S7-14.
44 OMBONI S, Parati G, Zanchetti A, Mancia G. Calculation of trough:peak ratio of antihypertensive treatment from ambulatory blood pressure:methodological aspects. J Hypertens 1995;10:1105-12.
45 OMBONI S, Ravogli A, Villani A, Mancia G. Permanent blood pressure control over the 24 h by trandolapril. Am J Hypertens 1995;10 Pt 2:71S-74S.
46 Thijs L, Dabrowska E, Clement D, Fagard R, Laks T, Mancia G, O'Brien E, OMBONI S, Parati G, Staessen J, et al. Diurnal blood pressure profile in older patients with isolated systolic hypertension. The SYST-EUR Investigators. J Hum Hypertens 1995;11:917-24.
47 Parati G, Ulian L, Santucciu C, OMBONI S, Mancia G. Blood pressure variability, cardiovascular risk and antihypertensive treatment. J Hypertens Suppl 1995;4:S27-34.
48 Ravogli A, Arzilli F, OMBONI S, Giovannetti R, Mutti E, Salvetti A, Mancia G. Lack of effect of percutaneous transluminal renal angioplasty on nocturnal hypotension in renovascular hypertensive patients. J Hypertens 1996;1:53-6.
49 Parati G, Frattola A, OMBONI S, Mancia G, Di Rienzo M. Analysis of heart rate and blood pressure variability in the assessment of autonomic regulation in arterial hypertension. Clin Sci (Lond) 1996;91 Suppl:129-32.
50 Mancia G, Parati G, OMBONI S, Ravogli A, Villani A, Santucciu C, Ulian L. Ambulatory blood pressure monitoring in the ELSA study. European Lacidipine Study on Atherosclerosis. Blood Press Suppl 1996;4:36-8.
51 Mancia G, OMBONI S. Ambulatory blood pressure, blood pressure variability and antihypertensive treatment. Clin Exp Hypertens. 1996;3-4:449-62.
52 Mancia G, OMBONI S, Parati G. Lessons to be learned from 24-hour ambulatory blood pressure monitoring. Kidney Int Suppl 1996;55:S63-8.
53 Parati G, OMBONI S, Mancia G. Difference between office and ambulatory blood pressure and response to antihypertensive treatment. J Hypertens. 1996;6:791-7.
54 OMBONI S, Parati G, Di Rienzo M, Wieling W, Mancia G. Blood pressure and heart rate variability in autonomic disorders:a critical review. Clin Auton Res 1996;3:171-82.
55 Mancia G, Gamba PL, OMBONI S, Paleari F, Parati G, Sega R, Zanchetti A. Ambulatory blood pressure monitoring. J Hypertens Suppl 1996;2:S61-6;discussion S66-8.
56 OMBONI S, Parati G, Groppelli A, Ulian L, Mancia G. Performance of the AM-5600 blood pressure monitor:comparison with ambulatory intra-arterial pressure. J Appl Physiol 1997;2:698-703.
57 Mancia G, OMBONI S, Parati G. Assessment of antihypertensive treatment by ambulatory blood pressure. J Hypertens Suppl 1997;2:S43-50.
58 Mancia G, OMBONI S, Grassi G. Combination treatment in hypertension:the VeraTran Study. Am J Hypertens 1997;7 Pt 2:153S-158S.
59 Zanchetti A, OMBONI S, Di Biagio C. Candesartan cilexetil and enalapril are of equivalent efficacy in patients with mild to moderate hypertension. J Hum Hypertens 1997;2:S57-9.
60 Baccelli G, Reggiani P, Mattioli A, Corbellini E, Garducci S, Catalano M, OMBONI S. Hemodynamic changes in the lower limbs during treadmill walking in normal subjects and in patients with arteriosclerosis obliterans. Angiology 1997;9:795-803.
61 Santucciu C, Parati G, Ulian L, OMBONI S, Mancia G. [The difference between clinical ambulatory measured blood pressure and daily monitored pressure does not reflect the "white coat effect"]. Cardiologia 1997;10:1067-9.
62 Parati G, OMBONI S, Staessen J, Thijs L, Fagard R, Ulian L, Mancia G. Limitations of the difference between clinic and daytime blood pressure as a surrogate measure of the 'white-coat' effect. Syst-Eur investigators. J Hypertens 1998;1:23-9.
63 Mancia G, OMBONI S, Zanchetti A. Clinical advantages of lipophilic dihydropyridines. Blood Press Suppl. 1998;2:23-6.
64 Parati G, Ulian L, Santucciu C, OMBONI S, Mancia G. Difference between clinic and daytime blood pressure is not a measure of the white coat effect. Hypertension 1998;5:1185-9.
65 OMBONI S, Parati G, Palatini P, Vanasia A, Muiesan ML, Cuspidi C, Mancia G. Reproducibility and clinical value of nocturnal hypotension:prospective evidence from the SAMPLE study. Study on Ambulatory Monitoring of Pressure and Lisinopril Evaluation. J Hypertens 1998;6:733-8.

OMBONI S, Parati G, Mancia G. The trough:peak ratio and the smoothness index in the evaluation of control of 24 h blood pressure by treatment in hypertension. Blood Press Monit 1998;3:201-204.
67 OMBONI S, Parati G, Castiglioni P, Di Rienzo M, Imholz BP, Langewouters GJ, Wesseling KH, Mancia G. Estimation of blood pressure variability from 24-hour ambulatory finger blood pressure. Hypertension 1998;1:52-8.
68 OMBONI S, Fogari R, Palatini P, Rappelli A, Mancia G. Reproducibility and clinical value of the trough-to-peak ratio of the antihypertensive effect:evidence from the sample study. Hypertension 1998;3:424-9.
69 Mancia G, Cattaneo BM, OMBONI S, Grassi G. Clinical benefits of a consistent reduction in blood pressure. J Hypertens Suppl 1998;6:S35-9.
70 Parati G, OMBONI S, Rizzoni D, Agabiti-Rosei E, Mancia G. The smoothness index:a new, reproducible and clinically relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension. J Hypertens 1998;11:1685-91.
71 OMBONI S, Zanchetti A. Antihypertensive efficacy of lercanidipine at 2.5, 5 and 10 mg in mild to moderate essential hypertensives assessed by clinic and ambulatory blood pressure measurements. Multicenter Study Investigators. J Hypertens 1998;12 Pt 1:1831-8.
72 Mancia G, Parati G, OMBONI S, Ulian L, Zanchetti A. Ambulatory blood pressure monitoring. Clin Exp Hypertens 1999;5-6:703-15.
73 Castiglioni P, Parati G, OMBONI S, Mancia G, Imholz BP, Wesseling KH, Di Rienzo M. Broad-band spectral analysis of 24 h continuous finger blood pressure:comparison with intra-arterial recordings. Clin Sci (Lond) 1999;2:129-39.
74 OMBONI S, Parati G, Mancia G. [Monitoring of blood pressure for 24 hours:historical, technical, and methodological features]. Cardiologia 1999;1(Pt 2):997-1000.
75 Parati G, OMBONI S, Mancia G. [Trough-peak ratio and the smoothness index in the assessment of duration and homogeneity of 24-hour antihypertensive effect]. Cardiologia 1999;1(Pt 1):345-8.
76 Mancia G, OMBONI S, Parati G. The importance of blood pressure variability in hypertension. Blood Press Monit 2000;1:S9-S15.
77 Mancia G, OMBONI S, Agabiti-Rosei E, Casati R, Fogari R, Leonetti G, Montemurro G, Nami R, Pessina AC, Pirrelli A, Zanchetti A. Antihypertensive efficacy of manidipine and enalapril in hypertensive diabetic patients. J Cardiovasc Pharmacol 2000;6:926-31.
78 OMBONI S, Fogari R, Mancia G. A smooth blood pressure control is obtained over 24 h by delapril in mild to moderate essential hypertensives. Blood Press 2001;3:170-5.
79 Zanchetti A, OMBONI S. Comparison of candesartan versus enalapril in essential hypertension. Italian Candesartan Study Group. Am J Hypertens 2001;2:129-34.
80 Parati G, OMBONI S, Villani A, Glavina F, Castiglioni P, Di Rienzo M, Mancia G. Reproducibility of beat-by-beat blood pressure and heart rate variability. Blood Press Monit 2001;4:217-20.
81 Mancia G, OMBONI S, Parati G, Clement DL, Haley WE, Rahman SN, Hoogma RP. Twenty-four hour ambulatory blood pressure in the Hypertension Optimal Treatment (HOT) study. J Hypertens 2001;10:1755-63.
82 Zanchetti A, OMBONI S, La Commare P, De Cesaris R, Palatini P. Efficacy, tolerability, and impact on quality of life of long-term treatment with manidipine or amlodipine in patients with essential hypertension. J Cardiovasc Pharmacol 2001;4:642-50.
83 Mancia G, Parati G, Hennig M, Flatau B, OMBONI S, Glavina F, Costa B, Scherz R, Bond G, Zanchetti A;ELSA Investigators. Relation between blood pressure variability and carotid artery damage in hypertension:baseline data from the European Lacidipine Study on Atherosclerosis (ELSA). J Hypertens 2001;11:1981-9.
84 OMBONI S, Smit AA, van Lieshout JJ, Settels JJ, Langewouters GJ, Wieling W. Mechanisms underlying the impairment in orthostatic tolerance after nocturnal recumbency in patients with autonomic failure. Clin Sci (Lond) 2001;6:609-18.
85 Antonicelli R, OMBONI S, Giovanni DC, Ansuini R, Mori A, Gesuita R, Parati G, Paciaroni E. Smooth blood pressure control obtained with extended-release felodipine in elderly patients with hypertension: evaluation by 24-hour ambulatory blood pressure monitoring. Drugs Aging 2002;7:541-51.
86 Porcellati C, OMBONI S. Switching from ACE inhibitors, beta-blockers, calcium antagonists or diuretics to candesartan improves efficacy and tolerability. Blood Press 2002;5:310-9.
87 Mancia G, OMBONI S, Parati G;Investigators of the INSIGHT ABPM substudy. Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT). J Hypertens 2002;3:545-53.
88 Taddei S, OMBONI S, Ghiadoni L, Caiazza A, Fogari R, Innocenti P, Porcellati C, Giovannetti R, Corradi L, Mancia G, Salvetti A. Combination of lisinopril and nifedipine GITS increases blood pressure control compared with single drugs in essential hypertensive patients. J Cardiovasc Pharmacol 2003;4:579-85.
89 Mancia G, OMBONI S;CARDIO (CAndesaRtan combined with DIuretic in hypertensiOn) Study Group. Candesartan plus hydrochlorothiazide fixed combination vs previous monotherapy plus diuretic in poorly controlled essential hypertensive patients. Blood Press Suppl 2004;2:11-7.
90 Malacco E, Piazza S, OMBONI S;on behalf of the Zofenopril Study Group. Zofenopril versus Lisinopril in the Treatment of Essential Hypertension in Elderly Patients: A Randomised, Double-Blind, Multicentre Study. Clin Drug Investig 2005;3:175-182.
91 Mancia G, Parati G, Bilo G, Maronati A, OMBONI S, Baurecht H, Hennig M, Zanchetti A. Assessment of long-term antihypertensive treatment by clinic and ambulatory blood pressure:data from the European Lacidipine Study on Atherosclerosis. J Hypertens 2007;5:1087-94.
92 Orzalesi N, Rossetti L, OMBONI S;OPTIME Study Group (Osservatorio sulla Patologia glaucomatosa, Indagine Medico Epidemiologica);CONPROSO (Collegio Nazionale dei Professori Ordinari di Scienze Oftalmologiche). Vascular risk factors in glaucoma:the results of a national survey. Graefes Arch Clin Exp Ophthalmol 2007;6:795-802.
93 Pini C, Pastori M, Baccheschi J, OMBONI S, Parati G;European Society of Hypertension. Validation of the Artsana CSI 610 automated blood pressure monitor in adults according to the International Protocol of the European Society of Hypertension. Blood Press Monit 2007;3:179-84.
94 Bussone G, Tullo V, d'Onofrio F, Petretta V, Curone M, Frediani F, Tonini C, OMBONI S. Frovatriptan for the prevention of postdural puncture headache. Cephalalgia 2007;7:809-13.
95 OMBONI S, Riva I, Giglio A, Caldara G, Groppelli A, Parati G. Validation of the Omron M5-I, R5-I and HEM-907 automated blood pressure monitors in elderly individuals according to the International Protocol of the European Society of Hypertension. Blood Press Monit 2007;4:233-42.

