Lawrence Lavery is a Professor in the Department of Plastic Surgery, as well as Director of Clinical Research in the Department of Plastic Surgery, at the University of Texas Southwestern Medical Center, Dallas, TX.  His research group has published 210 peer reviewed papers and has received extramural funding from the Veterans Administration, the National Institute of Health, the Agency for Healthcare Research and Quality, the American Diabetes Association, and the American College of Foot and Ankle Surgeons. 

Research Interest: Diabetes, Ulcers, Infections, Neuropathy and Osteomyelities

Grants: Supporting with number of grants

List of Publications:
1.    Lavery LA, Oz OK, Bhavan K, Wukich DK.  Diabetic Foot Syndrom in the Twenty-First Century.  Clin Podiatr Med Surg. 2019 July; 3, 355-359.
2.    Kim, PJ, Attinger CE, Orgill D, Galiano RD, Steinberg JS, Evans KK, Lavery LA.  Complex Lower Extremity Wound in the Complex Host:  Results from a Multicenter Registry.  Plastic and Reconstructive Surgery-Global. 2019 Apr.  Epub ahead of print.
3.    Ahn J, Raspovic KM, Liu GT, Lavery LA, La Fontaine J, Nakonezny PA, Wukich, DK.  Lower Extremity Necrotizing Fasciitis in Diabetic and Nondiabetic Patients:  Mortality and Amputation.  Int J Low Extrem Wounds.  2019 Apr.  Epub ahead of print.  PMID: 30929530.
4.    Lavery LA, Bhavan K, Wukich DK.  Biofilm and diabetic foot ulcer healing:  all hat and no cattle.  Annals of Translational Medicine 2019 Mar.  Epub ahead of print.
5.    La Fontaine J, Crisologo PA, Lavery L.  Current concepts in curative surgery for diabetic forefoot ulcers.  The Foot 2019 Jan 10 (39) 37-44.  Epub ahead of print.
6.    Olson E, Mahar KM, Morgan L, Fillmore C, Holland C, Lavery L.  Randomized Phase I Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Topical Daprodustat in Healthy Volunteers and Patients with Diabetic Foot Ulcers.  Clin Pharmacol Drug Dev. 2019 Feb 5. Epub ahead of print.  PMID:  30720931.
7.    Liu JW, Ahn J, Raspovic KM, Liu GT, Nakonezny PA, Lavery LA, Wukich DK.  Increased Rates of Readmission, Reoperation, and Mortality Following Open Reduction and Internal Fixation of Ankle Fractures are Associated with Diabetes Mellitus. J Foot Ankle Surg. 2019 Feb 11. Epub ahead of print.
8.    Ryan EC, Ahn J, Wukich DK, Kim PJ, La Fontaine J, Lavery LA.  Diagnostic Utility of Erythrocyte Sedimentation Rate and C-Reactive Protein in Osteomyelitis of the Foot in Persons without Diabetes.  J Foot Ankle Surg. 2019 Jan 23.  Epub ahead of print.
9.    Ahn J, Raspovic KM, Liu GT, Lavery LA, La Fontaine J, Nakonezny PA, Wukich DK.  Rental Function as a Predictor of Early Transmetatarsal Amputation Failure.  Foot Ankle Spec. 2018 Dec 12.  Epub ahead of print.  PMID:  30537872.
