Research Interest: Multicenter Prospective Observational CREST Study (U.Penn, Vanderbilt, and University Hospitals Case Medical Center) with Dr. James Fang, Evaluating Cardiotoxicity of Sunitinib in Metastatic Renal Cell Carcinoma Using Tonometry Data

Research Interest: Cardiovascular Disease, Electrophysiology, Pacemaker, ICD and CRT Therapy, Metabolic Syndrome, Bidirectional Effect of CVD and CKD

Research Interest: Medicinal Herbs, Behavioral Pharmacology, Neurodegeneration, Neurotransmitters, Neuroscience, Diabetes, Inflammation

Research Interest: Blood Brain Barrier; Neurovascular Pharmacokinetics; Stroke; Ischemia; Neurodegneration; Neuroprotection; Neuropharmacology; Nutrient and Ion Transporters; Diabetes

China Diabetes Impact Study is funded by IDF and technically supported by Division of Diabetes Translation of CDC. It is a follow-up study of China National Diabetes and Metabolic Disorder Study. A total of 12 study sites participated in the China Diabetes Impact Study. I am the national program coordinator and the investigator of Beijing study site. All study participants with DM, NDM and IGR were interviewed and collected information about their health care service use, medical expenditure, etc. 

Research Interest: He Also Conducted Basic Research in Regard to the Investigation of the Role of Immunological Aspects in Kidney Diseases Including Nephritic Syndrome and Diabetic Nephropathy.

Research Interest: Cardiovascular diseases, Endothelial function, Hypertension, Diabetes, Renin-angiotensin-system

Research Interest: Epidemiology, pathogenesis, diagnosis and treatment of fatty liver (metabolic and viral); genetic determinants of fatty liver; metabolic syndrome; insulin resistance; association between fatty liver, metabolic syndrome, diabetes and cardiovascular diseases;  liver ultrasonography.

Research Interest: Epidemiology of Diabetes; Mechanism of Insulin Action; Insulin Resistance; Obesity and Insulin Resistance; Cardiovascular Risk Diabetes and Obesity; Bone Metabolism and Diabetes and Obesity; Gene Adiposities Tissue in Diabetes and Obesity. 

Research Interest: Has Experience in Physical Therapy, with an Emphasis on Cardiopulmonary Physical Therapy, Acting on the Following Topics: Health Promotion, Cardiac Rehabilitation, Exercise Prescription for People with Special Needs, Assessment of Autonomic Function, Analysis of Biological Signals, Cardiorespiratory Physiotherapy in Morbid Obesity and Physical Therapy in Intensive Care. 

Research Interest: He has Vast Experience in Characterization of New Chemical Entities (NCE’S) for Early Stage Dosage form Development, Preparation of Nano Particles, Spray Dried Powders, Solubility Screening, Bio-Availability Enhancement, Granulation and Fluid Bed Drying, Compression Using Rotary Tablet Press, Coating, Stability Studies and Tech Transfer Etc.

Research Interest:

1. Obesity and metabolic diseases
2. Effect of sport in obesity and cardio-metabolic disturbances
3. Role of environmental pollutant in cardio-metabolic diseases

List of Publications:

