Research Interest: A Biomedical Researcher with a Focus on Neurobehavioral, Metabolic and Endocrine Disorders.

Research Interest: My Research has Focused on Understanding the BBB, Changes that Occur in the Blood-Tumor-Barrier (BTB), and Drug Uptake Therein. To this End, I Have Worked and Gained Significant Amount of Knowledge on Factors Influencing Anticancer Delivery and Activity in Brain aBrain Metastases Developed from Breast Cancer in Mouse Models. These Include: (1) How BBB is Altered in Mouse Models of Brain Metastases of Breast Cancer. (2) Pharmacokinetic-Pharmacodynamic Relationship of Anticancer Drugs in Brain Metastases. (3) in Vitro- In Vivo Correlations (IVIVC) to Predict Optimum Therapeutic Concentrations for Treatment of Brain Metastases. (4) Improving Targeted Anticancer Drug Delivery to Brain Tumors by Inhibiting Efflux Transporters and Piggy Backing Drugs to Substrates of Influx Transporters at the BBB.

Research Interest: Deep Specialization in Research Involve; Obesity and Associated Disorder, Its Mechanism and Treatment. Metabolic Syndrome-Food Additives and Its Effect on the Bodyorgans. Also the Biochemical, Oxidative Stress and Advanced Biomarkers in Health and Diseases. Recently Involved in Nanomedical Materials as Antioxidant for Health Maintainance.

Research Interest:

1. Obesity and metabolic diseases
2. Effect of sport in obesity and cardio-metabolic disturbances
3. Role of environmental pollutant in cardio-metabolic diseases

List of Publications:

1.    Della Guardia L, Shin AC. The role of adipose tissue dysfunction in PM2.5-induced vascular pathology. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H971-H972. doi: 10.1152/ajpheart.00156.2022
2.    De Nardi M, Bisio A, Della Guardia L, Facheris C, Faelli E, La Torre A, Luzi L, Ruggeri P, Codella R. Partial-Body Cryostimulation Increases Resting Energy Expenditure in Lean and Obese Women. Int J Environ Res Public Health. 2021 Apr 14;18(8):4127. doi: 10.3390/ijerph18084127.
3.    Della Guardia L, Shin AC. White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure. J Mol Med (Berl). 2022 May;100(5):665-676. doi: 10.1007/s00109-022-02183-6. Epub 2022 Mar 14
4.    Della Guardia L, Codella R. Exercise tolls the bell for key mediators of low-grade inflammation in dysmetabolic conditions. Cytokine Growth Factor Rev. 2021 Dec;62:83-93. doi: 10.1016/j.cytogfr.2021.09.003.
5.    Codella R, Della Guardia L, Terruzzi I, Solini A, Folli F, Varoni EM, Carrassi A, Luzi L. Physical activity as a proxy to ameliorate inflammation in patients with type 2 diabetes and periodontal disease at high cardiovascular risk. Nutr Metab Cardiovasc Dis. 2021 Jul 22;31(8):2199-2209. doi: 10.1016/j.numecd.2021.04.022.
6.    Della Guardia L, Codella R. Airways to heaven: Caution needed when exercising during COVID-19. Med Hypotheses. 2021 Mar;148:110522. doi: 10.1016/j.mehy.2021.110522.
7.    Moreno C, Della Guardia L, Shnyder V et al. iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signal. Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.
8.    Maurizi G, Babini L, Della Gaurdia L. Potential role of microRNAs in the regulation of adipocytes liposecretion and adipose tissue physiology. Journal of Cellular Physiology.
9.    Della Guardia L, Thomas MA, Cena H. Insulin Sensitivity and Glucose Homeostasis Can Be Influenced by Metabolic Acid Load. Nutrients 2018, 10, 618; doi:10.3390/nu10050618
10.    Maurizi G, Petäistö T, Maurizi A, Della Guardia L. Key-genes regulating the liposecretion process of mature adipocytes. J Cell Physiol. 2018 May;233(5):3784-3793.
11.    Manuelli M, Della Guardia L, Cena H. Enriching Diet with n-3 PUFAs to Help Prevent Cardiovascular Diseases in Healthy Adults: Results from Clinical Trials. Int J Mol Sci. 2017 Jul 18;18(7)
12.    Maurizi G, Della Guardia L, Maurizi A, Poloni A. Adipocytes properties and crosstalk with immune system in obesity-related inflammation. J Cell Physiol. 2018;233:88–97.
13.    Della Guardia L, Roggi C, Cena H. Diet-induced acidosis and alkali supplementation. Int J Food Sci Nutr. 2016 Jun 24:1-8.
14.    Della Guardia L, Cavallaro M, Cena H. The risks of self-made diets: the case of an amateur bodybuilder. J Int Soc Sports Nutr. 2015 Apr 1;12:16.
15.    Della Guardia L. Guarene M. Calcaterra V Vandoni M Cena H. Effects of a multidisciplinary intervention on childhood obesity". 2nd N&G conference Barcelona. 30 Jen-2 Feb 2014.
16.    Guarene M. Calcaterra V, De Giuseppe R, Della Guardia L, et al. Lifestyle, nutritional Knowledge and fears of a group of adolescents suffering from type 1 diabetes. Clin Nutr 2014 Sep (Supp); 33:S174

Research Interest: He Also Conducted Basic Research in Regard to the Investigation of the Role of Immunological Aspects in Kidney Diseases Including Nephritic Syndrome and Diabetic Nephropathy.

Research Interest: Nutrition, Weight management, Obesity Evaluation, Behavior Change Interventions, Critical Thinking, Health Disparity, Curriculum and Program Development, Type 2 Diabetes

Research Interest: Kidney transplantation, glomerular disease and pathological basics of the diseases

Research Interest: Obesity, Chronic Hronic Inflammation, Inflammatory Disease, Cancer

Research Interest: Has Experience in Physical Therapy, with an Emphasis on Cardiopulmonary Physical Therapy, Acting on the Following Topics: Health Promotion, Cardiac Rehabilitation, Exercise Prescription for People with Special Needs, Assessment of Autonomic Function, Analysis of Biological Signals, Cardiorespiratory Physiotherapy in Morbid Obesity and Physical Therapy in Intensive Care. 

Dr. Ahed J Alkhatib is currently working as a researcher in Department of Forensic Science and Toxicology, Jordan University of Sciences and Technology, Jordon from 2011 to till date. He completed his PhD in Campbell University, medical technology, North Carolina, USA from 2008 to 2011. Dr. Ahed J Alkhatib is a member of council of nutritional and environmental disease (CONEM). He is conducting research that generates new theories. Dr. Ahed J Alkhatib has done 116 Publications. He is establishing new science (molecular sociology).

Research Interest:  Neurology; Pharmacology; diabetes; Philosophy of science; Tumor research; Behavioral biology; Emergency medicine

List of Publications:

1-    Amro Saleem Falah Alamaren and Ahed J. Alkhatib (2019). The Relationship Between Financial Stability and Insurance. International Business Management, 13: 130-133.

2-    Ahed J Alkhatib (2019). Expression and Releasing of Cell Cycle Proteins by Candida albicans into Surrounding Tissue: New Perspectives of the Relationship between Microbes and Host. EC Microbiology, 15 (3): 168-171.

3-     Samirah Fahad A, Ahed Alkhatib (2019). The Assessment of Intervention Programs for Autism Including Children and their Parents. Am J Biomed Sci & Res., 1(6): 236-238. AJBSR.MS.ID.000553.

4-    Kawther Faisal Amawi, Inas Saleh Al-Mazari, Ali Alsarhan, Hamza Qasim Mohammad Alhamad, Ahed J. Alkhatib (2019). Diabetes upregulates the expression of HSP90 and downregulates HSP70 in the liver of diabetic rats. Comparative Clinical Pathology, 28 (2): 473-478.

5-    Ahed J. Alkhatib (2019). The Progression of a Disease Depends on Downregulation of Heat Shock Protein 70 (HSP70) And Upregulation of Inducible Nitric Oxide Synthase (iNOS): A New Medical Hypothesis. Biomed Discoveries: 1-3, DOI: 10.29011/ BMDC-103. 100003.

6-    Mohammad A. Bani-Ahmad, Suleimman A. Al-Sweedan, Mohammad A. Al-Asseiri, Ahed J. Alkhatib (2018). A Proposed Kinetic Model for the Diagnostic and Prognostic Value of WT1 and p53 in Acute Myeloid Leukemia. Clinical laboratory, 64 (3):357-363. doi: 10.7754/Clin.Lab.2017.170915.

7-    Ahed J Alkhatib, Ilham Ahed Alkhatib (2018). Metformin and Urtica pilulifera: Comparable Effects and Similar Actions in Diabetes. Int J Pharm,  8(3): 1-2.

8-    Ahed J Alkhatib (2018). White Matter Ageing: Etiology and Prognosis. Appl Cell Biol, 6 (2), 14-17.
 
9-    Khaled Z. Alawneh, Liqaa A. Raffee, Haytham A. Al Ewaidat and Ahed J. Alkhatib (2018).. The Impact of Exposure to Medical Radiation on Lead (Pb+2) and Thyroid Function Test. Research Journal of Medical Sciences, 12: 31-34.

10-    Hani A. Masaadeh, Ali Alrifai, Ahed J Alkhatib and Mamdoh Meqdam (2018). Molecular Epidemiology of Extended-Spectrum β-Lactamase-ProducingK. pneumoniae in Northern Jordan. Research Journal of Medical Sciences, 12: 63-69.

11-    Ahed J Alkhatib (2018). Does Epstein - Barr Virus Cross Talks with Sex Hormone Receptors on Lymphoid Cells Differently to Produce Lymphoma? Int J Pharm, 8(1): 56-57.

12-    Ahed J Alkhatib (2018). Non-classical Roles of Microbes.  PSM Microbiol., 3(2): 62-63.

13-    Sani S Bala, Ahed J Alkhatib, SS Bashir, Abdulhadi M (2018). Photocatalytic Degradation of Indigo Carmine in Aqueous Solutions by the Antibacterial Agent Pefloxacin and UVA. Biomed J Sci&Tech Res 5(5), DOI: 10.26717/ BJSTR.2018.05.001275.

14-    Sonia Cherian, Ahed J Alkhatib, Megha Aggarwal (2018). Relationship between organizational commitment and job satisfaction of nurses in Dubai hospital. Journal of Advances in Social Science and Humanities, 4(1): 36373-36400.

15-    Amro Saleem Falah Alamaren, Ahed J Alkhatib (2018). Financial Aspects Associated with Overuse of Health Resources. Biomed J Sci&Tech Res 7(1). BJSTR. MS.ID.001444. DOI: 10.26717/ BJSTR.2018.07.001444.

16-    Ahed J Alkhatib, Khalid Alzaailay (2018). The Appropriate Use of Activated Charcoal in Pharmaceutical and Toxicological Approaches. Biomed J Sci & Tech Res, 5 (2),

17-    Ahed J Alkatib (2017). Diabetes and diabetic neuropathies are independent events: a new medical hypothesis. Ind Res J Pharm & Sci, 4 (3): 1064-1067.


18-    Ahed J Alkhatib (2019). The Use of Crude Extract of Alhagi graecorum and Urtica pilulifera in the Treatment of Chronic Inflammation of Seminal Fluid: A Case Study. Open Acc J Comp & Alt Med 1(4): 62-64.

19-    Ahed J Alkhatib (2019). New Insights to Diabetes: Is Diabetes a Metabolic Disorder or a Neurological Disease? International Journal of Diabetes & Metabolic Disorders, 4 (1).

20-    Ahed J Alkhatib (2019). White Matter: Structural and Functional Roles in Health and Disease. PSM Biological Research, 4 (1): 17-19.

21-    Ahed J Alkhatib (2018). The role of natural antioxidants in declining memory defects in Alzheimer’s disease. J Spine Neurosurg, 7, DOI: 10.4172/2325-9701-C7-030.

22-    Alkhatib, A. J., (2018). Crude Extract of Potato Ameliorates Clinical Impacts of Infection with Helicobacter pylori: Case Study. PSM Microbiol. 3(2): 64-66.

23-    Ahed J Alkhatib (2018). It is time to change the concept of herbal use to molecular food. Ind Res J Pharm & Sci, 5 (4): 1648.

24-    Ahed J Alkhatib, Ilham Ahed Alkhatib, Kawther Faisal Amawi, Ali Alsarhan, Suha K Ababneh (2018). Sickle cell disease: molecular and pathophysiological features. Ind Res J Pharm & Sci, 5 (1), 1251-1259.

25-    Ahed J Alkhatib, Nayef Alzame (2018). Neurotoxicity and criminal behavior. Indian research journal of pharmacy and science, 5 (2): DOI: 1234-1238. 10.26717/BJSTR.2018.05.001170.

26-    Ahed J Alkhatib (2018). WHITE MATTER ASSOCIATED DISEASES.  Indian research journal of pharmacy and science, 5 (2): 1416-1419.

27-    Ahed J Alkhatib, Sani S. Bala, S.S. Bashir, Abdulhadi M (2018). Chemical and pharmaceutical properties of pefloxacin: a review. Indian research journal of pharmacy and science, 5 (2): 1427-1431.

28-    Mohamad M J Mohamad, Mustafa Al-Shehabat, Issa Ahmad AlShehabat, Ahed J Alkhatib (2018). The variations in altitude predict angiotensin ii and blood pressure variables in Jordan. Indian research journal of pharmacy and science, 5 (2): 1449-1455.


29-    Ahed J Alkhatib (2018). New Perspectives of Autoimmunity Diseases and Microbiome: Etiology and Treatment. Acta Scientific Pharmaceutical Sciences, 2(10): 12-14.

30-    Ahed J Alkhatib (2017). White Matter and Disease: Does Brain have a Role in Initiating Diseases. Brain Disorders & Therapy, 6: e124. doi: 10.4172/2168-975X.1000e124.

Research Interest: Internal Medicine and Cardiology

Research Interest: He has Vast Experience in Characterization of New Chemical Entities (NCE’S) for Early Stage Dosage form Development, Preparation of Nano Particles, Spray Dried Powders, Solubility Screening, Bio-Availability Enhancement, Granulation and Fluid Bed Drying, Compression Using Rotary Tablet Press, Coating, Stability Studies and Tech Transfer Etc.

Research Interest: Dietetics Applied to Bariatric Ssurgery; Clinical Impact of Bariatric Surgery on Patient’s Body Composition (Fat Mass and Fat-Free Mass) and Resting Metabolic Rate; Pre- and Post-Operative Treatment of Micronutrient Deficiencies in Patients that Underwent Bariatric Surgery.

Dr. Mehta’s research program focuses on the role of innate immunity and inflammation in the development of cardiovascular and metabolic diseases. Using a trans-disciplinary approach that involves genetic epidemiology, translational medicine, and novel cardiovascular imaging approaches, Dr. Mehta and his team study how inflammation affects insulin resistance, the development of metabolic syndrome, and lipoprotein dysfunction, all of which are risk factors for atherosclerosis and subsequent cardiovascular disease (CVD).

Research Interest: Cardiovascular Disease, Electrophysiology, Pacemaker, ICD and CRT Therapy, Metabolic Syndrome, Bidirectional Effect of CVD and CKD