10.    Lavery LA, Crisologo PA.  Non-invasive vascular screening test to diagnose peripheral vascular disease.  Ann Transl Med. 2018 Dec; 6(Suppl 2).  PMID:  30740429.
11.    Yavuz M, Ersen A, Hartos J, LAVERY LA, Wukich D, Hirschman G, Armstrong D, Quiben M, Adams L.  Temperature as a Causative factor in Diabetic Foot Ulceration:  A Call to Revisit Ulcer Pathomechanics.  J Am Podiatr Med Assoc. 2018 Nov 14. (Epub ahead of print).  PMID:  30427732.
12.    Niederauer MQ, Michalek JE, Liu Q, Papas KK, LAVERY LA, Armstrong DG.  Continuous diffusion of oxygen improves diabetic foot ulcer healing when compared with a placebo control:  a randomized, double-blind, multicenter study.  J Wound Care.  2018 Sep 1;27(Sup9): S30-S45. PMID: 30207844.
13.    LAVERY, LA, Fulmer J, Shebetka KAS, Regulski M, Vayer, D, Fried D, Kashefsky H, Owings TM, Nadarajah J, Phelan DHK.  Open-label Extension Phase of a Chronic Diabetic Foot Ulcer Multicenter, Controlled, Ramdomised Clinical Trial Using Cryopreserved Placental Membrance.  Wounds Epub 2018 June.  PMID:  30256747.
14.    Raspovic KM, Wukich DK, Naiman DQ, LAVERY LA, Kirsner RS, Kim PJ, Steinberg JS, Attinger CE, Danilkovitch A.  Effectiveness of viable cryopreserved placental membranes for management of diabetic foot ulcers in a real world setting.  Wound Repair Regen, 2018 Mar; 26(2): 213-220.  PMID:  29683538.
15.    Ahn J, Del Core MA, Wukich DK, Liu GT, Lalli T, VanPelt MD, La Fontaine J, Lavery LA, Raspovic KM.  Scoring mental health quality of life with the SF-36 in patients with and without diabetes foot complications.  Int J Low Extrem Wounds.  2018 Mar.  PMID:  29546783.
16.    LAVERY LA, Lavery DC, Hunt NA, La Fontaine J, Lavery RD.  Does the start of dialysis initiate a period of increased risk of ulceration or amputation?  J Am Podiatr Med Assoc.  2018 Jan; 108-(1):1-5.  PMID:  29547031.
17.    Van Asten SAV, Mithani M, Peters EIG, La Fontaine J, Kim PJ, Lavery LA.  Complications during the treatment of diabetic foot osteomyelitis.  Diabetes Res Clin Pract. 2018 Jan;135:58-64. PMID: 28951333. 
18.    Crisologo PA, Lavery LA.  Remote home monitoring to identify and prevent diabetic foot ulceration.  Ann Transi Med.  2017 Nov;5(21):430.  PMID:  29201882.
19.    Lavery LA, Ryan EC.  Does Continuous Diffusion of Oxygen Improve Diabetic Foot Ulcer Healing?  J Diabetes Sci Technol. 2017 Sep; 11(5):892-893.  PMID: 28728437.
20.    Sanniec K, Nguyen T, van Asten S, La Fontaine J, Lavery LA.  Split-Thickness Skin Grafts to the Foot and Ankle of Diabetic Patients.  J Am Podiatr Med Assoc.  2017 Sep; 107(5):365-368.  PMID:  29077498.

Research Interest:

1. Obesity and metabolic diseases
2. Effect of sport in obesity and cardio-metabolic disturbances
3. Role of environmental pollutant in cardio-metabolic diseases

List of Publications:

1.    Della Guardia L, Shin AC. The role of adipose tissue dysfunction in PM2.5-induced vascular pathology. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H971-H972. doi: 10.1152/ajpheart.00156.2022
2.    De Nardi M, Bisio A, Della Guardia L, Facheris C, Faelli E, La Torre A, Luzi L, Ruggeri P, Codella R. Partial-Body Cryostimulation Increases Resting Energy Expenditure in Lean and Obese Women. Int J Environ Res Public Health. 2021 Apr 14;18(8):4127. doi: 10.3390/ijerph18084127.
3.    Della Guardia L, Shin AC. White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure. J Mol Med (Berl). 2022 May;100(5):665-676. doi: 10.1007/s00109-022-02183-6. Epub 2022 Mar 14
4.    Della Guardia L, Codella R. Exercise tolls the bell for key mediators of low-grade inflammation in dysmetabolic conditions. Cytokine Growth Factor Rev. 2021 Dec;62:83-93. doi: 10.1016/j.cytogfr.2021.09.003.
5.    Codella R, Della Guardia L, Terruzzi I, Solini A, Folli F, Varoni EM, Carrassi A, Luzi L. Physical activity as a proxy to ameliorate inflammation in patients with type 2 diabetes and periodontal disease at high cardiovascular risk. Nutr Metab Cardiovasc Dis. 2021 Jul 22;31(8):2199-2209. doi: 10.1016/j.numecd.2021.04.022.
6.    Della Guardia L, Codella R. Airways to heaven: Caution needed when exercising during COVID-19. Med Hypotheses. 2021 Mar;148:110522. doi: 10.1016/j.mehy.2021.110522.
7.    Moreno C, Della Guardia L, Shnyder V et al. iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signal. Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.
8.    Maurizi G, Babini L, Della Gaurdia L. Potential role of microRNAs in the regulation of adipocytes liposecretion and adipose tissue physiology. Journal of Cellular Physiology.
9.    Della Guardia L, Thomas MA, Cena H. Insulin Sensitivity and Glucose Homeostasis Can Be Influenced by Metabolic Acid Load. Nutrients 2018, 10, 618; doi:10.3390/nu10050618
10.    Maurizi G, Petäistö T, Maurizi A, Della Guardia L. Key-genes regulating the liposecretion process of mature adipocytes. J Cell Physiol. 2018 May;233(5):3784-3793.
11.    Manuelli M, Della Guardia L, Cena H. Enriching Diet with n-3 PUFAs to Help Prevent Cardiovascular Diseases in Healthy Adults: Results from Clinical Trials. Int J Mol Sci. 2017 Jul 18;18(7)
12.    Maurizi G, Della Guardia L, Maurizi A, Poloni A. Adipocytes properties and crosstalk with immune system in obesity-related inflammation. J Cell Physiol. 2018;233:88–97.
13.    Della Guardia L, Roggi C, Cena H. Diet-induced acidosis and alkali supplementation. Int J Food Sci Nutr. 2016 Jun 24:1-8.
14.    Della Guardia L, Cavallaro M, Cena H. The risks of self-made diets: the case of an amateur bodybuilder. J Int Soc Sports Nutr. 2015 Apr 1;12:16.
15.    Della Guardia L. Guarene M. Calcaterra V Vandoni M Cena H. Effects of a multidisciplinary intervention on childhood obesity". 2nd N&G conference Barcelona. 30 Jen-2 Feb 2014.
16.    Guarene M. Calcaterra V, De Giuseppe R, Della Guardia L, et al. Lifestyle, nutritional Knowledge and fears of a group of adolescents suffering from type 1 diabetes. Clin Nutr 2014 Sep (Supp); 33:S174

Research Interest: Molecular Pharmacology, Chinese Medicines and Diabetes Mellitus, Effects and Mechanism of Natural Products on Cardio-Cerebrovascular Disease.

Research Interest: Liver Cirrhosis, Gastrointestinal Diseases, Liver, Hepatitis, Chronic Hepatitis C, Cirrhosis, Bacteria, Virulence Factors, Cells

China Diabetes Impact Study is funded by IDF and technically supported by Division of Diabetes Translation of CDC. It is a follow-up study of China National Diabetes and Metabolic Disorder Study. A total of 12 study sites participated in the China Diabetes Impact Study. I am the national program coordinator and the investigator of Beijing study site. All study participants with DM, NDM and IGR were interviewed and collected information about their health care service use, medical expenditure, etc. 

Research Interest: Diabetes; Metabolic Syndrome; Osteoporosis

Research Interest: Multicenter Prospective Observational CREST Study (U.Penn, Vanderbilt, and University Hospitals Case Medical Center) with Dr. James Fang, Evaluating Cardiotoxicity of Sunitinib in Metastatic Renal Cell Carcinoma Using Tonometry Data

Research Interest: Internal Medicine and Cardiology

Dr. Ahed J Alkhatib is currently working as a researcher in Department of Forensic Science and Toxicology, Jordan University of Sciences and Technology, Jordon from 2011 to till date. He completed his PhD in Campbell University, medical technology, North Carolina, USA from 2008 to 2011. Dr. Ahed J Alkhatib is a member of council of nutritional and environmental disease (CONEM). He is conducting research that generates new theories. Dr. Ahed J Alkhatib has done 116 Publications. He is establishing new science (molecular sociology).

Research Interest:  Neurology; Pharmacology; diabetes; Philosophy of science; Tumor research; Behavioral biology; Emergency medicine

List of Publications:

1-    Amro Saleem Falah Alamaren and Ahed J. Alkhatib (2019). The Relationship Between Financial Stability and Insurance. International Business Management, 13: 130-133.

2-    Ahed J Alkhatib (2019). Expression and Releasing of Cell Cycle Proteins by Candida albicans into Surrounding Tissue: New Perspectives of the Relationship between Microbes and Host. EC Microbiology, 15 (3): 168-171.

3-     Samirah Fahad A, Ahed Alkhatib (2019). The Assessment of Intervention Programs for Autism Including Children and their Parents. Am J Biomed Sci & Res., 1(6): 236-238. AJBSR.MS.ID.000553.

4-    Kawther Faisal Amawi, Inas Saleh Al-Mazari, Ali Alsarhan, Hamza Qasim Mohammad Alhamad, Ahed J. Alkhatib (2019). Diabetes upregulates the expression of HSP90 and downregulates HSP70 in the liver of diabetic rats. Comparative Clinical Pathology, 28 (2): 473-478.

5-    Ahed J. Alkhatib (2019). The Progression of a Disease Depends on Downregulation of Heat Shock Protein 70 (HSP70) And Upregulation of Inducible Nitric Oxide Synthase (iNOS): A New Medical Hypothesis. Biomed Discoveries: 1-3, DOI: 10.29011/ BMDC-103. 100003.

6-    Mohammad A. Bani-Ahmad, Suleimman A. Al-Sweedan, Mohammad A. Al-Asseiri, Ahed J. Alkhatib (2018). A Proposed Kinetic Model for the Diagnostic and Prognostic Value of WT1 and p53 in Acute Myeloid Leukemia. Clinical laboratory, 64 (3):357-363. doi: 10.7754/Clin.Lab.2017.170915.

7-    Ahed J Alkhatib, Ilham Ahed Alkhatib (2018). Metformin and Urtica pilulifera: Comparable Effects and Similar Actions in Diabetes. Int J Pharm,  8(3): 1-2.

8-    Ahed J Alkhatib (2018). White Matter Ageing: Etiology and Prognosis. Appl Cell Biol, 6 (2), 14-17.
 
9-    Khaled Z. Alawneh, Liqaa A. Raffee, Haytham A. Al Ewaidat and Ahed J. Alkhatib (2018).. The Impact of Exposure to Medical Radiation on Lead (Pb+2) and Thyroid Function Test. Research Journal of Medical Sciences, 12: 31-34.

10-    Hani A. Masaadeh, Ali Alrifai, Ahed J Alkhatib and Mamdoh Meqdam (2018). Molecular Epidemiology of Extended-Spectrum β-Lactamase-ProducingK. pneumoniae in Northern Jordan. Research Journal of Medical Sciences, 12: 63-69.

11-    Ahed J Alkhatib (2018). Does Epstein - Barr Virus Cross Talks with Sex Hormone Receptors on Lymphoid Cells Differently to Produce Lymphoma? Int J Pharm, 8(1): 56-57.

12-    Ahed J Alkhatib (2018). Non-classical Roles of Microbes.  PSM Microbiol., 3(2): 62-63.

13-    Sani S Bala, Ahed J Alkhatib, SS Bashir, Abdulhadi M (2018). Photocatalytic Degradation of Indigo Carmine in Aqueous Solutions by the Antibacterial Agent Pefloxacin and UVA. Biomed J Sci&Tech Res 5(5), DOI: 10.26717/ BJSTR.2018.05.001275.

14-    Sonia Cherian, Ahed J Alkhatib, Megha Aggarwal (2018). Relationship between organizational commitment and job satisfaction of nurses in Dubai hospital. Journal of Advances in Social Science and Humanities, 4(1): 36373-36400.

15-    Amro Saleem Falah Alamaren, Ahed J Alkhatib (2018). Financial Aspects Associated with Overuse of Health Resources. Biomed J Sci&Tech Res 7(1). BJSTR. MS.ID.001444. DOI: 10.26717/ BJSTR.2018.07.001444.

16-    Ahed J Alkhatib, Khalid Alzaailay (2018). The Appropriate Use of Activated Charcoal in Pharmaceutical and Toxicological Approaches. Biomed J Sci & Tech Res, 5 (2),

17-    Ahed J Alkatib (2017). Diabetes and diabetic neuropathies are independent events: a new medical hypothesis. Ind Res J Pharm & Sci, 4 (3): 1064-1067.


18-    Ahed J Alkhatib (2019). The Use of Crude Extract of Alhagi graecorum and Urtica pilulifera in the Treatment of Chronic Inflammation of Seminal Fluid: A Case Study. Open Acc J Comp & Alt Med 1(4): 62-64.

19-    Ahed J Alkhatib (2019). New Insights to Diabetes: Is Diabetes a Metabolic Disorder or a Neurological Disease? International Journal of Diabetes & Metabolic Disorders, 4 (1).

20-    Ahed J Alkhatib (2019). White Matter: Structural and Functional Roles in Health and Disease. PSM Biological Research, 4 (1): 17-19.

21-    Ahed J Alkhatib (2018). The role of natural antioxidants in declining memory defects in Alzheimer’s disease. J Spine Neurosurg, 7, DOI: 10.4172/2325-9701-C7-030.

22-    Alkhatib, A. J., (2018). Crude Extract of Potato Ameliorates Clinical Impacts of Infection with Helicobacter pylori: Case Study. PSM Microbiol. 3(2): 64-66.

23-    Ahed J Alkhatib (2018). It is time to change the concept of herbal use to molecular food. Ind Res J Pharm & Sci, 5 (4): 1648.

24-    Ahed J Alkhatib, Ilham Ahed Alkhatib, Kawther Faisal Amawi, Ali Alsarhan, Suha K Ababneh (2018). Sickle cell disease: molecular and pathophysiological features. Ind Res J Pharm & Sci, 5 (1), 1251-1259.

25-    Ahed J Alkhatib, Nayef Alzame (2018). Neurotoxicity and criminal behavior. Indian research journal of pharmacy and science, 5 (2): DOI: 1234-1238. 10.26717/BJSTR.2018.05.001170.

26-    Ahed J Alkhatib (2018). WHITE MATTER ASSOCIATED DISEASES.  Indian research journal of pharmacy and science, 5 (2): 1416-1419.

27-    Ahed J Alkhatib, Sani S. Bala, S.S. Bashir, Abdulhadi M (2018). Chemical and pharmaceutical properties of pefloxacin: a review. Indian research journal of pharmacy and science, 5 (2): 1427-1431.

28-    Mohamad M J Mohamad, Mustafa Al-Shehabat, Issa Ahmad AlShehabat, Ahed J Alkhatib (2018). The variations in altitude predict angiotensin ii and blood pressure variables in Jordan. Indian research journal of pharmacy and science, 5 (2): 1449-1455.


29-    Ahed J Alkhatib (2018). New Perspectives of Autoimmunity Diseases and Microbiome: Etiology and Treatment. Acta Scientific Pharmaceutical Sciences, 2(10): 12-14.

30-    Ahed J Alkhatib (2017). White Matter and Disease: Does Brain have a Role in Initiating Diseases. Brain Disorders & Therapy, 6: e124. doi: 10.4172/2168-975X.1000e124.

Research Interest: Blood Brain Barrier; Neurovascular Pharmacokinetics; Stroke; Ischemia; Neurodegneration; Neuroprotection; Neuropharmacology; Nutrient and Ion Transporters; Diabetes

Research Interest: Metabolomics Studies, Particularly on the Fetal-Neonatal Nutrition and Prevention of Chronic Diseases in Adults such as Obesity, Diabetes and Metabolic Syndrome.

Research Interest: Dietetics Applied to Bariatric Ssurgery; Clinical Impact of Bariatric Surgery on Patient’s Body Composition (Fat Mass and Fat-Free Mass) and Resting Metabolic Rate; Pre- and Post-Operative Treatment of Micronutrient Deficiencies in Patients that Underwent Bariatric Surgery.

Research Interest: Epidemiology, pathogenesis, diagnosis and treatment of fatty liver (metabolic and viral); genetic determinants of fatty liver; metabolic syndrome; insulin resistance; association between fatty liver, metabolic syndrome, diabetes and cardiovascular diseases;  liver ultrasonography.

Research Interest: Has Experience in Physical Therapy, with an Emphasis on Cardiopulmonary Physical Therapy, Acting on the Following Topics: Health Promotion, Cardiac Rehabilitation, Exercise Prescription for People with Special Needs, Assessment of Autonomic Function, Analysis of Biological Signals, Cardiorespiratory Physiotherapy in Morbid Obesity and Physical Therapy in Intensive Care. 

Research Interest: He has Vast Experience in Characterization of New Chemical Entities (NCE’S) for Early Stage Dosage form Development, Preparation of Nano Particles, Spray Dried Powders, Solubility Screening, Bio-Availability Enhancement, Granulation and Fluid Bed Drying, Compression Using Rotary Tablet Press, Coating, Stability Studies and Tech Transfer Etc.