1.    Della Guardia L, Shin AC. The role of adipose tissue dysfunction in PM2.5-induced vascular pathology. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H971-H972. doi: 10.1152/ajpheart.00156.2022
2.    De Nardi M, Bisio A, Della Guardia L, Facheris C, Faelli E, La Torre A, Luzi L, Ruggeri P, Codella R. Partial-Body Cryostimulation Increases Resting Energy Expenditure in Lean and Obese Women. Int J Environ Res Public Health. 2021 Apr 14;18(8):4127. doi: 10.3390/ijerph18084127.
3.    Della Guardia L, Shin AC. White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure. J Mol Med (Berl). 2022 May;100(5):665-676. doi: 10.1007/s00109-022-02183-6. Epub 2022 Mar 14
4.    Della Guardia L, Codella R. Exercise tolls the bell for key mediators of low-grade inflammation in dysmetabolic conditions. Cytokine Growth Factor Rev. 2021 Dec;62:83-93. doi: 10.1016/j.cytogfr.2021.09.003.
5.    Codella R, Della Guardia L, Terruzzi I, Solini A, Folli F, Varoni EM, Carrassi A, Luzi L. Physical activity as a proxy to ameliorate inflammation in patients with type 2 diabetes and periodontal disease at high cardiovascular risk. Nutr Metab Cardiovasc Dis. 2021 Jul 22;31(8):2199-2209. doi: 10.1016/j.numecd.2021.04.022.
6.    Della Guardia L, Codella R. Airways to heaven: Caution needed when exercising during COVID-19. Med Hypotheses. 2021 Mar;148:110522. doi: 10.1016/j.mehy.2021.110522.
7.    Moreno C, Della Guardia L, Shnyder V et al. iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signal. Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.
8.    Maurizi G, Babini L, Della Gaurdia L. Potential role of microRNAs in the regulation of adipocytes liposecretion and adipose tissue physiology. Journal of Cellular Physiology.
9.    Della Guardia L, Thomas MA, Cena H. Insulin Sensitivity and Glucose Homeostasis Can Be Influenced by Metabolic Acid Load. Nutrients 2018, 10, 618; doi:10.3390/nu10050618
10.    Maurizi G, Petäistö T, Maurizi A, Della Guardia L. Key-genes regulating the liposecretion process of mature adipocytes. J Cell Physiol. 2018 May;233(5):3784-3793.
11.    Manuelli M, Della Guardia L, Cena H. Enriching Diet with n-3 PUFAs to Help Prevent Cardiovascular Diseases in Healthy Adults: Results from Clinical Trials. Int J Mol Sci. 2017 Jul 18;18(7)
12.    Maurizi G, Della Guardia L, Maurizi A, Poloni A. Adipocytes properties and crosstalk with immune system in obesity-related inflammation. J Cell Physiol. 2018;233:88–97.
13.    Della Guardia L, Roggi C, Cena H. Diet-induced acidosis and alkali supplementation. Int J Food Sci Nutr. 2016 Jun 24:1-8.
14.    Della Guardia L, Cavallaro M, Cena H. The risks of self-made diets: the case of an amateur bodybuilder. J Int Soc Sports Nutr. 2015 Apr 1;12:16.
15.    Della Guardia L. Guarene M. Calcaterra V Vandoni M Cena H. Effects of a multidisciplinary intervention on childhood obesity". 2nd N&G conference Barcelona. 30 Jen-2 Feb 2014.
16.    Guarene M. Calcaterra V, De Giuseppe R, Della Guardia L, et al. Lifestyle, nutritional Knowledge and fears of a group of adolescents suffering from type 1 diabetes. Clin Nutr 2014 Sep (Supp); 33:S174

Dr. Mehta’s research program focuses on the role of innate immunity and inflammation in the development of cardiovascular and metabolic diseases. Using a trans-disciplinary approach that involves genetic epidemiology, translational medicine, and novel cardiovascular imaging approaches, Dr. Mehta and his team study how inflammation affects insulin resistance, the development of metabolic syndrome, and lipoprotein dysfunction, all of which are risk factors for atherosclerosis and subsequent cardiovascular disease (CVD).

Research Interest: Deep Specialization in Research Involve; Obesity and Associated Disorder, Its Mechanism and Treatment. Metabolic Syndrome-Food Additives and Its Effect on the Bodyorgans. Also the Biochemical, Oxidative Stress and Advanced Biomarkers in Health and Diseases. Recently Involved in Nanomedical Materials as Antioxidant for Health Maintainance.

Research Interest: Clinical Cardiology; Clinical Pharmacology; Cardiovascular Physiology; Arterial Hypertension; Blood Pressure Monitoring; Telemedicine.