96. Malacco E, OMBONI S. Antihypertensive efficacy of zofenopril plus hydrochlorothiazide fixed combination for treatment in metabolic syndrome. Adv Ther 2007;5:1006-15.
97 Pecori Giraldi F, Toja PM, De Martin M, Maronati A, Scacchi M, OMBONI S,Cavagnini F, Parati G. Circadian blood pressure profile in patients with active Cushing's disease and after long-term cure. Horm Metab Res 2007;12:908-14.
98 Pini C, Natalizi A, Gerosa PF, Frigerio M, OMBONI S, Parati G. Validation of the Artsana CS 410 automated blood pressure monitor in adults according to the International Protocol of the European Society of Hypertension. Blood Press Monit 2008;13:177-182.
99 OMBONI S, Costantini C, Pini C, Bulegato R, Manfellotto D, Rizzoni D, Palatini P, O'brien E, Parati G. PA.NET International Quality Certification Protocol for blood pressure monitors. Blood Press Monit 2008;13:285-289.
100 Parati G, OMBONI S, Palatini P, Rizzoni D, Bilo G, Valentini M, Agabiti-Rosei E, Mancia G. Italian Society of Hypertension Guidelines for Conventional and Automated Blood Pressure Measurement in the Office, at Home and Over 24 Hours. High Blood Pressure & Cardiovascular Prevention 2008;15:283-310.

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Research Interest: Rehabilitation, Working with Older People, Diabetes, Stroke Care, Research 

Dr. Gorelik has nearly 35 years of experience in clinical medicine and research. He has published more than 60 scientific publications. Currently, Dr. Gorelik serves as the Head of the Department of Internal Medicine "F" in the Assaf Harofeh Medical Center, Zerifin, Israel. He is also a Clinical Senior Lecturer in the Sackler Faculty of Medicine of the Tel Aviv University.

Research Interest: Diabetes, Orthostatic Hypotension, Magnesium Metabolism, Heart Failure and Hospital Internal Medicine.

Number of Publications: 57

Research Interest: Epidemiology of Diabetes; Mechanism of Insulin Action; Insulin Resistance; Obesity and Insulin Resistance; Cardiovascular Risk Diabetes and Obesity; Bone Metabolism and Diabetes and Obesity; Gene Adiposities Tissue in Diabetes and Obesity. 

Research Interest: Diabetes; Metabolic Syndrome; Osteoporosis

Research Interest: Deep Specialization in Research Involve; Obesity and Associated Disorder, Its Mechanism and Treatment. Metabolic Syndrome-Food Additives and Its Effect on the Bodyorgans. Also the Biochemical, Oxidative Stress and Advanced Biomarkers in Health and Diseases. Recently Involved in Nanomedical Materials as Antioxidant for Health Maintainance.

Research Interest: Integrated Pharmaco-Physiology, Brain-Gut Interactions, Stress-Related Functional Gastrointestinal Diseases, Ingestive Behavior-Associated Gastrointestinal Neuroendocrinology, and Bariatric Surgery

Research Interest: Liver Cirrhosis, Gastrointestinal Diseases, Liver, Hepatitis, Chronic Hepatitis C, Cirrhosis, Bacteria, Virulence Factors, Cells

Research Interest: Evaluation of biological activity of plant foods: anti-inflammatory, anti-glycation, anti-oxidant activities Influences of heat treatment on biological activity of foods.

List of Publications:

1.    Ho, Su-Chen, Chang, Yi-Huang, “Comparison of inhibitory capacities of 6-, 8- and 10-gingerols/shogaols on the canonical NLRP3 inflammasome-mediated IL-1β secretion” Molecules, Vol. 23, 2018, 02, p. 466.
2.    Ho, Su-Chen, Su, Min-Sheng, Lin, Chih- Cheng, Chiu, Chui-Feng, “Comparison of anti-glycation capacity of two new purple-colored-leaf tea cultivars with an ordinary green-colored-leaf tea cultivar in Taiwan,” Global Journal of Obesity, Diabetes and Metabolic Syndrome, Vol. 4, No. 1, 2017, 02, pp. 009-015.
3.    Yang, Tzu-Ting, Ho, Su-Chen, Chuang, Lu-Te, Chuang, Hsiao-Chi, Li, Ya-Ting, Wu, Jyun-Jie, “Characterization of particulate-phase polycyclic aromatic hydrocarbons emitted from incense burning and their bioreactivity in RAW264.7 macrophage,” Environmental Pollution, Vol. 220, 2017, 01, pp. 1190-1198.
4.    Ho, Su-Chen, Su, Min-Sheng, “Optimized heat treatment enhances the anti-inflammatory capacity of ginger “ International Journal of Food Properties, Vol. 19, 2016, pp. 1884-1898.
5.    Ho, Su-Chen, Su, Min-Sheng, “Evaluating the anti-neuroinflammatory capacity of raw and steamed garlic as well as five organosulfur compounds,” Molecules, Vol. 19, No. 11, 2014, pp. 17697-17714.
6.    Ho, Su-Chen, Kuo, Chun-Ting, “Hesperidin, Nobiletin, and Tangeretin Are Collectively Responsible for the Anti-neuroinflammatory Capacity of Tangerine Peel (Citri reticulatae pericarpium)” Food and Chemical Toxicology, Vol. 71, 2014, pp. 176-182.
7.    Ho, Su-Chen, Chang, Pei-Wen, Tong, Hui-Ting, Yu, Pin-Yuan, “Inhibition of Fluorescent Advanced Glycation End-products and N-carboxymethyllysine Formation by Several Floral Herbal Infusions,” International Journal of Food Properties, Vol. 17, 2014, pp. 617-628.
8.    Ho, Su-Chen, Su, Min-Sheng, Lin, Chih-Cheng, “Comparison of Peroxynitrite-Scavenging Capacities of Several Citrus Fruit Peels,” International Journal of Food Properties, Vol. 17, 2014, pp. 111-124.
9.    Ho, Su-Chen, Chang, Ku-Shang, Lin, Chih-Cheng, “Anti-neuroinflammatory Capacity of Fresh Ginger Is Attributed Mainly to 10-Gingerol,” Food Chemistry, Vol. 141, No. 3, 2013, 12, pp. 3183-3191.
10.    Ho, Su-Chen, Chang, Ku-Shang, Chang, Pei-Wen, “Inhibition of Neuroinflammation by Cinnamon and its Main Components,” Food Chemistry, Vol. 138, No. 4, 2013, pp. 2275-2282.
11.    Ho, Su-Chen, Chang, Pei-Wen, “Inhibitory Effects of Several Spices on Inflammation Caused by Advanced Glycation Endproducts,” American Journal of Plant Sciences, Vol. 3, No. 7, 2012, pp. 995-1002.
12.    Ho, Su-Chen, Wu, Szu-Pei, Lin, Shyh-Mirn, Tang, Ya-Li, “Comparison of Anti-glycation Capacities of Several Herbal Infusions with that of Green Tea,” Food Chemistry, Vol. 122, 2010, pp. 768-744.
13.    Lin, Shih-Min, Wang, Shih-Wei, Ho, Su-Chen, Tang, Ya-Li, “Protective Effect of Green Tea (-)-Epigallocatechin-3-gallate (EGCG) Against the Monoamine Oxidase B Enzyme Activity Increase in Adult Rat Brains,” Nutrition, Vol. 26, 2010, pp. 1195-1200.
14.    Huang, Yung-Sheng, Ho, Su-Chen, “Polymethoxy Flavones Are Responsible for the Anti-inflammatory Activity of Citrus Fruit Peel,”Food Chemistry, Vol. 119, 2010, pp. 868-873.
15.    Ho, Su-Chen, Tang, Ya-Li, Lin, Shih-Min, Liew, Yih-Fong, “Evaluation of Peroxynitrite-Scavenging Capacities of Several Commonly Used Fresh Spices,” Food Chemistry, Vol. 119, 2010, pp. 1102-1107.
16.    Ho, Su-Chen, Lin, Chih-Cheng, “Investigation of Heat Treating Conditions for Enhancing the Anti-inflammatory Activity of Citrus Fruit (Citrus reticulata) Peels,”Journal of Agricultural and Food Chemistry, Vol. 56, 2008, pp. 7976-7982.
17.    Lin, Chih-Cheng, Hung, Pi-Fong, Ho, Su-Chen, “Heat Treatment Enhances the NO-suppressing and Peroxynitrite-intercepting Activities of Kumquat’s (Fortunella margarita Swingle) Peel,”Food Chemistry, Vol. 109, 2008, pp. 95-103.
18.    Ho, Su-Chen, Tsai, Tzung-Hsun, Tsai, Po-Jung, Lin, Chih-Cheng, “Protective Capacities of Certain Spices Against Peroxynitrite-mediated Biomolecular Damage,”Food and Chemical Toxicology, Vol. 46, 2008, pp. 920-928.
19.    Ho, Su-Chen, Hwang, Lucy Sun, Shen, Yi-Jane, Lin, Chih-Cheng, “Suppressive Effect of a Proanthocyanidin-rich Extract from Longan (Dimocarpus longan Lour.) Flowers on Nitric Oxide Production in LPS-Stimulated Macrophage Cells,”Journal of Agricultural and Food Chemistry, Vol. 55, No. 26, 2007, pp. 10664-10670.
20.    Tsai, Po-Jung, Tsai, Tzung-Hsun, Ho, Su-Chen, “In vitro Inhibitory Effects of Rosemary Extracts on Growth and Glucosyltransferase Activity of Streptococcus sobrinus,” Food Chemistry, Vol. 105, 2007, pp. 311-316.
21.    Tsai, Po-Jung, Tsai, Tzung-Hsun, Yu, Chun-Hsien, Ho, Su-Chen, “Evaluation of NO-suppressing Activity of Several Mediterranean Culinary Spices,” Food and Chemical Toxicology, Vol. 45, 2007, pp. 440-447.
22.    Tsai, Po-Jung, Tsai, Tzung-Hsun, Yu, Chun-Hsien, Ho, Su-Chen, “Comparison of NO-scavenging and NO-suppressing Activities of Different Herbal Teas with those of Green Tea,” Food Chemistry, Vol. 103, 2007, pp. 181-187.
23.    Lin, Chih-Cheng, Lu, Min-Jer, Chen, Shen-Jen, Ho, Su-Chen, “Heavy Fermentation Impacts NO-Suppressing Activity of Tea in LPS-activated RAW 264.7 Macrophages,” Food Chemistry, Vol. 98, 2006, pp. 483-489.
24.    Tsai, Tzung-Hsun, Tsai, Po-Jung, Ho, Su-Chen, “Antioxidant and Antiinflammatory Activities of Several Commonly Used Spices,” Journal of Food Science, Vol. 70, No. 1, 2005, pp. pp. C93-C97.
25.    Tsai, Po-Jung, Yu, Chun-Hsien, Hsu SP, Lee YH, Huang IT, Ho, Su-Chen, Chu CH “Maternal plasma adiponectin concentrations at 24 to 31 weeks of gestation: Negative association with gestational diabetes mellitus” Nutrition, Vol. 21, No. 11-12, 2005, pp.1095-9 •
26.    Tsai, Po-Jung, Ho, Su-Chen, Tsai LP, Lee YH, Hsu SP, Yang SP, Chu CH, Yu, Chun-Hsien, “Lack of relationship between beta3-adrenergic receptor gene polymorphism and gestational diabetes mellitus in a Taiwanese population” Metabolism, Vol. 53, No. 9, 2004, pp.1136-9.
27.    Tsai, Po-Jung, Yu, Chun-Hsien, Hsu SP, Lee YH, Chiou CH, Hsu YW, Ho, Su-Chen, Chu CH. “Cord plasma concentrations of adiponectin and leptin in healthy term neonates: positive correlation with birthweight and neonatal adiposity” Clin. Endocrinol. Vol. 61, 2004, pp. 88-93.
28.    Ho, Su-Chen, Tsai, Po-Jung, ”Comparison of the effects of "hot" and "cold" Chinese medicinal plants on the production of inflammatory mediators by RAW 264.7 cells” Journal of Food and Drug Analysis, Vol. 12, No. 2, 2004, pp. 120-127.

