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DOI (Digital Object Identifier)- We provide DOI to all published papers to
facilitate higher citation and classification of articles. Peertechz Publisher ID: 10.17352
Research Interest: The overall emphasis of Xiaodong Zheng s
research is to understand the cellular mechanisms by which the
endothelium and smooth muscle regulates blood vessel tone in both normal
physiological conditions and disease states, such as hypoxic pulmonary
hypertension and hypertension. The pulmonary circulation and systemic
circulation display different characterize in response to physiological
stimuli, such as hypoxia. Under hypoxia condition, pulmonary vessels is
constricted, whether the systemic vessels is relaxation. The vascular
tone is regulating through the release of vasoactive mediators of
endothelium in response to either chemical or mechanical stimuli. Some
of these mediators include nitric oxide (NO), prostacyclin, and less
well-understood endothelium-derived hyperpolarizing factors such as
metabolites of arachidonic acid and reactive oxygen species (e.g.
hydrogen peroxide). Of particular interest to our group are the
identities and mechanisms of action of hypoxia in pulmonary and
Indexing/Archiving
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