2 Parati G, Ravogli A, Bragato R, OMBONI S, Mutti E, Mancia G. Clinical and hemodynamic effects of celiprolol in essential hypertension. J Cardiovasc Pharmacol 1989;7:S14-21.
3 Mancia G, Groppelli A, Casadei R, OMBONI S, Mutti E, Parati G. Cardiovascular effects of smoking. Clin Exp Hypertens A 1990;5:917-29.
4 Parati G, Castiglioni P, Di Rienzo M, OMBONI S, Pedotti A, Mancia G. Sequential spectral analysis of 24-hour blood pressure and pulse interval in humans. Hypertension 1990;4:414-21.
5 Groppelli A, OMBONI S, Parati G, Mancia G. Blood pressure and heart rate response to repeated smoking before and after beta-blockade and selective alpha 1 inhibition. J Hypertens Suppl 1990;5:S35-40.
6 Mutti E, Trazzi S, OMBONI S, Parati G, Mancia G. Effect of placebo on 24-h non-invasive ambulatory blood pressure. J Hypertens 1991;4:361-4.
7 Parati G, Trazzi S, Ravogli A, Casadei R, OMBONI S, Mancia G. Methodological problems in evaluation of cardiovascular effects of stress in humans. Hypertension 1991;4 Suppl:III50-5.
8 Groppelli A, OMBONI S, Ravogli A, Villani A, Parati G, Mancia G. Validation of the SpaceLabs 90202 and 90207 devices for ambulatory blood pressure monitoring by comparison with intra-arterial resting and ambulatory measurements. J Hypertens Suppl 1991;6:S334-5.
9 Trazzi S, OMBONI S, Mutti E, Parati G, Zanchetti A, Mancia G. Acute modulation of arterial compliance in mild essential hypertension. J Hypertens Suppl 1991;6:S110-1.
10 Zito M, Parati G, OMBONI S, Cervone C, Ulian L, D'Aviero M, Abate G, Mancia G. Effect of ageing on blood pressure variability. J Hypertens Suppl 1991;6:S328-9.
11 OMBONI S, Ravogli A, Parati G, Zanchetti A, Mancia G. Prognostic value of ambulatory blood pressure monitoring. J Hypertens Suppl 1991;3:S25-8.
12 Parati G, Groppelli A, OMBONI S, Trazzi S, Frattola A, Mancia G. Testing the accuracy of blood pressure monitoring devices in ambulatory conditions. J Hypertens Suppl 1991;8:S7-9.
13 Di Rienzo M, Parati G, Castiglioni P, OMBONI S, Ferrari AU, Ramirez AJ, Pedotti A, Mancia G. Role of sinoaortic afferents in modulating BP and pulse-interval spectral characteristics in unanesthetized cats. Am J Physiol 1991;6 Pt 2:H1811-8.
14 Groppelli A, Giorgi DM, OMBONI S, Parati G, Mancia G. Persistent blood pressure increase induced by heavy smoking. J Hypertens 1992;5:495-9.
15 Giannattasio C, Cattaneo BM, OMBONI S, Seravalle G, Bolla G, Turolo L, Morganti A, Grassi G, Zanchetti A, Mancia G. Sympathomoderating influence of benazepril in essential hypertension. J Hypertens 1992;4:373-8.
16 Mancia G, OMBONI S, Parati G, Trazzi S. Twenty-four hour blood pressure monitoring and end-organ damage. Blood Press Suppl 1992;1:38-41.
17 Mancia G, Frattola A, OMBONI S, Parati G, Rarogli A. Twenty-four-hour blood pressure and antihypertensive treatment. Blood Press Suppl 1992;1:44-5.
18 Parati G, OMBONI S, Di Rienzo M, Frattola A, Albini F, Mancia G. Twenty-four hour blood pressure variability:clinical implications. Kidney Int Suppl 1992;37:S24-8.
19 Groppelli A, OMBONI S, Parati G, Mancia G. Evaluation of noninvasive blood pressure monitoring devices Spacelabs 90202 and 90207 versus resting and ambulatory 24-hour intra-arterial blood pressure. Hypertension 1992;2:227-32.
20 Trazzi S, OMBONI S, Santucciu C, Parati G, Mancia G. Variability in arterial diameter and compliance:compliance modulation reserve. J Hypertens Suppl 1992;6:S41-3.
21 Villani A, Parati G, Groppelli A, OMBONI S, Di Rienzo M, Mancia G. Noninvasive automatic blood pressure monitoring does not attenuate nighttime hypotension. Evidence from 24 h intraarterial blood pressure monitoring. Am J Hypertens 1992;10:744-7.
22 Mancia G, OMBONI S, Ravogli A, Frattola A, Villani A. Ambulatory blood pressure monitoring. Drugs 1992;1:17-22.
23 OMBONI S, Frattola A, Parati G, Ravogli A, Mancia G. Clinical value of blood pressure measurements:focus on ambulatory blood pressures. Am J Cardiol. 1992;12:4D-8D.
24 Mancia G, OMBONI S, Parati G, Trazzi S, Mutti E. Limited reproducibility of hourly blood pressure values obtained by ambulatory blood pressure monitoring:implications for studies on antihypertensive drugs. J Hypertens 1992;12:1531-5.
25 OMBONI S, Ravogli A, Mancia G. Ambulatory blood pressure monitoring and antihypertensive treatment. J Hum Hypertens 1992;2:S9-13.
26 Mancia G, Giannattasio C, OMBONI S. Ambulatory blood pressure monitoring and antihypertensive treatment. Eur Heart J 1992;G:43-7.
27 Mancia G, De Cesaris R, Fogari R, Lattuada S, Montemurro G, Palombo C, Porcellati C, Ranieri G, Tettamanti F, Verdecchia P, Marelli C, OMBONI S, Ravogli A, Zanchetti A, for the Italian Trandolapril Study Group. Evaluation of the antihypertensive effect of once-a-day trandolapril by 24-hour ambulatory blood pressure monitoring. The Italian Trandolapril Study Group. Am J Cardiol 1992;70:60D-66D.
28 Laurent S, Hayoz D, Trazzi S, Boutouyrie P, Waeber B, OMBONI S, Brunner HR, Mancia G, Safar M. Isobaric compliance of the radial artery is increased in patients with essential hypertension. J Hypertens 1993;1:89-98.
29 Mancia G, OMBONI S, Parati G, Santucciu C, Trazzi S, Ulian L. Clinical value of ambulatory blood pressure monitoring. Am J Hypertens 1993;3 Pt 2:9S-13S.
30 Parati G, di Rienzo M, OMBONI S, Castiglioni P, Frattola A, Mancia G. Spectral analysis of 24 h blood pressure recordings. Am J Hypertens 1993;6 Pt 2:188S-193S.
31 Mancia G, OMBONI S, Parati G, Sega R, Trazzi S. Ambulatory blood pressure monitoring in the design of studies on antihypertensive drug efficacy. Am J Hypertens 1993;6 Pt 2:233S-235S.
32 OMBONI S, Parati G, Frattola A, Mutti E, Di Rienzo M, Castiglioni P, Mancia G. Spectral and sequence analysis of finger blood pressure variability. Comparison with analysis of intra-arterial recordings. Hypertension. 1993;1:26-33.