Lawrence Lavery is a Professor in the Department of Plastic Surgery, as well as Director of Clinical Research in the Department of Plastic Surgery, at the University of Texas Southwestern Medical Center, Dallas, TX.  His research group has published 210 peer reviewed papers and has received extramural funding from the Veterans Administration, the National Institute of Health, the Agency for Healthcare Research and Quality, the American Diabetes Association, and the American College of Foot and Ankle Surgeons. 

Research Interest: Diabetes, Ulcers, Infections, Neuropathy and Osteomyelities

Grants: Supporting with number of grants

List of Publications:
1.    Lavery LA, Oz OK, Bhavan K, Wukich DK.  Diabetic Foot Syndrom in the Twenty-First Century.  Clin Podiatr Med Surg. 2019 July; 3, 355-359.
2.    Kim, PJ, Attinger CE, Orgill D, Galiano RD, Steinberg JS, Evans KK, Lavery LA.  Complex Lower Extremity Wound in the Complex Host:  Results from a Multicenter Registry.  Plastic and Reconstructive Surgery-Global. 2019 Apr.  Epub ahead of print.
3.    Ahn J, Raspovic KM, Liu GT, Lavery LA, La Fontaine J, Nakonezny PA, Wukich, DK.  Lower Extremity Necrotizing Fasciitis in Diabetic and Nondiabetic Patients:  Mortality and Amputation.  Int J Low Extrem Wounds.  2019 Apr.  Epub ahead of print.  PMID: 30929530.
4.    Lavery LA, Bhavan K, Wukich DK.  Biofilm and diabetic foot ulcer healing:  all hat and no cattle.  Annals of Translational Medicine 2019 Mar.  Epub ahead of print.
5.    La Fontaine J, Crisologo PA, Lavery L.  Current concepts in curative surgery for diabetic forefoot ulcers.  The Foot 2019 Jan 10 (39) 37-44.  Epub ahead of print.
6.    Olson E, Mahar KM, Morgan L, Fillmore C, Holland C, Lavery L.  Randomized Phase I Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Topical Daprodustat in Healthy Volunteers and Patients with Diabetic Foot Ulcers.  Clin Pharmacol Drug Dev. 2019 Feb 5. Epub ahead of print.  PMID:  30720931.
7.    Liu JW, Ahn J, Raspovic KM, Liu GT, Nakonezny PA, Lavery LA, Wukich DK.  Increased Rates of Readmission, Reoperation, and Mortality Following Open Reduction and Internal Fixation of Ankle Fractures are Associated with Diabetes Mellitus. J Foot Ankle Surg. 2019 Feb 11. Epub ahead of print.
8.    Ryan EC, Ahn J, Wukich DK, Kim PJ, La Fontaine J, Lavery LA.  Diagnostic Utility of Erythrocyte Sedimentation Rate and C-Reactive Protein in Osteomyelitis of the Foot in Persons without Diabetes.  J Foot Ankle Surg. 2019 Jan 23.  Epub ahead of print.
9.    Ahn J, Raspovic KM, Liu GT, Lavery LA, La Fontaine J, Nakonezny PA, Wukich DK.  Rental Function as a Predictor of Early Transmetatarsal Amputation Failure.  Foot Ankle Spec. 2018 Dec 12.  Epub ahead of print.  PMID:  30537872.
10.    Lavery LA, Crisologo PA.  Non-invasive vascular screening test to diagnose peripheral vascular disease.  Ann Transl Med. 2018 Dec; 6(Suppl 2).  PMID:  30740429.
11.    Yavuz M, Ersen A, Hartos J, LAVERY LA, Wukich D, Hirschman G, Armstrong D, Quiben M, Adams L.  Temperature as a Causative factor in Diabetic Foot Ulceration:  A Call to Revisit Ulcer Pathomechanics.  J Am Podiatr Med Assoc. 2018 Nov 14. (Epub ahead of print).  PMID:  30427732.
12.    Niederauer MQ, Michalek JE, Liu Q, Papas KK, LAVERY LA, Armstrong DG.  Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control:  a randomized, double-blind, multicenter study.  J Wound Care.  2018 Sep 1;27(Sup9): S30-S45. PMID: 30207844.
13.    LAVERY, LA, Fulmer J, Shebetka KAS, Regulski M, Vayer, D, Fried D, Kashefsky H, Owings TM, Nadarajah J, Phelan DHK.  Open-label Extension Phase of a Chronic Diabetic Foot Ulcer Multicenter, Controlled, Ramdomised Clinical Trial Using Cryopreserved Placental Membrance.  Wounds Epub 2018 June.  PMID:  30256747.
14.    Raspovic KM, Wukich DK, Naiman DQ, LAVERY LA, Kirsner RS, Kim PJ, Steinberg JS, Attinger CE, Danilkovitch A.  Effectiveness of viable cryopreserved placental membranes for management of diabetic foot ulcers in a real world setting.  Wound Repair Regen, 2018 Mar; 26(2): 213-220.  PMID:  29683538.
15.    Ahn J, Del Core MA, Wukich DK, Liu GT, Lalli T, VanPelt MD, La Fontaine J, Lavery LA, Raspovic KM.  Scoring mental health quality of life with the SF-36 in patients with and without diabetes foot complications.  Int J Low Extrem Wounds.  2018 Mar.  PMID:  29546783.
16.    LAVERY LA, Lavery DC, Hunt NA, La Fontaine J, Lavery RD.  Does the start of dialysis initiate a period of increased risk of ulceration or amputation?  J Am Podiatr Med Assoc.  2018 Jan; 108-(1):1-5.  PMID:  29547031.
17.    Van Asten SAV, Mithani M, Peters EIG, La Fontaine J, Kim PJ, Lavery LA.  Complications during the treatment of diabetic foot osteomyelitis.  Diabetes Res Clin Pract. 2018 Jan;135:58-64. PMID: 28951333. 
18.    Crisologo PA, Lavery LA.  Remote home monitoring to identify and prevent diabetic foot ulceration.  Ann Transi Med.  2017 Nov;5(21):430.  PMID:  29201882.
19.    Lavery LA, Ryan EC.  Does Continuous Diffusion of Oxygen Improve Diabetic Foot Ulcer Healing?  J Diabetes Sci Technol. 2017 Sep; 11(5):892-893.  PMID: 28728437.
20.    Sanniec K, Nguyen T, van Asten S, La Fontaine J, Lavery LA.  Split-Thickness Skin Grafts to the Foot and Ankle of Diabetic Patients.  J Am Podiatr Med Assoc.  2017 Sep; 107(5):365-368.  PMID:  29077498.

Principal Investigator (PU) – UMR Inserm UMR-S1172

"Alzheimer & Tauopathies" Jean-Pierre Aubert Research Centre, 1 Place de Verdun, Lille, France, didier.vieau@inserm.fr, didier.vieau@univ-lille.fr

Professional experience  

1986-1990: PhD in Endocrinology. Pierre et Marie Curie University of Paris (Paris VI), France. Laboratory of Endocrinology, Cochin Hospital. Thesis supervisor (Pr X. Bertagna). Thesis title: “Proopiomelanocortin and neuroendocrine differentiation markers in human tumoral pathology”

1991-1995: Laboratory of Biochemical Endocrinology (Dr. NG Seidah), Clinical Research Institute of Montreal, Montreal, Canada.

