Innovative Approach to Upper Limb Salvage: Ozone Therapy and Surgical Lavage in Action. A Case Report

M Mascia, M Mazzocchi*, D Passador, E Pariani, E Scalamandrè, G Forini, F Cuzzocrea and A Locatelli

Upper limb injuries after major trauma often result in severe damage to bones, vessels, nerves, and soft tissues, leading to critical challenges in management. The decision between limb salvage and amputation is complex, especially in the context of a "mangled" extremity, which significantly affects functional, psychological, and social well-being. This case report details the innovative use of oxygen-ozone therapy combined with surgical management in a 34-year-old male who suffered a catastrophic injury to the left upper limb after a car crash. The patient presented extensive soft tissue loss, multiple open fractures, and severe infection leading to septic shock and multiorgan failure. Initial treatment included surgical lavage, Vacuum-Assisted Closure (VAC) therapy, and targeted antibiotics. Given the critical condition and the high risk of limb amputation, daily oxygen-ozone therapy was introduced through major autohemotherapy. The treatment resulted in rapid clinical improvement, including hemodynamic stabilization, reduction of inflammation, and enhanced wound healing. Definitive osteosynthesis and flap grafting were performed successfully 42 days post-admission. At the one-year follow-up, the patient demonstrated preserved hand and wrist function with some limitations in flexion and pronosupination. This case highlights the potential of oxygen-ozone therapy as an adjunct in limb salvage, offering a promising alternative to amputation in severe upper extremity trauma. Future research will be necessary to validate these findings and establish standardized protocols for such novel interventions. 

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Published on: Dec 30, 2024 Pages: 42-44

Full Text PDF Full Text HTML DOI: 10.17352/2455-2968.000166
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