Zanchetti A, Bianchi L, Amigoni S, OMBONI S, Villani A, Ravogli A. Antihypertensive effects of nifedipine gastrointestinal therapeutic system on clinic and ambulatory blood pressure in essential hypertensives. Italian GITS Study Group. J Hypertens Suppl 1993;5:S334-5.
34 Pomidossi G, Saino A, Perondi R, Gregorini L, Alessio P, Rimini A, OMBONI S, Zanchetti A, Mancia G. Impairment of the arterial baroreflex during symptomatic and silent myocardial ischemia in humans. J Am Coll Cardiol 1993;7:1866-72.
35 Ravogli A, OMBONI S, De Cesaris R, Fogari R, Lattuada S, Montemurro G, Palombo C, Porcellati C, Ranieri G, Tettamanti C. Twenty-four-hour ambulatory blood pressure monitoring and antihypertensive treatment:focus on ACE inhibitors. J Cardiovasc Pharmacol 1994;1:S15-9.
36 Mancia G, OMBONI S, Parati G, Ravogli A, Sega R, Ulian L. Ambulatory blood pressure monitoring in the diagnosis of hypertension and evaluation of antihypertensive drug efficacy. Blood Press Suppl 1994;2:20-2.
37 Mancia G, Frattola A, Groppelli A, OMBONI S, Parati G, Ulian L, Villani A. Blood pressure reduction and end-organ damage in hypertension. J Hypertens Suppl 1994;8:S35-41.
38 Parati G, Ravogli A, Mutti E, Santucciu C, OMBONI S, Mancia G. Ambulatory blood pressure monitoring in the evaluation of antihypertensive drugs. J Hypertens Suppl 1994;8:S9-15.
39 OMBONI S, Smit AA, Wieling W. Twenty four hour continuous non-invasive finger blood pressure monitoring:a novel approach to the evaluation of treatment in patients with autonomic failure. Br Heart J 1995;3:290-2.
40 Mancia G, OMBONI S, Parati G, Ravogli A, Villani A, Zanchetti A. Lack of placebo effect on ambulatory blood pressure. Am J Hypertens 1995;3:311-5.
41 Mancia G, OMBONI S, Ravogli A, Parati G, Zanchetti A. Ambulatory blood pressure monitoring in the evaluation of antihypertensive treatment:additional information from a large data base. Blood Press 1995;3:148-56.
42 Parati G, Di Rienzo M, OMBONI S, Ulian L, Mancia G. Blood pressure variability over 24 hours:its different components and its relationship to the arterial baroreflex. J Sleep Res 1995;S1:21-29.
43 Mancia G, Giannattasio C, Turrini D, Grassi G, OMBONI S. Structural cardiovascular alterations and blood pressure variability in human hypertension. J Hypertens Suppl 1995;2:S7-14.
44 OMBONI S, Parati G, Zanchetti A, Mancia G. Calculation of trough:peak ratio of antihypertensive treatment from ambulatory blood pressure:methodological aspects. J Hypertens 1995;10:1105-12.
45 OMBONI S, Ravogli A, Villani A, Mancia G. Permanent blood pressure control over the 24 h by trandolapril. Am J Hypertens 1995;10 Pt 2:71S-74S.
46 Thijs L, Dabrowska E, Clement D, Fagard R, Laks T, Mancia G, O'Brien E, OMBONI S, Parati G, Staessen J, et al. Diurnal blood pressure profile in older patients with isolated systolic hypertension. The SYST-EUR Investigators. J Hum Hypertens 1995;11:917-24.
47 Parati G, Ulian L, Santucciu C, OMBONI S, Mancia G. Blood pressure variability, cardiovascular risk and antihypertensive treatment. J Hypertens Suppl 1995;4:S27-34.
48 Ravogli A, Arzilli F, OMBONI S, Giovannetti R, Mutti E, Salvetti A, Mancia G. Lack of effect of percutaneous transluminal renal angioplasty on nocturnal hypotension in renovascular hypertensive patients. J Hypertens 1996;1:53-6.