1996-1999: European Institute for Peptide Research (IFRMP 23), Laboratory of Cellular and Molecular Neuroendocrinology (Dr H Vaudry), University of Rouen, 76821 Mont-Saint-Aignan, France.

1999-2002: associate professor in the Laboratory of Endocrinology of Annelids (University of Lille 1, France, Pr M Salzet).

2002-2012: Professor of University (Animal Physiology) and head of the laboratory of maternal perinatal undernutrition (EA4489), University of Lille 1, France.

2012-2016: Dean of the department of Biology of the University Lille 1

September 2016-: Member of UMR Inserm UMR-S1172 "Alzheimer & Tauopathies" (Dr L Buée)

June 2019: Vice-President of the ‘Société des Sciences, des Arts et de l’Agriculture de Lille (SAAL)”

Research Interest: perinatal programming of metabolic disease, neuroendocrinology, Alzheimer disease, adaptation to stress.

Skype ID:  didier vieau (didiervieau@hotmail.com)

List of Publications:

Original papers

Ao 1. Vieau D, Massias JF, Girard F, Luton JP and Bertagna X. 1989. Corticotrophin like-intermediary lobe peptide as a marker of alternate proopiomelanocortin processing in ACTH producing non-pituitary tumors. Clin. Endocrinol.; 31 : 691-700.
Ao 2. Lalau JD, Vieau D, Tenenbaum F, Westeel PF, Mesmacque A, Lenne F and Quichaud J. 1990. A case of pseudo-Nelson’s syndrome : cure of ACTH hypersecretion by removal of a bronchial carcinoid tumor responsible for Cushing’s syndrome. J. Endocrinol. Invest.; 13 : 531-537.
Ao 3. de Keyzer Y, Lenne F, Massias JF, Vieau D, Luton JP, Kahn A and Bertagna X. 1990. Pituitary like proopiomelanocortin transcripts in human leydig cell tumors. J. Clin. Invest.; 86 : 871-877.
Ao 4. Massias JF, Hardouin S, Vieau D, Lenne F and Bertagna X. 1994. Phosphorylated forms of ACTH and CLIP in human tumors. Eur. J. Endocrinol.;  131 : 341-346.

Ao 5. Vieau D, Tougard C, Rosenbaum E, Lenne F and Bertagna X. 1991. The secretory granule peptide 7B2 is secreted in parallel with proopiomelanocortin and its end products by the mouse corticotrope cells At-T20. J. Neuroendocrinol.; 3 : 229-231.
Ao 6. Vieau D, Rojas-Miranda A, Verley JM, Lenne F and Bertagna X. 1991. The secretory granule peptides 7B2 and CCB are sensitive biochemicals markers of neuroendocrine bronchial tumors in man. Clin. Endocrinol.; 35 : 319-325.
Ao 7. Texier PL, de Keyzer Y, Lacave R, Vieau D, Lenne F, Rojas-Miranda A, Verley F, Luton JP, Kahn A and Bertagna X. 1991. Proopiomelanocortin gene expression in normal and tumoral human lung. J. Clin. Endocrinol. Metab.; 73 : 414-420.
Ao 8. Vieau D, Linard C, M’Bikay M, Lenne F, Chrétien M, Luton JP and Bertagna X. 1992. Expression of the neuroendocrine cell marker 7B2 in human ACTH secreting tumours. Clin. Endocrinol.; 36 : 597-603.
Ao 9. Lusson J, Vieau D, Hamelin J, Day R, Chrétien M and Seidah NG. 1993. cDNA structure of the mouse and rat subtilisin/kexin-like PC5 : a candidate proprotein convertase expressed in endocrine and nonendocrine cells. Proc. Natl. Acad. Sci. USA; 90 : 6691-6695.
Ao 10. Dong W, Marcinkiewicz M, Vieau D, Chrétien M, Seidah NG and Day R. 1995. Distinct mRNA expression of the highly homologous convertases PC5 and PACE4 in the rat brain and pituitary. J. Neuroscience; 15 : 1778-1796.
Ao 11. Vieau D, Seidah NG and Day R. 1995. Characterization of prodynorphin derived products in the mouse pancreatic tumoral cell line TC3 : a unique model for the study of prodynorphin processing. Endocrinology; 136 : 1187-1196.
Ao 12. Vieau D, Seidah NG, M’Bikay M, Chrétien M and Bertagna X. 1994. Expression of the prohormone convertase PC2 correlates with the presence of CLIP in human ACTH secreting tumors. J. Clin. Endocrinol. Metab.; 75 : 1503-1506. 
Ao 13. Tostivint H, Lihrmann I, Bucharles C, Vieau D, Coulouarn Y, Fournier A, Conlon JM and Vaudry H. 1996. Occurrence of two somatostatin variants in the frog brain : characterization of the cDNAs, distribution of the mRNAs and receptor-binding affinities of the peptides. Proc. Natl. Acad. Sci. USA; 93 : 12605-12610.
Ao 14. Vieau D, Gangnon F, Jégou S, Danger JM and Vaudry H. 1998. Characterization of the cDNA encoding the prohormone convertase PC2 and localization of the mRNA in the brain of the frog Rana ridibunda. Mol. Brain. Res.; 63 : 1-13.
Ao 15. Gangnon F, Danger JM, Jégou S, Vieau D, Seidah NG and Vaudry H. 1999. Molecular cloning, characterization of the cDNA, and distribution of mRNA encoding the frog prohormone convertase PC1. J. Comp. Neurol.; 405 : 160-172.
Ao 16. Tostivint H, Vieau D, Chartrel N, Boutelet I, Galas L, Fournier A, Lihrmann I and Vaudry H. 2002. Expression and processing of the Pro2,Met13Somatostatin-14 precursor in the intermediate lobe of the frog pituitary. Endocrinology ; 143 : 3472-3481. 1er auteur ex æquo.

Ao 17. Sebaai N, Lesage J, Vieau D, Alaoui A, Dupouy JP, Deloof S. 2002. Altered control of the hypothalamo-pituitary-adrenal axis in adult male rats exposed perinatally to food deprivation and/or dehydration. Neuroendocrinology ; 76 : 243-253.
Ao 18. Gangnon F, Jegou S, Vallarino M, Vieau D and Vaudry H. 2003. Molecular characterization of the cDNA and localization of the mRNA encoding the Prohormone Convertase PC5-A in the European Green Frog. J. Comp. Neurol. ;456 : 60-72.

Ao 19. Matias I, Leonhardt M, Lesage J, De  Petrocellis L, Dupouy JP, Vieau D, Di Marzo V. 2003. Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels. Cell Mol Life Sci. ; 60 : 382-389.

Ao 20. Deloffre L, Salzet B, Vieau D, Andries JC, Salzet M. 2003. Antibacterial properties of hemerythrin of the sand worm Nereis diversicolor. Neuro Endocrinol Lett. ; 24 : 39-45.

Ao 21. Lesage J, Del-Favero F, Leonhardt M, Louvart H, Maccari S, Vieau D, Darnaudery M. 2004. Prenatal stress induces intrauterine growth restriction and programmes glucose intolerance and feeding behaviour disturbances in the aged rat. J. Endocrinol. ; 181: 291-296. 

Ao 22. Deloffre L, Sautiere PE, Huybrechts R, Hens K, Vieau D, Salzet M. 2004. Angiotensin-converting enzyme inhibition studies by natural leech inhibitors by capillary electrophoresis and competition assay. Eur. J. Biochem. ; 271: 2101-2106.

Ao 23. Sebaai N, Lesage J, Breton C, Vieau D, Deloof S. 2004. Perinatal food deprivation induces marked alterations of the hypothalamo-pituitary-adrenal axis in 8-month-old male rats both under basal conditions and after a dehydration period. Neuroendocrinology; 79 : 163-173.

Ao 24. Riviere G, Michaud A, Deloffre L, Vandenbulcke F, Levoye A, Breton C, Corvol P, Salzet M, Vieau D. 2004. Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE. Biochem J. ; 382 : 565-573.

Ao 25. Vergote D, Sautiere PE, Vandenbulcke F, Vieau D, Mitta G, Macagno ER, Salzet M. 2004. Up-regulation of neurohemerythrin expression in the central nervous system of the medicinal leech, Hirudo medicinalis, following septic injury. J. Biol. Chem. ; 279 : 43828-43837.

Ao 26. Levoye A, Mouillac B, Riviere G, Vieau D, Salzet M, Breton C. 2005. Cloning, expression and pharmacological characterization of a vasopressin-related receptor in an annelid, the leech Theromyzon tessulatum. J. Endocrinol. ; 184 : 277-289.

Ao 27. Laborie C, Dutriez-Casteloot I, Montel V, Dickes-Coopman A, Lesage J, Vieau D. 2005. Prenatal morphine exposure affects sympathoadrenal axis activity and serotonin metabolism in adult male rats both under basal conditions and after an ether inhalation stress. Neurosci. Lett. ; 381:211-216.

Ao 28. Rivière G, Michaud A, Breton C, VanCamp G, Laborie C, Enache M, Lesage J, Deloof S, Corvol P, Vieau D. 2005. ACE2 and ACE display tissue-specific sensitivity to programmed hypertension by maternal undernutrition in the adult rat. Hypertension ; 46: 1169-1174.
Ao 29. Molendi-Coste O,  Grumolato L, Laborie C, Lesage J, Maubert E, Ghzili H, Vaudry H, Anouar Y, Breton C, Vieau D. 2006. Maternal perinatal undernutrition alters neuronal and neuroendocrine differentiation in the rat adrenal medulla at weaning. Endocrinology ; 147 : 2050-2059.
Ao 30. Salomé N, Viltart O, Lesage J, Landgraf R, Vieau D, Laborie C. 2006. Altered hypothalamo-pituitary-adrenal and sympatho-adrenomedullary activities in rats bred for high anxiety: central and peripheral correlates. Psychoneuroendocrinology ; 31 : 724-735.
Ao 31. Vallarino M, Bruzzone F, Mathieu M, Chartrel N, Vieau D, Ciarlo M, Fournier A, Vaudry H. 2006. Ontogeny of the somatostatin variant [Pro(2), Met(13)]somatostatin-14 in the brain, pituitary, and sensory organs of the frog Rana esculenta. J. Comp. Neurol. ; 497: 717-733.
Ao 32 Brulle F, Mitta G, Cocquerelle C, Vieau D, Lemiere S, Lepretre A, Vandenbulcke F. 2006. Cloning and real-time PCR testing of 14 potential biomarkers in Eisenia fetida following cadmium exposure. Environ. Sci. Technol. 40: 2844-2850.
Ao 33. Van Waes V, Enache M, Dutriez I, Lesage J, Morley-Fletcher S, Vinner E, Lhermitte M, Vieau D, Maccari S, Darnaudery M. 2006. Hypo-response of the hypothalamic-pituitary-adrenocortical axis after an ethanol challenge in prenatally stressed adolescent male rats. Eur. J. Neurosci. 2:1193-200. 
Ao 34. Mairesse  J, Lesage J, Breton C, Bréant B, Hahn T, Darnaudéry M, Dickson S, Seckl J, Vanbesien-Mailliot C, Blondeau B, Vieau D, Maccari S, Viltart O. 2007. Maternal stress alters endocrine function of the feto-placental unit in rats. Am. J. Physiol. Endocrinol. Metab. 292 :E1526-E1533.
Ao 35. Rivière G, Michaud A, Corradi HR, Cogez V, Sturrock ED, Acharya KR, Bohin JP, Vieau D, Corvol P. 2007. Characterization of the first angiotensin-converting-like enzyme in bacteria : ancestor XcACE is already active. Gene 399: 81-90.
Ao 36. Dutriez-Casteloot, Breton C, Coupé B, Hawchar O, de Keyzer Y, Deloof S, Lesage J, Vieau D. 2008. Distribution and tissue-specific programming expression of glucocorticoid receptors and 11beta-HSDs by maternal perinatal undernutrition in the adult male rat: focus on HPA axis. Horm.Metab.Res. 40: 257-261.

