Biography: Young and passionate graduate in molecular and cellular biology, researcher in the field of pharmacology and oncology, with great interest in the mechanisms of angiogenesis and development of the tumor microenvironment, pharmacological resistance.
Research Interest: Molecular and cellular biology, angiogenesis, tumor angiogenesis and microenvironment, oncology pharmacology, preclinical research, natural substances and nutraceuticals
Biography: Prof. Joan Lluís Vives
Corrons is Professor Emeritus at the University of Barcelona and an honorary
researcher at the Josep Carreras Institute for Leukaemia Research (IJC). He has
an extensive background in diagnosing rare anemias and studying the molecular
bases of red blood cell (RBC) enzymopathies, membranopathies, and
hemoglobinopathies.
Over
more than 30 years, he served as head of the Haematology Laboratory Department
(1976-1997) and head of the Red Blood Cell Pathology Unit (1998-2016). His research
has focused on the physiopathology of anemia, particularly the molecular and
genetic mechanisms of congenital anemias related to RBCs and erythropoietic
defects. He has been the principal investigator (PI) for over 35 research
projects, primarily on erythroenzymopathies like glucose-6-phosphate
dehydrogenase (G6PD) and pyruvate kinase (PK) deficiencies, hemoglobinopathies
such as sickle-cell disease (SCD) and thalassemia, and hereditary hemolytic
anemias (HHA) due to RBC membranopathies.
In 2002, Prof. Vives Corrons became the coordinator of the European Network for
Rare and Congenital Anaemias (ENERCA), co-financed by the European Commission
(EC) under its Public Health System (SANCO-Public Health). ENERCA aimed to
establish a pan-European network for the diagnosis, registry, and treatment of
rare anemias (RA) in Europe. Currently, he serves as chairman of the Scientific
Board of the Rare Anemias International Network (RAIN), supported by the
Thalassemia International Federation (TIF).
Research Interest: principal investigator
(PI) for over 35 research projects, primarily on erythroenzymopathies
like glucose-6-phosphate dehydrogenase (G6PD) and pyruvate kinase (PK)
deficiencies,
hemoglobinopathies such as
sickle-cell disease (SCD) and thalassemia, and hereditary hemolytic
anemias (HHA) due to RBC membranopathies
Medical
education in Bern and Geneva, MD 1978. PhD 1984 and FMH in pathology 1988 in
Basel.
Positions
held: 1974 Immunology University of Bern, 1979 Pharmacology, Sandoz Pharma
Basel, 1991 University of Zurich, Pharmacology-Toxicology, Immunology
University Cape Town, RSA. Since 2001 Director of research, CNRS Immunology,
Orleans, France with active research, and advisor of several pharmaceutical
companies. Founder of IBR Inc, Artimmune SAS and Phenotec AG.
Research Interests:
Mechanisms of inflammation, especially respiratory inflammation, fibrosis,
emphysema and COPD, but also in skin, hepatic, intestinal, renal and CNS
inflammation. Cell death, innate immune danger sensing and cGAS/STING, ROS and
Inflammasome activation in models of human inflammatory diseases and tumor
development, role of microbiome, metabolome, neuroinflammation/degeneration and
ageing.
Role of TNF and IL-1
members, in cell death and IL-33 and T2 / T17 polarization and differentiation.
PB drug candidate
Stable butyrate to treat chronic lung inflammatory disease
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