49 Parati G, Frattola A, OMBONI S, Mancia G, Di Rienzo M. Analysis of heart rate and blood pressure variability in the assessment of autonomic regulation in arterial hypertension. Clin Sci (Lond) 1996;91 Suppl:129-32.
50 Mancia G, Parati G, OMBONI S, Ravogli A, Villani A, Santucciu C, Ulian L. Ambulatory blood pressure monitoring in the ELSA study. European Lacidipine Study on Atherosclerosis. Blood Press Suppl 1996;4:36-8.
51 Mancia G, OMBONI S. Ambulatory blood pressure, blood pressure variability and antihypertensive treatment. Clin Exp Hypertens. 1996;3-4:449-62.
52 Mancia G, OMBONI S, Parati G. Lessons to be learned from 24-hour ambulatory blood pressure monitoring. Kidney Int Suppl 1996;55:S63-8.
53 Parati G, OMBONI S, Mancia G. Difference between office and ambulatory blood pressure and response to antihypertensive treatment. J Hypertens. 1996;6:791-7.
54 OMBONI S, Parati G, Di Rienzo M, Wieling W, Mancia G. Blood pressure and heart rate variability in autonomic disorders:a critical review. Clin Auton Res 1996;3:171-82.
55 Mancia G, Gamba PL, OMBONI S, Paleari F, Parati G, Sega R, Zanchetti A. Ambulatory blood pressure monitoring. J Hypertens Suppl 1996;2:S61-6;discussion S66-8.
56 OMBONI S, Parati G, Groppelli A, Ulian L, Mancia G. Performance of the AM-5600 blood pressure monitor:comparison with ambulatory intra-arterial pressure. J Appl Physiol 1997;2:698-703.
57 Mancia G, OMBONI S, Parati G. Assessment of antihypertensive treatment by ambulatory blood pressure. J Hypertens Suppl 1997;2:S43-50.
58 Mancia G, OMBONI S, Grassi G. Combination treatment in hypertension:the VeraTran Study. Am J Hypertens 1997;7 Pt 2:153S-158S.
59 Zanchetti A, OMBONI S, Di Biagio C. Candesartan cilexetil and enalapril are of equivalent efficacy in patients with mild to moderate hypertension. J Hum Hypertens 1997;2:S57-9.
60 Baccelli G, Reggiani P, Mattioli A, Corbellini E, Garducci S, Catalano M, OMBONI S. Hemodynamic changes in the lower limbs during treadmill walking in normal subjects and in patients with arteriosclerosis obliterans. Angiology 1997;9:795-803.
61 Santucciu C, Parati G, Ulian L, OMBONI S, Mancia G. [The difference between clinical ambulatory measured blood pressure and daily monitored pressure does not reflect the "white coat effect"]. Cardiologia 1997;10:1067-9.
62 Parati G, OMBONI S, Staessen J, Thijs L, Fagard R, Ulian L, Mancia G. Limitations of the difference between clinic and daytime blood pressure as a surrogate measure of the 'white-coat' effect. Syst-Eur investigators. J Hypertens 1998;1:23-9.
63 Mancia G, OMBONI S, Zanchetti A. Clinical advantages of lipophilic dihydropyridines. Blood Press Suppl. 1998;2:23-6.
64 Parati G, Ulian L, Santucciu C, OMBONI S, Mancia G. Difference between clinic and daytime blood pressure is not a measure of the white coat effect. Hypertension 1998;5:1185-9.
65 OMBONI S, Parati G, Palatini P, Vanasia A, Muiesan ML, Cuspidi C, Mancia G. Reproducibility and clinical value of nocturnal hypotension:prospective evidence from the SAMPLE study. Study on Ambulatory Monitoring of Pressure and Lisinopril Evaluation. J Hypertens 1998;6:733-8.

OMBONI S, Parati G, Mancia G. The trough:peak ratio and the smoothness index in the evaluation of control of 24 h blood pressure by treatment in hypertension. Blood Press Monit 1998;3:201-204.
67 OMBONI S, Parati G, Castiglioni P, Di Rienzo M, Imholz BP, Langewouters GJ, Wesseling KH, Mancia G. Estimation of blood pressure variability from 24-hour ambulatory finger blood pressure. Hypertension 1998;1:52-8.
68 OMBONI S, Fogari R, Palatini P, Rappelli A, Mancia G. Reproducibility and clinical value of the trough-to-peak ratio of the antihypertensive effect:evidence from the sample study. Hypertension 1998;3:424-9.
69 Mancia G, Cattaneo BM, OMBONI S, Grassi G. Clinical benefits of a consistent reduction in blood pressure. J Hypertens Suppl 1998;6:S35-9.
70 Parati G, OMBONI S, Rizzoni D, Agabiti-Rosei E, Mancia G. The smoothness index:a new, reproducible and clinically relevant measure of the homogeneity of the blood pressure reduction with treatment for hypertension. J Hypertens 1998;11:1685-91.
71 OMBONI S, Zanchetti A. Antihypertensive efficacy of lercanidipine at 2.5, 5 and 10 mg in mild to moderate essential hypertensives assessed by clinic and ambulatory blood pressure measurements. Multicenter Study Investigators. J Hypertens 1998;12 Pt 1:1831-8.
72 Mancia G, Parati G, OMBONI S, Ulian L, Zanchetti A. Ambulatory blood pressure monitoring. Clin Exp Hypertens 1999;5-6:703-15.
73 Castiglioni P, Parati G, OMBONI S, Mancia G, Imholz BP, Wesseling KH, Di Rienzo M. Broad-band spectral analysis of 24 h continuous finger blood pressure:comparison with intra-arterial recordings. Clin Sci (Lond) 1999;2:129-39.
74 OMBONI S, Parati G, Mancia G. [Monitoring of blood pressure for 24 hours:historical, technical, and methodological features]. Cardiologia 1999;1(Pt 2):997-1000.
75 Parati G, OMBONI S, Mancia G. [Trough-peak ratio and the smoothness index in the assessment of duration and homogeneity of 24-hour antihypertensive effect]. Cardiologia 1999;1(Pt 1):345-8.
76 Mancia G, OMBONI S, Parati G. The importance of blood pressure variability in hypertension. Blood Press Monit 2000;1:S9-S15.
77 Mancia G, OMBONI S, Agabiti-Rosei E, Casati R, Fogari R, Leonetti G, Montemurro G, Nami R, Pessina AC, Pirrelli A, Zanchetti A. Antihypertensive efficacy of manidipine and enalapril in hypertensive diabetic patients. J Cardiovasc Pharmacol 2000;6:926-31.
78 OMBONI S, Fogari R, Mancia G. A smooth blood pressure control is obtained over 24 h by delapril in mild to moderate essential hypertensives. Blood Press 2001;3:170-5.
79 Zanchetti A, OMBONI S. Comparison of candesartan versus enalapril in essential hypertension. Italian Candesartan Study Group. Am J Hypertens 2001;2:129-34.
80 Parati G, OMBONI S, Villani A, Glavina F, Castiglioni P, Di Rienzo M, Mancia G. Reproducibility of beat-by-beat blood pressure and heart rate variability. Blood Press Monit 2001;4:217-20.
81 Mancia G, OMBONI S, Parati G, Clement DL, Haley WE, Rahman SN, Hoogma RP. Twenty-four hour ambulatory blood pressure in the Hypertension Optimal Treatment (HOT) study. J Hypertens 2001;10:1755-63.
82 Zanchetti A, OMBONI S, La Commare P, De Cesaris R, Palatini P. Efficacy, tolerability, and impact on quality of life of long-term treatment with manidipine or amlodipine in patients with essential hypertension. J Cardiovasc Pharmacol 2001;4:642-50.