Ao 37. Molendi-Coste O, Mairesse J, Aubert N, H. Ghzili H, Abbadie C, Vaudry H, Gonzalez B, Anouar Y, Vieau D, Breton C, Laborie C. 2008. Maternal perinatal undernutrition impairs chromaffin cells proliferation in the postnatal rat. Horm. Metab. Res. 40 : 386-390.
Ao 38. Grumolato L, Ghzili H, Montero-Hadjadje M, Lesage J, Galas L, Ait-Ali D, Guerineau N, Elkahloun A, Fournier A, Vieau D, Vaudry H, Anouar Y. 2008. Selenoprotein T is a PACAP- and cAMP responsive gene that localizes to the ER and regulates intracellular calcium. FASEB J. 22:1756-1768.
Ao 39. Delahaye F, Breton C, Risold PY, Enache M, Dutriez-Casteloot I, Laborie C, Lesage J, Vieau D. 2008. Maternal Perinatal Undernutrition Impedes Postnatal Leptin Surge and Affects the Development of Arcuate Nucleus POMC Neurons in Neonatal Male Rat Pups. Endocrinology 149 :470-475.

Ao 40. Coupé B, Dutriez-Casteloot I, Breton C, Lefèvre F, Mairesse J, Dickes-Coopman A, Silhol M,  Tapia-Arancibia L, Lesage J, Vieau D. 2009. Maternal undernutrition modifies brain-derived neurotrophic factor expression and cell proliferation in the hippocampus and hypothalamus of the developing male rat. J. Neuroendocrinol. 21:40-48.
Ao 41. Molendi-Coste O, Laborie C, Scarpa MC, Montel V, Vieau D, Breton C. Maternal perinatal undernutrition alters postnatal development of chromaffin cells in the male rat adrenal medulla. Neuroendocrinology 90:54-66.
Ao 42. Breton C, Risold PY, Lukaszewski MA, Enache M, Guillemot J, Rivière G, Delahaye F, Lesage J, Dutriez-Casteloot I, Laborie C, Vieau D. 2009. Maternal prenatal undernutrition alters the response of POMC neurons to energy status variation in adult male rat offspring. Am. J. Physiol. Endocrinol. Metab. 296: E462-E472.
Ao 43. Delahaye F, Lukaszewski MA, Cisse O, Dutriez-Casteloot I, Montel V, Dickes-Coopman A, Laborie C, Lesage J, Breton C, Vieau D. 2010. Maternal perinatal undernutrition programs a « brown-like » phenotype of gonadal white fat in male rat at weaning. Am J Physiol Regul Integr Comp Physiol. 299: R101-R110.

Ao 44. Mayeur S, Silhol M, Moitrot E, Barbaux S, Breton C, Gabory A, Vaiman D, Dutriez-Casteloot I, Fajardy I, Vambergue A, Tapia-Arancibia L, Bastide B, Storme L, Junien C, Vieau D, Lesage J. 2010. The placental BDNF/TRKB signaling system is modulated by fetal growth in rat and human. Placenta 31: 785-791.
Ao 45 Gallou-Kabani C., Gabory A., Tost J., Karimi M., Mayeur S., Lesage J., Boudadi E., Gross M.S., Taurelle J., Vige A., Breton C., Reusens B., Remacle C., Vieau D., Ekström T., Jais J.P., Junien C. 2010. Sex- and diet-specific dysregulation of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet. PLoS One 5: e14398.
Ao 46. Rivière G, Lienhard D, Andrieu T, Vieau D, Frey BM, Frey FJ. 2011. Epigenetic regulation of somatic angiotensin-converting enzyme by DNA methylation and histone acetylation. Epigenetics 6:478-89.
Ao 47. Tanguy Y., Falluel-Morel A., Arthaud S., Boukhzar L., Manecka D.L., Chagraoui A., Prevost G., Elias S., Dorval-Coiffec I., Lesage J., Vieau D., Lihrmann I., Jégou B., Anouar Y. 2011. The PACAP-regulated gene selenoprotein T is highly induced in nervous, endocrine, and metabolic tissues during ontogenetic and regenerative processes. Endocrinology 152: 4322-35.
Ao 48. Laborie C., Molendi-Coste O., Breton C., Montel V., Vandenbulcke F., Grumolato L., Anouar Y., Vieau D. 2011. Maternal perinatal undernutrition has long-term consequences both on morphology, function and gene expression of the adrenal medulla in the adult male rat. J. Neuroendocrinol. 23: 711-24.
Ao 49. Guillemot J.*, Lukaszewski M.A.*, Montel V., Delahaye F., Mayeur S., Laborie C., Dickes-Coopman A., Dutriez-Casteloot I., Lesage J., Breton C., Vieau D. 2011. Influence of prenatal undernutrition of clozapine and aripiprazole in the adult male rat: relevance to a neurodevelopmental origin of schizophrenia. Eur. J. Pharmacol. 667: 402-9. (*co-premier auteur).
Ao 50.  Lukaszewski M.A., Mayeur S., Fajardy I., Delahaye F., Dutriez-Casteloot I., Montel V., Dickes-Coopman A., Laborie C., Lesage J., Vieau D., Breton C. 2011. Maternal prenatal undernutrition programs adipose tissue gene expression in adult male rat offspring under high-fat diet. Am. J. Physiol. Endocrinol. Metab. 301: E548-59.
Ao 51. Ivars J., Butruille L., Knauf C., Bouckenooghe T., Mayeur S., Vieau D., Valet P., Deruelle P., Lesage J. 2012. Maternal hypertension induces tissue-specific modulations of the apelinergic system in the fetoplacental unit in rat. Peptides 35: 136-8.
Ao 52. Gabory A., Ferry L. Fajardy I., Jouneau L., Gothié J.D., Vigé A., Fleur C., Mayeur S., Gallou-Kabani C., Gross M.S., Attig l., Vambergue A., Lesage J., Reusens B., Vieau D., Remacle C., Jais J.P., Junien C. 2012. Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta. PLoS One 7: e47986.
Ao 53. Mayeur S., Lancel S., Theys N., Lukaszewski M.A., Duban-Deewer S., Bastide B., Hachani J., Cecchelli R., Breton C., Gabory A., Storme L., Reusens B., Junien C., Vieau D., Lesage J. 2013. Maternal caloric restriction induces placental mitochondrial biogenesis, optimizes bioenergetic efficiency but alterates ATP production: putative involvement of mitochondria in feto-placental growth defects. Am. J. Physiol. Endocrinol. Metab. 304: E14-22.
    Ao 54. Lukaszewski M.A., Butruille L., Moitrot E., Montel V., Dickes-Coopman A., Lesage J., Laborie C., Vieau D., Breton C. 2013. The hypothalamic POMC gene expression exhibits long-term programming in prenatally undernourished male rat offspring under high-fat diet. Peptides 43: 146-54.
    Ao 55. Cisse O., Fajardy I., Dickes-Coopman A., Moitrot E., Montel V., Deloof S., Rousseaux J., Vieau D., Laborie C. 2013. Mild gestational hyperglycemia in rat induces fetal overgrowth and modulates placental growth factors and nutrient transporters expression. PLoS One 8: e64251.
Ao 56. Mayeur S., Cisse O., Gabory A., Barbaux S., Vaiman D., Vambergue A., Fajardy I., Deloof S., Junien C., Laborie C., Vieau D., Lesage J. 2013. Placental expression of the obesity-associated gene FTO is reduced by fetal growth restriction but not by macrosomia in rat and human. J. Dev. Orig. Health Dis. 4: 134-138.
Ao 57. Wattez JS, Ravallec R, Cudennec B, Knauf C, Dhulster P, Valet P, Breton C, Vieau D, Lesage J.2013. Apelin stimulates both cholecystokinin and glucagon-like peptide 1 secretions in vitro and in vivo in rodents. Peptides. Oct;48:134-6.

Ao 58. Drougard A, Duparc T, Brenachot X, Carneiro L, Gouazé A, Fournel A, Geurts L, Cadoudal T, Prats AC, Pénicaud L, Vieau D, Lesage J, Leloup C, Benani A, Cani PD, Valet P, Knauf C.2014. Hypothalamic Apelin/Reactive Oxygen Species Signaling Controls Hepatic Glucose Metabolism in the Onset of Diabetes. .Antioxid Redox Signal. 20 : 557-573.

Ao 59. Wattez JS, Delahaye F, Barella LF, Dickes-Coopman A, Montel V, Breton C, Mathias P, Foligné B, Lesage J, Vieau D. 2014. Short- and long-term effects of maternal perinatal undernutrition are lowered by cross-fostering during lactation in the male rat. J. Dev. Orig. Health Dis. Doi: 10.1017/S2040174413000548: 1-12.

Ao 60. Elmhiri G, Barella LF, Vieau D, Camous S, Mathias PC, Abdennebi-Najar L. 2014. Acute exposure to a precursor of Advanced Glycation End Products induces a dual effect on the rat pancreatic islet function. Int Journal Endocrinol 2014:378284.

