Primary Amenorrhea: A Müllerian Agenesis Case Report

Blake R. Busey, Rebecca J. Caro* and Dana R. Nguyen

A case of müllerian agenesis, Mayer-Rokitansky-Küster-Hauser (MRKH) Syndrome, in a 16 year-old female with primary amenorrhea is reported. This patient exhibited normal female external physical characteristics with a shallow, blind vaginal pouch upon examination. Serologic hormone evaluation as well as karyotype determination revealed normal pubertal female range hormones and 46, XX, respectively. MRKH Syndrome has a prevalence of 1 in 4000 to 10000 females. Treatment is multi-factorial and should include nonsurgical vaginal dilator therapy, surgical neovaginal options, as well as psychosocial support and counseling on future reproductive options.

Keywords: Primary amenorrhea; Müllerian agenesis; Mayer-Rokitansky-Küester-Hauser Syndrome; MRKH; Blind pouch

Published on: Sep 13, 2014 Pages: 30-32

Full Text PDF Full Text HTML DOI: 10.17352/2455-5282.000010
CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat