Research Interest: Immune-checkpoint proteins suppress
tumor-specific immune responses and hamper the efficacy of cancer
vaccine. My research in the past 7 years has been focused on
understanding how immune-checkpoint proteins regulate anti-tumor
immunity. My earlier work has identified a novel function of PD-1, an
established immune-checkpoint protein in regulating the differentiation
of tumor-induced adaptive Foxp3+ CD4+ regulatory T cells (PNAS, 2008).
My recent work has discovered VISTA, a novel immune-checkpoint protein
that critically regulates tumor-specific immunity (JEM, 2011). My
ongoing work focuses on understanding VISTA-mediated immune regulation
in, and designing novel combinatorial strategies that targets VISTA and
additional immune-checkpoint proteins such as CTLA-4 and PD-1 for cancer
immunotherapy
Indexing/Archiving
Editor-in-Chief
Michel BOURIN University of Nantes, France Archives of Depression and Anxiety
Wei Min HUANG Nanyang Technological University, Singapore Archive of Biomedical Science and Engineering
EXBRAYAT Jean-Marie Catholic University of Lyon, France Annals of Cytology and Pathology
Giulio Perrotta Marche Polytechnic University - School of Medicine and Surgery (UNIVPM, Ancona - Italy); Istituto per lo studio delle psicoterapie (ISP, Rome - Italy). , Italy Open Journal of Trauma
Thomas F. George University of Missouri - St. Louis, USA Open Journal of Analytical and Bioanalytical Chemistry
Giuseppe Murdaca University of Genoa, Italy Global Journal of Allergy
Osmar Antonio Centurion Asuncion National University, Paraguay Global Journal of Medical and Clinical Case Reports
Hermis Iatrou University of Athens, Greece Open Journal of Chemistry
Miklas Scholz Lund University, Sweden Annals of Environmental Science and Toxicology
Ray Marks Columbia University, USA Journal of Novel Physiotherapy and Physical Rehabilitation
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