Ao 61. Wattez JS, Delmont A, Bouvet M, Beseme O, Goers S, Delahaye F, Laborie C, Lesage J, Foligné B, Breton C, Metges C, Vieau D, Pinet . 2015. Maternal perinatal undernutrition modifies lactose and serotransferrin in milk: relevance to the programming of metabolic diseases? Am J Physiol Endocrinol Metab, 308 : E393-E401. Dernier auteur ex aequo.

Ao 62. Malta A, de Moura EG, Ribeiro TA, Tófolo LP, Abdennebi-Najar L, Vieau D, Barella LF, de Freitas Mathias PC, Lisboa PC, de Oliveira JC. 2016. Protein-energy malnutrition at mid-adulthood does not imprint long-term metabolic consequences in male rats. Eur J Nutr. 55(4):1423-33.

Ao 63. Mayeur S, Wattez JS, Lukaszewski MA, Lecoutre S, Butruille L, Drougard A, Eberlé D, Bastide B, Laborie C, Storme L, Knauf C, Vieau D, Breton C, Lesage J. 2016. Apelin Controls Fetal and Neonatal Glucose Homeostasis and Is Altered by Maternal Undernutrition. Diabetes. 65(3):554-60.

Ao 64. Lecoutre S, Deracinois B, Laborie C, Eberlé D, Guinez C, Panchenko PE, Lesage J, Vieau D, Junien C, Gabory A, Breton C. 2016. Depot- and sex-specific effects of maternal obesity in offspring's adipose tissue. J Endocrinol 230 : 39-53.

Ao 65. Lecoutre S, Marousez L, Drougard A, Knauf C, Guinez C, Eberlé D, Laborie C, Vieau D, Lesage J, Breton C. 2017. Maternal undernutrition programs the apelinergic system of adipose tissue in adult male rat offspring. J Dev Orig Health Dis. Feb;8(1):3-7.

Ao 66. Marciniak E, Leboucher A, Caron E, Ahmed T, Tailleux A, Dumont J, Issad T, Gerhardt E, Pagesy E, Vileno M, Bournonville C, Hamdane M, Bantubungi K, Lancel S, Demeyer D, Eddarkaoui S, Vallez E, Vieau D, Humez S, Faivre E, Grenier-Boley B, Outeiro TF, Staels B, Amouyel P, Balschun D, Buee L, Blum D. 2017. Tau deletion promotes brain insulin resistance. J Exp Med.214 (8): 2257-2269.
Ao 67. Lecoutre S, Oger F, Butruille L, Marousez L, Dickes-Coopman A, Pourpe C, Laborie C, Eberlé D, Guinez C, Lesage J, Vieau D, Junien C, Gabory A, Eeckhoute J, Breton C. 2017. Maternal obesity affects leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner. Molecular Metab.6 (8): 922-930.
Ao 68. Lecoutre S, Pourpe C, Butruille L, Marousez L, Laborie C, Guinez C, Lesage J, Vieau D, Eeckhoute J, Gabory A, Oger F, Eberle D, Breton C. 2018. Reduced PPARgamma 2 expression in adipose tissue of male rat offspring from obese dams is associated with epigenetic modifications. Faseb J. Jan 2. pii: fj.201700997R. doi: 10.1096/fj.201700997R.
Ao 69. Cissé O, Fajardy I, Delahaye F, Dickes A, Montel V, Moitrot E, Breton C, Vieau D, Laborie C. 2018. Effect of diet in females (F1) from prenatally undernourished mothers on metabolism and liver function in the F2 progeny is sex-specific. Eur J Nutr. doi: 10.1007/s00394-018-1794-y.

Ao 70. Leboucher A, Ahmed T, Caron E, Tailleux A, Raison S, Joly-Amado A, Marciniak E, Carvalho K, Hamdane M, Bantubungi K, Lancel S, Eddarkaoui S, Caillierez R, Vallez E, Staels B, Vieau D, Balschun D, Buee L, Blum D. 2019. Brain insulin response and peripheral metabolic changes in a Tau transgenic mouse model. Neurobiol Dis. 125:14-22.

Reviews and chapters of books

R1. Vieau D, Gicquel C et Proeschel MF. 1991. La proopiomélanocortine et ses fragments : applications à l’investigation clinique. Médecine Sciences; 7: 918-926.
R2. Day R, Vieau D and Seidah NG. 1994. Approaches in the study of the posttranslational processing of opioid peptide precursors : focus on prodynorphin. Regul. Peptides; 54 : 77-78.
R3. Raffin-Sanson ML, Vieau D, de Keyzer Y et Bertagna X. 1995. Hormones corticolipotropes et endorphines. Encyclopédie Médico-chirurgicale.
R 4. de Keyzer Y, Vieau D, Picon A and Bertagna X. 1996. Molecular aspects of the ectopic ACTH syndrome. Endocrine-Related Cancer; 3 : 99-112.
R5. Tostivint H, Lihrmann I, Bucharles C, Vieau D, Coulouarn Y, Fournier A, Conlon JM, Vaudry H, Dournaud P, Gardette R, Viollet C et Epelbaum J. 1996. Un deuxième gène codant pour la somatostatine est exprimé dans le cerveau. Médecine Sciences; 12 : 1131-1133.
R6. Chartrel N, Braun B, Collin F, Pierreuse B, Coulouarn Y, Tostivint H, Jeandel L, Trabucchi M, Vieau D, Lihrmann I, Tonon MC, Anouar Y, Conlon JM et Vaudry H. 1998. Stratégie d’identification de nouveaux neuropeptides. CR. Soc. Biol.; 192 : 619-638.
R7. Tostivint H, Lihrmann I, Bucharles C, Vieau D, Coulouarn Y, Boutelet I, Fournier A, Conlon JM, Vaudry H. 1998. A second somatostatin gene is expressed in the brain of the frog Rana ridibunda . Trends in Comparative Endocrinology and Neurobiology. Annals of the New York Academy of sciences 839: 496-497.

R8. Salzet M, Vieau D and Stefano G. 1999. Serpins : a survival strategy in immunity. Immunol. Today ; 20 : 541-544. Ce journal est devenu Trends in Immunology.
R9. Salzet M, Vieau D and Day R. 2000. Crosstalk between nervous and immune systems through the animal kingdom : focus on opioids. Trends in Neuroscience; 23 : 550-555.
R10. Tasiemski A, Lefebvre C, Vieau D and Salzet M. 2000. Immune response stimulation pathway : implications of opioid peptides. Crit. Trends in Immunol.; 2 : 209-216.
R11. Salzet M, Deloffre L, Breton C, Vieau D and Schoofs L. 2001. The angiotensin system elements in invertebrates. Brain Res. Rev. ; 36 : 35-45.
R12. Gangnon F, Danger JM, Jégou S, Vieau D, Vaudry H. 2002. Characterization of the three prohormone-convertases potentially involved in the processing of neuropeptide precursors in the european green frog. Proceedings of the 21st Conference of European Comparative Endocrinologists : 507-512.
R13. Gangnon F, Vieau D, Jégou S and Vaudry H. 2003. Cloning of the cDNA and comparative distribution of frog PC1 and PC2, the major proteolytic enzymes involved in the processing of neuropeptides. Recent Progress in Comparative Endocrinology and Neurobiology.
R14. Chartrel N, Braun B, Desrues L, Yon L, Vieau D, Kodjo M, Cellier E, Kikuyama S, Delarue C, Tonon MC and Vaudry H. 2003. Identification of novel neuropeptides from the amphibian brain. Recent Progress in Comparative Endocrinology and Neurobiology.
R15. Salzet M., Vieau, D., Breton, C. 2004. Cell signalling in prokaryotes and lower metazoa. (Ed. Fairweather I), Kluwer Publisher. Evidence for an annelid neuroendocrine system (Chapter 9).
R16. Lesage J, Sebaai N, Léonhardt M, Dutriez-Casteloot I, Breton C, Deloof S, Vieau D. 2006. Maternal undernutrition and HPA axis in the offspring. Stress ; 9 : 183-198.
R17. Vieau D, Sebaai N, Léonhardt M, Dutriez-Casteloot I, Molendi-Coste O, Laborie C, Breton C, Deloof S, Lesage J. 2007. HPA axis programming by maternal undernutrition in the male rat offspring. Psychoneuroendocrinology 32 (supl 1): S16-S20.
R18. Vieau D, Mayeur S, Lukaszewski MA, Delahaye F, Dutriez-Casteloot I, Laborie C, Deloof, S, Lesage J, Breton C. 2009. Perinatal undernutrition and brain derived nerve factor. The International Handbook of behavior, diet and nutrition.
R19. Vieau D. 2009. La dénutrition maternelle programme les systèmes neuroendocriniens impliqués dans la réponse au stress chez le rat mâle adulte : rôle dans la genèse du syndrome métabolique ? Médecine et nutrition 45 (1) : 1-6.
R20. Vieau D. 2009. Maternal undernutrition programs hypothalamo-pituitary-adrenal (HPA) axis activity. Endocrinologia & Diabetes Clinica e experimental 9 (4): 1068-1070.
R21. Mayeur S., Lukaszewski M.A., Breton C., Storme L., Vieau D., Lesage J. 2011. Do neurotrophins regulate the feto-placental development? Med. Hypotheses 76: 726-8.
R22. Vieau D. 2011. Perinatal nutritional programming of health and metabolic adult disease. World J Diabetes 2: 133-6.
R23. Mayeur S., Lukaszewski M.A., Breton C., Storme L., Junien C., Vieau D., Lesage J.  2011. BDNF in feto-placental development. Med. Sci. (Paris) 27: 251-2.
R 24. Guillemot J., Laborie C., Dutriez-Casteloot I., Maron M., Deloof S., Lesage J., Breton C., Vieau  D. 2011. Could maternal perinatal atypical antipsychotic treatments program later metabolic diseases in the offspring? Eur. J. Pharmacol. 667: 13-6.
R25. Lukaszewski M.A., Delahaye F., Vieau D., Breton C. 2012. Is the adipose tissue a key target of developmental programming of adult adiposity by maternal undernutrition? Adipocyte 1:64-7.
R26. Wattez J.S., Delahaye F., Lukaszewski M.A., Eberlé D., Vieau D., Breton C. 2013. Maternal nutrition programs hypothalamic POMC neurons in the offspring. Horm. Metab. Res. 45: 980-990.
    R27. Vieau D., Breton C., Dutriez-Casteloot I., Montel V., Dickes-Coopman A., Deloof S., Lesage J., Laborie C. 2011. Maternal perinatal undernutrition programs stress neuroendocrine systems in the male rat. Lee JE. Undernutrition: Effects, Causes and Management. Hauppage, New York: Nova Science Publishers, 1-23.
    R28. Vieau D., Mayeur S., Dutriez-Casteloot I., Lukaszewski M.A., Delahaye F.,  Laborie C., Deloof S., Lesage J., Breton C. 2013. Perinatal undernutrition and brain derived factor. International Handbook of Behavior, Diet and Nutrition (Preedy V.R., eds.), Springer.
R29. Lukaszewski MA, Eberlé D, Vieau D, Breton C. 2013. Nutritional manipulations in the perinatal period program adipose tissue in offspring. Am J Physiol Endocrinol Metab. 305 : E1195-E1207.

R30. Vieau D, Laborie C, Eberlé D, Lesage J, Breton C. 2016. Nutrition périnatale et programmation : le tissu adipeux est en dans le collimateur. Médecine Sciences 32 : 81-84.

R31. Vercruysse P, Vieau D, Blum D, Petersen A, Dupuis L. 2018. Hypothalamic alterations in neurodegenerative diseases and their relation to abnormal energy metabolism. Front. Mol. Neurosci. 11:2. doi: 10.3389/fnmol.2018.00002.

R32. Gratuze M, Joly-Amado A, Vieau D, Buée L, Blum D. 2018. Mutual relationship between Tau and central insulin signalling: consequences for Alzheimer disease and Tauopathies. Neuroendocrinology 107(2):181-195.

R33. Cellai L, Carvalho K, Faivre E, Deleau A, Vieau D, Buée L, Blum D, Mériaux C, Gomez Murcia V. 2018. The adenosinergic signaling : a complex but promising therapeutic target for Alzheimer’s disease. Front. Neurosci. 12:520.

R34. Joly-Amado A, Gratuze M, Benderradji H, Vieau D, Buée L, Blum D. 2018. Brain insulin signaling and Tau: impact for Alzheimer's disease and Tauopathies. Med Sci (Paris). 2018 Nov;34(11):929-935.

Research Interest: Medicinal Herbs, Behavioral Pharmacology, Neurodegeneration, Neurotransmitters, Neuroscience, Diabetes, Inflammation

Research Interest: Kidney transplantation, glomerular disease and pathological basics of the diseases

Research Interest: Own Publications in Different Areas of Health, among them Obesity and Metabolic Syndrome which is a Major Focus of Interest, Pricipalmente when Combined with Physical Exercises. 

Research Interest: Has Experience in Physical Therapy, with an Emphasis on Cardiopulmonary Physical Therapy, Acting on the Following Topics: Health Promotion, Cardiac Rehabilitation, Exercise Prescription for People with Special Needs, Assessment of Autonomic Function, Analysis of Biological Signals, Cardiorespiratory Physiotherapy in Morbid Obesity and Physical Therapy in Intensive Care. 

Dr. Ahed J Alkhatib is currently working as a researcher in Department of Forensic Science and Toxicology, Jordan University of Sciences and Technology, Jordon from 2011 to till date. He completed his PhD in Campbell University, medical technology, North Carolina, USA from 2008 to 2011. Dr. Ahed J Alkhatib is a member of council of nutritional and environmental disease (CONEM). He is conducting research that generates new theories. Dr. Ahed J Alkhatib has done 116 Publications. He is establishing new science (molecular sociology).

Research Interest:  Neurology; Pharmacology; diabetes; Philosophy of science; Tumor research; Behavioral biology; Emergency medicine

List of Publications:

1-    Amro Saleem Falah Alamaren and Ahed J. Alkhatib (2019). The Relationship Between Financial Stability and Insurance. International Business Management, 13: 130-133.

2-    Ahed J Alkhatib (2019). Expression and Releasing of Cell Cycle Proteins by Candida albicans into Surrounding Tissue: New Perspectives of the Relationship between Microbes and Host. EC Microbiology, 15 (3): 168-171.

3-     Samirah Fahad A, Ahed Alkhatib (2019). The Assessment of Intervention Programs for Autism Including Children and their Parents. Am J Biomed Sci & Res., 1(6): 236-238. AJBSR.MS.ID.000553.

4-    Kawther Faisal Amawi, Inas Saleh Al-Mazari, Ali Alsarhan, Hamza Qasim Mohammad Alhamad, Ahed J. Alkhatib (2019). Diabetes upregulates the expression of HSP90 and downregulates HSP70 in the liver of diabetic rats. Comparative Clinical Pathology, 28 (2): 473-478.

5-    Ahed J. Alkhatib (2019). The Progression of a Disease Depends on Downregulation of Heat Shock Protein 70 (HSP70) And Upregulation of Inducible Nitric Oxide Synthase (iNOS): A New Medical Hypothesis. Biomed Discoveries: 1-3, DOI: 10.29011/ BMDC-103. 100003.

6-    Mohammad A. Bani-Ahmad, Suleimman A. Al-Sweedan, Mohammad A. Al-Asseiri, Ahed J. Alkhatib (2018). A Proposed Kinetic Model for the Diagnostic and Prognostic Value of WT1 and p53 in Acute Myeloid Leukemia. Clinical laboratory, 64 (3):357-363. doi: 10.7754/Clin.Lab.2017.170915.

7-    Ahed J Alkhatib, Ilham Ahed Alkhatib (2018). Metformin and Urtica pilulifera: Comparable Effects and Similar Actions in Diabetes. Int J Pharm,  8(3): 1-2.

8-    Ahed J Alkhatib (2018). White Matter Ageing: Etiology and Prognosis. Appl Cell Biol, 6 (2), 14-17.
 
9-    Khaled Z. Alawneh, Liqaa A. Raffee, Haytham A. Al Ewaidat and Ahed J. Alkhatib (2018).. The Impact of Exposure to Medical Radiation on Lead (Pb+2) and Thyroid Function Test. Research Journal of Medical Sciences, 12: 31-34.

10-    Hani A. Masaadeh, Ali Alrifai, Ahed J Alkhatib and Mamdoh Meqdam (2018). Molecular Epidemiology of Extended-Spectrum β-Lactamase-ProducingK. pneumoniae in Northern Jordan. Research Journal of Medical Sciences, 12: 63-69.

11-    Ahed J Alkhatib (2018). Does Epstein - Barr Virus Cross Talks with Sex Hormone Receptors on Lymphoid Cells Differently to Produce Lymphoma? Int J Pharm, 8(1): 56-57.

12-    Ahed J Alkhatib (2018). Non-classical Roles of Microbes.  PSM Microbiol., 3(2): 62-63.

13-    Sani S Bala, Ahed J Alkhatib, SS Bashir, Abdulhadi M (2018). Photocatalytic Degradation of Indigo Carmine in Aqueous Solutions by the Antibacterial Agent Pefloxacin and UVA. Biomed J Sci&Tech Res 5(5), DOI: 10.26717/ BJSTR.2018.05.001275.

14-    Sonia Cherian, Ahed J Alkhatib, Megha Aggarwal (2018). Relationship between organizational commitment and job satisfaction of nurses in Dubai hospital. Journal of Advances in Social Science and Humanities, 4(1): 36373-36400.

15-    Amro Saleem Falah Alamaren, Ahed J Alkhatib (2018). Financial Aspects Associated with Overuse of Health Resources. Biomed J Sci&Tech Res 7(1). BJSTR. MS.ID.001444. DOI: 10.26717/ BJSTR.2018.07.001444.

16-    Ahed J Alkhatib, Khalid Alzaailay (2018). The Appropriate Use of Activated Charcoal in Pharmaceutical and Toxicological Approaches. Biomed J Sci & Tech Res, 5 (2),

17-    Ahed J Alkatib (2017). Diabetes and diabetic neuropathies are independent events: a new medical hypothesis. Ind Res J Pharm & Sci, 4 (3): 1064-1067.


18-    Ahed J Alkhatib (2019). The Use of Crude Extract of Alhagi graecorum and Urtica pilulifera in the Treatment of Chronic Inflammation of Seminal Fluid: A Case Study. Open Acc J Comp & Alt Med 1(4): 62-64.

19-    Ahed J Alkhatib (2019). New Insights to Diabetes: Is Diabetes a Metabolic Disorder or a Neurological Disease? International Journal of Diabetes & Metabolic Disorders, 4 (1).

20-    Ahed J Alkhatib (2019). White Matter: Structural and Functional Roles in Health and Disease. PSM Biological Research, 4 (1): 17-19.

21-    Ahed J Alkhatib (2018). The role of natural antioxidants in declining memory defects in Alzheimer’s disease. J Spine Neurosurg, 7, DOI: 10.4172/2325-9701-C7-030.

22-    Alkhatib, A. J., (2018). Crude Extract of Potato Ameliorates Clinical Impacts of Infection with Helicobacter pylori: Case Study. PSM Microbiol. 3(2): 64-66.

23-    Ahed J Alkhatib (2018). It is time to change the concept of herbal use to molecular food. Ind Res J Pharm & Sci, 5 (4): 1648.

24-    Ahed J Alkhatib, Ilham Ahed Alkhatib, Kawther Faisal Amawi, Ali Alsarhan, Suha K Ababneh (2018). Sickle cell disease: molecular and pathophysiological features. Ind Res J Pharm & Sci, 5 (1), 1251-1259.

25-    Ahed J Alkhatib, Nayef Alzame (2018). Neurotoxicity and criminal behavior. Indian research journal of pharmacy and science, 5 (2): DOI: 1234-1238. 10.26717/BJSTR.2018.05.001170.

26-    Ahed J Alkhatib (2018). WHITE MATTER ASSOCIATED DISEASES.  Indian research journal of pharmacy and science, 5 (2): 1416-1419.

27-    Ahed J Alkhatib, Sani S. Bala, S.S. Bashir, Abdulhadi M (2018). Chemical and pharmaceutical properties of pefloxacin: a review. Indian research journal of pharmacy and science, 5 (2): 1427-1431.

28-    Mohamad M J Mohamad, Mustafa Al-Shehabat, Issa Ahmad AlShehabat, Ahed J Alkhatib (2018). The variations in altitude predict angiotensin ii and blood pressure variables in Jordan. Indian research journal of pharmacy and science, 5 (2): 1449-1455.


29-    Ahed J Alkhatib (2018). New Perspectives of Autoimmunity Diseases and Microbiome: Etiology and Treatment. Acta Scientific Pharmaceutical Sciences, 2(10): 12-14.

30-    Ahed J Alkhatib (2017). White Matter and Disease: Does Brain have a Role in Initiating Diseases. Brain Disorders & Therapy, 6: e124. doi: 10.4172/2168-975X.1000e124.

Research Interest: Obesity, Mind and Inhibitory Control, Metabolic Syndrome, Rationale, Cardiovascular Disease 

Research Interest: He Also Conducted Basic Research in Regard to the Investigation of the Role of Immunological Aspects in Kidney Diseases Including Nephritic Syndrome and Diabetic Nephropathy.