83 Mancia G, Parati G, Hennig M, Flatau B, OMBONI S, Glavina F, Costa B, Scherz R, Bond G, Zanchetti A;ELSA Investigators. Relation between blood pressure variability and carotid artery damage in hypertension:baseline data from the European Lacidipine Study on Atherosclerosis (ELSA). J Hypertens 2001;11:1981-9.
84 OMBONI S, Smit AA, van Lieshout JJ, Settels JJ, Langewouters GJ, Wieling W. Mechanisms underlying the impairment in orthostatic tolerance after nocturnal recumbency in patients with autonomic failure. Clin Sci (Lond) 2001;6:609-18.
85 Antonicelli R, OMBONI S, Giovanni DC, Ansuini R, Mori A, Gesuita R, Parati G, Paciaroni E. Smooth blood pressure control obtained with extended-release felodipine in elderly patients with hypertension: evaluation by 24-hour ambulatory blood pressure monitoring. Drugs Aging 2002;7:541-51.
86 Porcellati C, OMBONI S. Switching from ACE inhibitors, beta-blockers, calcium antagonists or diuretics to candesartan improves efficacy and tolerability. Blood Press 2002;5:310-9.
87 Mancia G, OMBONI S, Parati G;Investigators of the INSIGHT ABPM substudy. Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT). J Hypertens 2002;3:545-53.
88 Taddei S, OMBONI S, Ghiadoni L, Caiazza A, Fogari R, Innocenti P, Porcellati C, Giovannetti R, Corradi L, Mancia G, Salvetti A. Combination of lisinopril and nifedipine GITS increases blood pressure control compared with single drugs in essential hypertensive patients. J Cardiovasc Pharmacol 2003;4:579-85.
89 Mancia G, OMBONI S;CARDIO (CAndesaRtan combined with DIuretic in hypertensiOn) Study Group. Candesartan plus hydrochlorothiazide fixed combination vs previous monotherapy plus diuretic in poorly controlled essential hypertensive patients. Blood Press Suppl 2004;2:11-7.
90 Malacco E, Piazza S, OMBONI S;on behalf of the Zofenopril Study Group. Zofenopril versus Lisinopril in the Treatment of Essential Hypertension in Elderly Patients: A Randomised, Double-Blind, Multicentre Study. Clin Drug Investig 2005;3:175-182.
91 Mancia G, Parati G, Bilo G, Maronati A, OMBONI S, Baurecht H, Hennig M, Zanchetti A. Assessment of long-term antihypertensive treatment by clinic and ambulatory blood pressure:data from the European Lacidipine Study on Atherosclerosis. J Hypertens 2007;5:1087-94.
92 Orzalesi N, Rossetti L, OMBONI S;OPTIME Study Group (Osservatorio sulla Patologia glaucomatosa, Indagine Medico Epidemiologica);CONPROSO (Collegio Nazionale dei Professori Ordinari di Scienze Oftalmologiche). Vascular risk factors in glaucoma:the results of a national survey. Graefes Arch Clin Exp Ophthalmol 2007;6:795-802.
93 Pini C, Pastori M, Baccheschi J, OMBONI S, Parati G;European Society of Hypertension. Validation of the Artsana CSI 610 automated blood pressure monitor in adults according to the International Protocol of the European Society of Hypertension. Blood Press Monit 2007;3:179-84.
94 Bussone G, Tullo V, d'Onofrio F, Petretta V, Curone M, Frediani F, Tonini C, OMBONI S. Frovatriptan for the prevention of postdural puncture headache. Cephalalgia 2007;7:809-13.
95 OMBONI S, Riva I, Giglio A, Caldara G, Groppelli A, Parati G. Validation of the Omron M5-I, R5-I and HEM-907 automated blood pressure monitors in elderly individuals according to the International Protocol of the European Society of Hypertension. Blood Press Monit 2007;4:233-42.

