Open Access Case Report Article ID: ACG-9-216

    Anal adenosquamous carcinoma on perineal fistula: A case report

    Hajri Amal, Lamnaouar Abderrahmane, Falousse Kabira*, Erreguibi Driss, Boufettal Rachid, Saad Rifki El Jay and Farid Chehab

    Introduction: Adenosquamous Carcinoma (ASC) of the anus presenting both glandular and squamous histopathologic features is a rare colorectal neoplasm.

    Case presentation: A 63-year-old man presented with a one-year history of intermittent rectal pain and bleeding on a perineal fistula. Pathological analysis of the surgical specimen revealed adenosquamous carcinoma of the anus, The patient received neoadjuvant treatment with chemotherapy and radiotherapy over a period of five weeks. then he underwent abdominoperineal resection and a permanent colostomy. Histology revealed invasive adenosquamous carcinoma on the resection specimen and the patient was started on adjuvant therapy with FOLFIRINOX.

    Discussion: Primary ASC of the colon and rectum are extremely rare clinical entities with poor prognosis. Most of the data come from individual case reports and a few small series, making it a challenge to understand the histogenesis of the disease. And the treatment modalities are not yet well codified, which has an impact on overall survival.

    Conclusion: Early diagnosis and radical surgery with other available therapeutic modalities can improve clinical outcomes.


    Published on: Mar 24, 2023 Pages: 4-7

    Full Text PDF Full Text HTML DOI: 10.17352/2455-2283.000116
    CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat


    Pinterest on ACG