Research Interest: Area of Gastrointestinal Cancer and Inflammatory Bowel Disease. 

China Diabetes Impact Study is funded by IDF and technically supported by Division of Diabetes Translation of CDC. It is a follow-up study of China National Diabetes and Metabolic Disorder Study. A total of 12 study sites participated in the China Diabetes Impact Study. I am the national program coordinator and the investigator of Beijing study site. All study participants with DM, NDM and IGR were interviewed and collected information about their health care service use, medical expenditure, etc. 

Research Interest: Directed Toward the Idenfication of Bioactive Compound, the Total Synthesis, and Structural Modification of Natural Products from Chinese Herds, Drug Design and Synthesis Based on Natural Lead Compounds, Mechanism Study of Natural Products, Peptide Investigation Initiated from Natural Resources, the Interface of Organic Chemistry and Cell Biology.

Research Interest: Metabolic and Bariatric Surgery, Gastrointestinal Surgery, Thyroid Surgery, Hepatobiliary Surgery, Hernia Surgery, Anorectal Surgery, General Surgery.

Research Interest: Molecular Pharmacology, Chinese Medicines and Diabetes Mellitus, Effects and Mechanism of Natural Products on Cardio-Cerebrovascular Disease.

Research Interest: Internal Medicine and Cardiology

Research Interest: Application of Multiple Linear and Logistic Regression Models, Applied Longitudinal Data Analysis, Generalized Linear and Non-Linear Mixed Models, and Survival Analysis; Epidemiology of Chronic Diseases Including Alcohol use Disorders and Drug Abuse, Alzheimer’s Disease, Cancer, Obesity and Diabetes, Heart Disease and Stroke; Genetic Epidemiology of Complex Diseases Including Alcohol Dependence And Comorbidity, Obesity, Diabetes and Related Conditions, Depression and Schizophrenia.

Research Interest: Nutrition, Weight management, Obesity Evaluation, Behavior Change Interventions, Critical Thinking, Health Disparity, Curriculum and Program Development, Type 2 Diabetes

Dr. Mehta’s research program focuses on the role of innate immunity and inflammation in the development of cardiovascular and metabolic diseases. Using a trans-disciplinary approach that involves genetic epidemiology, translational medicine, and novel cardiovascular imaging approaches, Dr. Mehta and his team study how inflammation affects insulin resistance, the development of metabolic syndrome, and lipoprotein dysfunction, all of which are risk factors for atherosclerosis and subsequent cardiovascular disease (CVD).

Research Interest: Obesity, Chronic Hronic Inflammation, Inflammatory Disease, Cancer

Research Interest: Nutrition, Obesity, Weight, Diet

Research Interest: Cardiovascular Disease, Electrophysiology, Pacemaker, ICD and CRT Therapy, Metabolic Syndrome, Bidirectional Effect of CVD and CKD

Research Interest: Epidemiology, pathogenesis, diagnosis and treatment of fatty liver (metabolic and viral); genetic determinants of fatty liver; metabolic syndrome; insulin resistance; association between fatty liver, metabolic syndrome, diabetes and cardiovascular diseases;  liver ultrasonography.

Research Interest: It is Mainly Lies in Two Areas. First I Focused on Applying Statistical Methods and Multilevel Modeling in Randomized Clinical Trials and Family-Based Health-Related Interventions, Particularly in Substance Abuse, HIV/AIDS, STD, Sexual Risk Behaviors and Minority Health Disparities. Second, I am Interested in Epidemiology Studies 0f Chronic Disease Including Alcohol Use Disorder, Drug Abuse, Obesity, Diabetes, Metabolic Syndrome, Hypertension, Cardiovascular Disease and Stroke; and Also from Genetic Epidemiology Point of View to Examine Complex Disease Including Alcohol Dependence and Co-Morbidity, and Alzheimer Disease Etc. 

Research Interest:

1. Obesity and metabolic diseases
2. Effect of sport in obesity and cardio-metabolic disturbances
3. Role of environmental pollutant in cardio-metabolic diseases

List of Publications:

1.    Della Guardia L, Shin AC. The role of adipose tissue dysfunction in PM2.5-induced vascular pathology. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H971-H972. doi: 10.1152/ajpheart.00156.2022
2.    De Nardi M, Bisio A, Della Guardia L, Facheris C, Faelli E, La Torre A, Luzi L, Ruggeri P, Codella R. Partial-Body Cryostimulation Increases Resting Energy Expenditure in Lean and Obese Women. Int J Environ Res Public Health. 2021 Apr 14;18(8):4127. doi: 10.3390/ijerph18084127.
3.    Della Guardia L, Shin AC. White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure. J Mol Med (Berl). 2022 May;100(5):665-676. doi: 10.1007/s00109-022-02183-6. Epub 2022 Mar 14
4.    Della Guardia L, Codella R. Exercise tolls the bell for key mediators of low-grade inflammation in dysmetabolic conditions. Cytokine Growth Factor Rev. 2021 Dec;62:83-93. doi: 10.1016/j.cytogfr.2021.09.003.
5.    Codella R, Della Guardia L, Terruzzi I, Solini A, Folli F, Varoni EM, Carrassi A, Luzi L. Physical activity as a proxy to ameliorate inflammation in patients with type 2 diabetes and periodontal disease at high cardiovascular risk. Nutr Metab Cardiovasc Dis. 2021 Jul 22;31(8):2199-2209. doi: 10.1016/j.numecd.2021.04.022.
6.    Della Guardia L, Codella R. Airways to heaven: Caution needed when exercising during COVID-19. Med Hypotheses. 2021 Mar;148:110522. doi: 10.1016/j.mehy.2021.110522.
7.    Moreno C, Della Guardia L, Shnyder V et al. iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signal. Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.
8.    Maurizi G, Babini L, Della Gaurdia L. Potential role of microRNAs in the regulation of adipocytes liposecretion and adipose tissue physiology. Journal of Cellular Physiology.
9.    Della Guardia L, Thomas MA, Cena H. Insulin Sensitivity and Glucose Homeostasis Can Be Influenced by Metabolic Acid Load. Nutrients 2018, 10, 618; doi:10.3390/nu10050618
10.    Maurizi G, Petäistö T, Maurizi A, Della Guardia L. Key-genes regulating the liposecretion process of mature adipocytes. J Cell Physiol. 2018 May;233(5):3784-3793.
11.    Manuelli M, Della Guardia L, Cena H. Enriching Diet with n-3 PUFAs to Help Prevent Cardiovascular Diseases in Healthy Adults: Results from Clinical Trials. Int J Mol Sci. 2017 Jul 18;18(7)
12.    Maurizi G, Della Guardia L, Maurizi A, Poloni A. Adipocytes properties and crosstalk with immune system in obesity-related inflammation. J Cell Physiol. 2018;233:88–97.
13.    Della Guardia L, Roggi C, Cena H. Diet-induced acidosis and alkali supplementation. Int J Food Sci Nutr. 2016 Jun 24:1-8.
14.    Della Guardia L, Cavallaro M, Cena H. The risks of self-made diets: the case of an amateur bodybuilder. J Int Soc Sports Nutr. 2015 Apr 1;12:16.
15.    Della Guardia L. Guarene M. Calcaterra V Vandoni M Cena H. Effects of a multidisciplinary intervention on childhood obesity". 2nd N&G conference Barcelona. 30 Jen-2 Feb 2014.
16.    Guarene M. Calcaterra V, De Giuseppe R, Della Guardia L, et al. Lifestyle, nutritional Knowledge and fears of a group of adolescents suffering from type 1 diabetes. Clin Nutr 2014 Sep (Supp); 33:S174

Research Interest: My Research Interests Span Many Areas Including Bioinformatics and Metabolomics. As a Phd Student at Center of Magnetic Resonance of University of Florence (Italy), My Research Focused on the Metabolomic Analysis of Biofluid (E.G., Urine, Serum, Saliva) and Tissue (E.G., Intact Human Liver) Samples. I Used Nuclear Magnetic Resonance (NMR) Spectroscopy and Advanced Statistical Analysis Techniques to Identify and Predict Metabolomic Fingerprints. In Particular, I Used NMR-Based Metabolomic Analysis to Identify a Fingerprint of Poor-Survival in the Serum of Patient with Metastatic Colorectal Cancer.
Now as Postdoc at Dana-Farber Cancer Institute, My Current Research Focuses on Identifying Metabolic Fingerprint Predictors of Prostate Cancer Development and Progression to Improve our Understanding of The Mechanisms Linking Metabolism with the Biology of Prostate Cancer. Moreover, I Will Contribute on Developing of New Standard Operation Procedures for Metabolomic Analysis in Formalin Fixed Paraffin Embedded Tissues. 

Research Interest: Multicenter Prospective Observational CREST Study (U.Penn, Vanderbilt, and University Hospitals Case Medical Center) with Dr. James Fang, Evaluating Cardiotoxicity of Sunitinib in Metastatic Renal Cell Carcinoma Using Tonometry Data

Research Interest: A Biomedical Researcher with a Focus on Neurobehavioral, Metabolic and Endocrine Disorders.

Research Interest: He has Vast Experience in Characterization of New Chemical Entities (NCE’S) for Early Stage Dosage form Development, Preparation of Nano Particles, Spray Dried Powders, Solubility Screening, Bio-Availability Enhancement, Granulation and Fluid Bed Drying, Compression Using Rotary Tablet Press, Coating, Stability Studies and Tech Transfer Etc.

Research Interest: Blood Brain Barrier; Neurovascular Pharmacokinetics; Stroke; Ischemia; Neurodegneration; Neuroprotection; Neuropharmacology; Nutrient and Ion Transporters; Diabetes

Research Interest: My Research has Focused on Understanding the BBB, Changes that Occur in the Blood-Tumor-Barrier (BTB), and Drug Uptake Therein. To this End, I Have Worked and Gained Significant Amount of Knowledge on Factors Influencing Anticancer Delivery and Activity in Brain aBrain Metastases Developed from Breast Cancer in Mouse Models. These Include: (1) How BBB is Altered in Mouse Models of Brain Metastases of Breast Cancer. (2) Pharmacokinetic-Pharmacodynamic Relationship of Anticancer Drugs in Brain Metastases. (3) in Vitro- In Vivo Correlations (IVIVC) to Predict Optimum Therapeutic Concentrations for Treatment of Brain Metastases. (4) Improving Targeted Anticancer Drug Delivery to Brain Tumors by Inhibiting Efflux Transporters and Piggy Backing Drugs to Substrates of Influx Transporters at the BBB.

Research Interest: Immunology such as Autoimmune Diabetes (Type 1).