96. Malacco E, OMBONI S. Antihypertensive efficacy of zofenopril plus hydrochlorothiazide fixed combination for treatment in metabolic syndrome. Adv Ther 2007;5:1006-15.
97 Pecori Giraldi F, Toja PM, De Martin M, Maronati A, Scacchi M, OMBONI S,Cavagnini F, Parati G. Circadian blood pressure profile in patients with active Cushing's disease and after long-term cure. Horm Metab Res 2007;12:908-14.
98 Pini C, Natalizi A, Gerosa PF, Frigerio M, OMBONI S, Parati G. Validation of the Artsana CS 410 automated blood pressure monitor in adults according to the International Protocol of the European Society of Hypertension. Blood Press Monit 2008;13:177-182.
99 OMBONI S, Costantini C, Pini C, Bulegato R, Manfellotto D, Rizzoni D, Palatini P, O'brien E, Parati G. PA.NET International Quality Certification Protocol for blood pressure monitors. Blood Press Monit 2008;13:285-289.
100 Parati G, OMBONI S, Palatini P, Rizzoni D, Bilo G, Valentini M, Agabiti-Rosei E, Mancia G. Italian Society of Hypertension Guidelines for Conventional and Automated Blood Pressure Measurement in the Office, at Home and Over 24 Hours. High Blood Pressure & Cardiovascular Prevention 2008;15:283-310.

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